(Q26781260)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

title

Critical Role of Tumor Microenvironment in Shaping NK Cell Functions: Implication of Hypoxic Stress (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Linda Ziani

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

7

Salem Chouaib

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

author name string

Yosra Messai

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Jerome Thiery

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Jean-Henri Bouhris

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

Muhammad Zaeem Noman

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

language of work or name

English

0 references

publication date

23 September 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

published in

Frontiers in Immunology

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

page(s)

482

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json

Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer

26 February 2020

cites work

1 reference

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7 April 2017

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Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells

7 April 2017

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Innate and adaptive immune cells in the tumor microenvironment

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HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

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7 April 2017

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Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene

7 April 2017

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Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

7 April 2017

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Coordinated regulation of myeloid cells by tumours

7 April 2017

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The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma

7 April 2017

1 reference

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Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

7 April 2017

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Cancer statistics, 2006

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The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies

7 April 2017

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

7 April 2017

1 reference

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NK Cells and Cancer Immunoediting

7 April 2017

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Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner

28 September 2017

1 reference

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Dendritic cell regulation of NK-cell responses involves lymphotoxin-α, IL-12, and TGF-β.

28 September 2017

1 reference

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Antitumor immunity. A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection

28 September 2017

1 reference

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CXCL10-induced migration of adoptively transferred human natural killer cells toward solid tumors causes regression of tumor growth in vivo

28 September 2017

1 reference

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Human natural killer cells: origin, receptors, function, and clinical applications

28 September 2017

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ITPR1 protects renal cancer cells against natural killer cells by inducing autophagy

28 September 2017

1 reference

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Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells

28 September 2017

1 reference

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Importance of carcinoma-associated fibroblast-derived proteins in clinical oncology.

28 September 2017

1 reference

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Acute myeloid leukemia impairs natural killer cells through the formation of a deficient cytotoxic immunological synapse.

28 September 2017

1 reference

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Effect of tumor cells and tumor microenvironment on NK-cell function.

28 September 2017

1 reference

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Cancer-associated fibroblasts as another polarized cell type of the tumor microenvironment

28 September 2017

1 reference

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c-Myc regulates expression of NKG2D ligands ULBP1/2/3 in AML and modulates their susceptibility to NK-mediated lysis

28 September 2017

1 reference

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Regulation of the anti-tumour immune response by cancer-associated fibroblasts

28 September 2017

1 reference

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Cutting edge: Hypoxia-induced Nanog favors the intratumoral infiltration of regulatory T cells and macrophages via direct regulation of TGF-β1.

28 September 2017

1 reference

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Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

28 September 2017

1 reference

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'Cancer associated fibroblasts'--more than meets the eye.

28 September 2017

1 reference

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Hypoxia induced impairment of NK cell cytotoxicity against multiple myeloma can be overcome by IL-2 activation of the NK cells.

28 September 2017

1 reference

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Hypoxia stimulates the EMT of gastric cancer cells through autocrine TGFβ signaling

28 September 2017

1 reference

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Targeting the HIF pathway in inflammation and immunity

28 September 2017

1 reference

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Neuroblastoma-derived TGF-β1 modulates the chemokine receptor repertoire of human resting NK cells.

28 September 2017

1 reference

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Surfactant protein A suppresses lung cancer progression by regulating the polarization of tumor-associated macrophages.

28 September 2017

1 reference

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Carcinoma-associated fibroblasts: non-neoplastic tumour-promoting mesenchymal cells.

28 September 2017

1 reference

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Regulation of ligands for the NKG2D activating receptor

28 September 2017

1 reference

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Tumor-associated macrophages: function, phenotype, and link to prognosis in human lung cancer.

28 September 2017

1 reference

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Hypoxia downregulates the expression of cell surface MICA without increasing soluble MICA in osteosarcoma cells in a HIF-1α-dependent manner

28 September 2017

1 reference

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Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche.

28 September 2017

1 reference

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Cell-mediated autophagy promotes cancer cell survival.

28 September 2017

1 reference

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Melanoma cells inhibit natural killer cell function by modulating the expression of activating receptors and cytolytic activity

28 September 2017

1 reference

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Microenvironmental hypoxia orchestrating the cell stroma cross talk, tumor progression and antitumor response

28 September 2017

1 reference

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Use of allogeneic NK cells for cancer immunotherapy.

28 September 2017

1 reference

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Complex regulation of human NKG2D-DAP10 cell surface expression: opposing roles of the γc cytokines and TGF-β1.

28 September 2017

1 reference

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Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.

28 September 2017

1 reference

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Adoptive immunotherapy with cytokine-induced killer cells for patients with relapsed hematologic malignancies after allogeneic hematopoietic cell transplantation

28 September 2017

1 reference

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The role of HIF-1 in up-regulating MICA expression on human renal proximal tubular epithelial cells during hypoxia/reoxygenation

28 September 2017

1 reference

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Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha

28 September 2017

1 reference

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Blood dendritic cells suppress NK cell function and increase the risk of leukemia relapse after hematopoietic cell transplantation

28 September 2017

1 reference

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A phase II study of allogeneic natural killer cell therapy to treat patients with recurrent ovarian and breast cancer

28 September 2017

1 reference

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The polarization of immune cells in the tumour environment by TGFbeta

28 September 2017

1 reference

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Cytotoxicity of activated natural killer cells against pediatric solid tumors

28 September 2017

1 reference

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The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody

28 September 2017

1 reference

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Activation of fibroblasts in cancer stroma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Tumor immunoediting by NKp46.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

NK depletion results in increased CCL22 secretion and Treg levels in Lewis lung carcinoma via the accumulation of CCL22-secreting CD11b+CD11c+ cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity

28 September 2017

1 reference

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Cancer associated fibroblasts in cancer pathogenesis

28 September 2017

1 reference

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Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor.

28 September 2017

1 reference

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Cancer stem cells, hypoxia and metastasis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Human dendritic cells produce TGF-beta 1 under the influence of lung carcinoma cells and prime the differentiation of CD4+CD25+Foxp3+ regulatory T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Accelerated tumor growth in mice deficient in DNAM-1 receptor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Natural killer cell-directed therapies: moving from unexpected results to successful strategies

28 September 2017

1 reference

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Hypoxia and metabolism. Hypoxia, DNA repair and genetic instability.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Human leukocyte antigen-B-associated transcript 3 is released from tumor cells and engages the NKp30 receptor on natural killer cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Dominant-negative HIF-3 alpha 4 suppresses VHL-null renal cell carcinoma progression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

The evolving concept of tumor microenvironments

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Antitumor activity of NK cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Role of hypoxia-inducible factor-1alpha as a cancer therapy target

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Soluble ULBP suppresses natural killer cell activity via down-regulating NKG2D expression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Regulatory T cells, tumour immunity and immunotherapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

CD4+CD25+ T regulatory cells suppress NK cell-mediated immunotherapy of cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Exploitation of alloreactive NK cells in adoptive immunotherapy of cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

CD4+CD25+ T regulatory cells inhibit cytotoxic activity of T CD8+ and NK lymphocytes in the direct cell-to-cell interaction

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Hypoxia-mediated down-regulation of Bid and Bax in tumors occurs via hypoxia-inducible factor 1-dependent and -independent mechanisms and contributes to drug resistance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Hypoxia, clonal selection, and the role of HIF-1 in tumor progression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Enhanced tumor growth and invasiveness in vivo by a carboxyl-terminal fragment of alpha1-proteinase inhibitor generated by matrix metalloproteinases: a possible modulatory role in natural killer cytotoxicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Myeloid expression of adenosine A2A receptor suppresses T and NK cell responses in the solid tumor microenvironment

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

NK cell receptor NKp46 regulates graft-versus-host disease

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Hypoxia downregulates the expression of activating receptors involved in NK-cell-mediated target cell killing without affecting ADCC.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Natural killer cell-mediated basal and interferon-enhanced cytotoxicity against liver cancer cells is significantly impaired under in vivo oxygen conditions.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Oxygen(es) and the hypoxia-inducible factor-1.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Role of organ-associated NK cells in decreased formation of experimental metastases in lung and liver.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585210

Immune infiltrates are prognostic factors in localized gastrointestinal stromal tumors

31 May 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00482

Cord blood CD4(+)CD25(+) regulatory T cells fail to inhibit cord blood NK cell functions due to insufficient production and expression of TGF-beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00482

Colorectal carcinoma-derived fibroblasts modulate natural killer cell phenotype and antitumor cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00482

Full haplotype-mismatched hematopoietic stem-cell transplantation: a phase II study in patients with acute leukemia at high risk of relapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00482

Gene transfer of antisense hypoxia inducible factor-1 alpha enhances the therapeutic efficacy of cancer immunotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00482

Successful transfer of alloreactive haploidentical KIR ligand-mismatched natural killer cells after infusion in elderly high risk acute myeloid leukemia patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00482

Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFIMMU.2015.00482

Morphological studies of effector cell-microvessel interactions in adoptive immunotherapy in tumor-bearing animals

21 January 2018

1 reference

12 December 2020

Depletion of NK cell activity results in growth of hepatic micrometastases in a murine ocular melanoma model

1 reference

12 December 2020

Hepatocellular carcinoma-associated fibroblasts trigger NK cell dysfunction via PGE2 and IDO

1 reference

12 December 2020

Hypoxia and reoxygenation do not upregulate adhesion molecules and natural killer cell adhesion on human endothelial cells in vitro

1 reference

12 December 2020

CD4-8- dendritic cells prime CD4+ T regulatory 1 cells to suppress antitumor immunity

1 reference

12 December 2020

Regulatory T cells control dendritic cell/NK cell cross-talk in lymph nodes at the steady state by inhibiting CD4+ self-reactive T cells

1 reference

12 December 2020

Identifiers

DOI

10.3389/FIMMU.2015.00482

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json

release_jjv3roiqgncizhu6ope2q4k6x4

26 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/jjv3roiqgncizhu6ope2q4k6x4

24 November 2022

mapped directly with Wikidata item

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26441986%20AND%20SRC:MED&resulttype=core&format=json