(Q40261652)

English

Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species.

scientific article published on June 2006

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scholarly article

1 reference

Europe PubMed Central

19 September 2017

Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho- and caspase-3-cleaved tau species (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673930&resulttype=core&format=json

11 May 2020

Dennis W. Dickson

4

1 reference

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11 May 2020

Kim A. Caldwell

object named as

Kim A Caldwell

12

1 reference

ORCID Public Data File 2021

11

object named as

Guy A Caldwell

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673930&resulttype=core&format=json

11 May 2020

author name string

Chad A Dickey

1

1 reference

Europe PubMed Central

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11 May 2020

Mei Yue

2

1 reference

Europe PubMed Central

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11 May 2020

Wen-Lang Lin

3

1 reference

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11 May 2020

Judith H Dunmore

5

1 reference

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11 May 2020

Wing C Lee

6

1 reference

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11 May 2020

Cynthia Zehr

7

1 reference

Europe PubMed Central

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11 May 2020

Gemma West

8

1 reference

Europe PubMed Central

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11 May 2020

Songsong Cao

9

1 reference

Europe PubMed Central

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11 May 2020

Amber M K Clark

10

1 reference

Europe PubMed Central

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11 May 2020

Christopher Eckman

13

1 reference

Europe PubMed Central

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11 May 2020

Cam Patterson

14

1 reference

Europe PubMed Central

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11 May 2020

Michael Hutton

15

1 reference

Europe PubMed Central

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11 May 2020

Leonard Petrucelli

16

1 reference

Europe PubMed Central

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11 May 2020

language of work or name

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publication date

1 June 2006

1 reference

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19 September 2017

Journal of Neuroscience

1 reference

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11 May 2020

26

1 reference

Europe PubMed Central

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11 May 2020

6985-6996

1 reference

Europe PubMed Central

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11 May 2020

26

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673930&resulttype=core&format=json

11 May 2020

Targets of TGF-beta signaling in Caenorhabditis elegans dauer formation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat shock protein 70 inhibits apoptosis downstream of cytochrome c release and upstream of caspase-3 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformational change as one of the earliest alterations of tau in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Filamentous tau in oligodendrocytes and astrocytes of transgenic mice expressing the human tau isoform with the P301L mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colocalization of Tau and Alpha-Synuclein Epitopes in Lewy Bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of protein phosphatase 2A- and protein phosphatase 1-induced tau hyperphosphorylation and impairment of spatial memory retention in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cdk5 is a key factor in tau aggregation and tangle formation in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple sequence alignment with the Clustal series of programs

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide RNAi screening in Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of ubiquitin-mediated proteolysis in the pathogenesis of neurodegenerative disorders.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CHIP activates HSF1 and confers protection against apoptosis and cellular stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in a novel gene encoding a CRAL-TRIO domain cause human Cayman ataxia and ataxia/dystonia in the jittery mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell Survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid suppresses induction of genes critical for memory consolidation in APP + PS1 transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential profiles of genes expressed in neonatal brain of 129X1/SvJ and C57BL/6J mice: A database to aid in analyzing DNA microarrays using nonisogenic gene-targeted mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in oligodendrocytes is associated with axonal degeneration in P301L tau mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ubiquitin proteasome system in synaptic and axonal degeneration: a new twist to an old cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autosomal dominant parkinsonism associated with variable synuclein and tau pathology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of neurodegenerative disease: role of the ubiquitin proteasome system

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tau suppression in a neurodegenerative mouse model improves memory function

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo evidence of CHIP up-regulation attenuating tau aggregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-Tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The N terminal region of human tau is present in Alzheimer's disease protein A68 and is incorporated into paired helical filaments

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal phosphorylation of tau precedes ubiquitination in neurofibrillary pathology of Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinico-pathologic studies in dementia: nondemented subjects with pathologically confirmed Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genetics of Caenorhabditis elegans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hereditary leucodystrophy in the mouse: the new mutant twitcher

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Twitcher mouse: an enzymatically authentic model of human globoid cell leukodystrophy (Krabbe disease)

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitin is conjugated with amino-terminally processed tau in paired helical filaments

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning and expression of cDNA for murine galactocerebrosidase and mutation analysis of the twitcher mouse, a model of Krabbe's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitin immunoreactivity of paired helical filaments differs in Alzheimer's disease and corticobasal degeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16807328

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0746-06.2006

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673930&resulttype=core&format=json

11 May 2020

release_am2ul7cjafbnjgxjahmvlnrnxe

1 reference

https://api.fatcat.wiki/v0/release/am2ul7cjafbnjgxjahmvlnrnxe

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673930&resulttype=core&format=json

11 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6673930&resulttype=core&format=json

11 May 2020

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