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GAB2--a scaffolding protein in cancer
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2 references
stated in
PubMed
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Europe PubMed Central
PMC publication ID
3810274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22871571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
title
GAB2--a scaffolding protein in cancer
(English)
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3810274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22871571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
author
Iraz T Aydin
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3810274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22871571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
author name string
Sarah J Adams
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3810274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22871571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
Julide T Celebi
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3810274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22871571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
language of work or name
English
1 reference
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publication date
7 August 2012
1 reference
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Europe PubMed Central
PMC publication ID
3810274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22871571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
published in
Molecular Cancer Research
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3810274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22871571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
volume
10
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3810274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22871571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
issue
10
2 references
stated in
PubMed
stated in
Europe PubMed Central
PMC publication ID
3810274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22871571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
page(s)
1265-1270
1 reference
stated in
Europe PubMed Central
PMC publication ID
3810274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22871571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
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Essential role for Gab2 in the allergic response
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7 April 2017
Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation
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GAB2 induces tumor angiogenesis in NRAS-driven melanoma.
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RAS/RAF/MEK/ERK and PI3K/PTEN/AKT Signaling in Malignant Melanoma Progression and Therapy
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28 September 2017
Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cells
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PubMed Central
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28 September 2017
Gab2 promotes colony-stimulating factor 1-regulated macrophage expansion via alternate effectors at different stages of development.
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PubMed Central
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Pivotal role of reduced let-7g expression in breast cancer invasion and metastasis
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28 September 2017
Gab2 regulates cytoskeletal organization and migration of mammary epithelial cells by modulating RhoA activation
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PubMed Central
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A germline gain-of-function mutation in Ptpn11 (Shp-2) phosphatase induces myeloproliferative disease by aberrant activation of hematopoietic stem cells
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Gab2 promotes hematopoietic stem cell maintenance and self-renewal synergistically with STAT5
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28 September 2017
The GAB2 signaling scaffold promotes anchorage independence and drives a transcriptional response associated with metastatic progression of breast cancer
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Gab2-mediated signaling promotes melanoma metastasis
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Lyn regulates BCR-ABL and Gab2 tyrosine phosphorylation and c-Cbl protein stability in imatinib-resistant chronic myelogenous leukemia cells
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28 September 2017
Gab2 and Src co-operate in human mammary epithelial cells to promote growth factor independence and disruption of acinar morphogenesis.
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PubMed Central
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28 September 2017
Involvement of the Gab2 scaffolding adapter in type I interferon signalling
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PubMed Central
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28 September 2017
Abnormal hematopoiesis in Gab2 mutant mice
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PubMed Central
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28 September 2017
PLCgamma2 regulates osteoclastogenesis via its interaction with ITAM proteins and GAB2.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3810274
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28 September 2017
Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance
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28 September 2017
The multiple function of Grb2 associated binder (Gab) adaptor/scaffolding protein in immune cell signaling.
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28 September 2017
A role for the scaffolding adapter GAB2 in breast cancer
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PubMed Central
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28 September 2017
GRB2-mediated recruitment of GAB2, but not GAB1, to SF-STK supports the expansion of Friend virus-infected erythroid progenitor cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3810274
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28 September 2017
Inherited predispositions and hyperactive Ras in myeloid leukemogenesis
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28 September 2017
Impaired Shc, Ras, and MAPK activation but normal Akt activation in FL5.12 cells expressing an insulin-like growth factor I receptor mutated at tyrosines 1250 and 1251.
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28 September 2017
The "Gab" in signal transduction.
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28 September 2017
The docking protein Gab2 is overexpressed and estrogen regulated in human breast cancer
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PubMed Central
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28 September 2017
The gift of Gab.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3810274
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28 September 2017
TEL-JAK2 mediates constitutive activation of the phosphatidylinositol 3'-kinase/protein kinase B signaling pathway
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PubMed Central
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28 September 2017
Scaffolding protein Gab2 mediates differentiation signaling downstream of Fms receptor tyrosine kinase
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3810274
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28 September 2017
Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases
1 reference
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PubMed Central
reference URL
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28 September 2017
The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3810274
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28 September 2017
Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3810274
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28 September 2017
Amplification of oncogenes in human cancer cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3810274
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31 May 2018
The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene
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PubMed Central
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31 May 2018
Overexpression of the oncogenic signal transducer Gab2 occurs early in breast cancer development
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3810274
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28 November 2018
The Tyrosine Phosphatase Shp2 Interacts with NPM-ALK and Regulates Anaplastic Lymphoma Cell Growth and Migration
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PubMed Central
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28 November 2018
Role of Gab2 in mammary tumorigenesis and metastasis.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3810274
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28 November 2018
Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI3-kinase in myeloid leukemias
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PubMed Central
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28 November 2018
Enhanced sensitivity to inhibition of SHP2, STAT5, and Gab2 expression in chronic myeloid leukemia (CML).
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PubMed Central
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28 November 2018
The pleckstrin homology domain of Gab-2 is required for optimal interleukin-3 signalsome-mediated responses
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3810274
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28 November 2018
Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations.
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PubMed Central
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28 November 2018
Cyclin D1 is a candidate oncogene in cutaneous melanoma
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PubMed Central
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28 November 2018
Amplification of genes within the chromosome 11q13 region is indicative of poor prognosis in patients with operable breast cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3810274
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28 November 2018
Epidermal Growth Factor-induced DNA Synthesis
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/22871571
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A conserved inositol phospholipid binding site within the pleckstrin homology domain of the Gab1 docking protein is required for epithelial morphogenesis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22871571
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
GAB2 is a novel target of 11q amplification in AML/MDS
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22871571
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Amplification of 11q13 in ovarian carcinoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22871571
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/1541-7786.MCR-12-0352
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3453994
stated in
Europe PubMed Central
PMC publication ID
3810274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22871571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
OpenCitations bibliographic resource ID
3453994
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3453994
PMC publication ID
3810274
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3453994
stated in
Europe PubMed Central
PMC publication ID
3810274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22871571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
PubMed publication ID
22871571
2 references
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3453994
stated in
Europe PubMed Central
PMC publication ID
3810274
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22871571%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 February 2020
ResearchGate publication ID
230632137
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