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Chemical probes of endocannabinoid metabolism
scientific article published in April 2013
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title
Chemical probes of endocannabinoid metabolism
(English)
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PubMed
main subject
endocannabinoids
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author name string
J. L. Blankman
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1
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B. F. Cravatt
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2
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language of work or name
English
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PubMed
publication date
April 2013
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published in
Pharmacological Reviews
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volume
65
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PubMed
issue
2
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PubMed
page(s)
849-71
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cites work
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Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects
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N-arachidonyl maleimide potentiates the pharmacological and biochemical effects of the endocannabinoid 2-arachidonylglycerol through inhibition of monoacylglycerol lipase
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Cannabinoids in health and disease
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Inactivation of N-acyl phosphatidylethanolamine phospholipase D reveals multiple mechanisms for the biosynthesis of endocannabinoids
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Brain monoglyceride lipase participating in endocannabinoid inactivation
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Reversible Competitive α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Containing Additional Conformational Constraints in the Acyl Side Chain: Orally Active, Long-Acting Analgesics
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Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain
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Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling
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21 March 2017
Molecular characterization of a phospholipase D generating anandamide and its congeners
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Purification and some properties of a monoacylglycerol-hydrolyzing enzyme of rat adipose tissue
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FAAH and MAGL inhibitors: therapeutic opportunities from regulating endocannabinoid levels
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A FAAH-regulated class of N-acyl taurines that activates TRP ion channels
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Identification of a high-affinity binding site involved in the transport of endocannabinoids
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Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus
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Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice
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cDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase. Evolutionary relationship to esterases, lysophospholipases, and haloperoxidases
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Methyl arachidonyl fluorophosphonate: a potent irreversible inhibitor of anandamide amidase
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Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist
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Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
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2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain
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Correlation between the in vivo and an in vitro expression of opiate withdrawal precipitated by naloxone: their antagonism by l-(-)-delta9-tetrahydrocannabinol
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Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system
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The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission
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Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice
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21 March 2017
The inhibition of monoacylglycerol lipase by URB602 showed an anti-inflammatory and anti-nociceptive effect in a murine model of acute inflammation
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Biosynthesis of anandamide and N-palmitoylethanolamine by sequential actions of phospholipase A2 and lysophospholipase D
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Isolation and structure of a brain constituent that binds to the cannabinoid receptor
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Modulation of anxiety through blockade of anandamide hydrolysis
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Formation and inactivation of endogenous cannabinoid anandamide in central neurons
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Selective inhibition of alpha/beta-hydrolase domain 6 attenuates neurodegeneration, alleviates blood brain barrier breakdown, and improves functional recovery in a mouse model of traumatic brain injury
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Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics follo
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A dysregulated endocannabinoid-eicosanoid network supports pathogenesis in a mouse model of Alzheimer's disease
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Pharmacological characterization of the peripheral FAAH inhibitor URB937 in female rodents: interaction with the Abcg2 transporter in the blood-placenta barrier
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The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model
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An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis
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28 September 2017
α-Ketoheterocycle-based Inhibitors of Fatty Acid Amide Hydrolase (FAAH).
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28 September 2017
Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates
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28 September 2017
The novel reversible fatty acid amide hydrolase inhibitor ST4070 increases endocannabinoid brain levels and counteracts neuropathic pain in different animal models.
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28 September 2017
Peripheral FAAH inhibition causes profound antinociception and protects against indomethacin-induced gastric lesions
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28 September 2017
Inhibitors of the endocannabinoid-degrading enzymes, or how to increase endocannabinoid's activity by preventing their hydrolysis
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28 September 2017
A catalytically silent FAAH-1 variant drives anandamide transport in neurons
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28 September 2017
Assessment of the pharmacology and tolerability of PF-04457845, an irreversible inhibitor of fatty acid amide hydrolase-1, in healthy subjects
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28 September 2017
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation
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28 September 2017
Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Increasing 2-arachidonoyl glycerol signaling in the periphery attenuates mechanical hyperalgesia in a model of bone cancer pain
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28 September 2017
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28 September 2017
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28 September 2017
Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay
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28 September 2017
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28 September 2017
Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
DAG Lipase Involvement in Depolarization-Induced Suppression of Inhibition: Does Endocannabinoid Biosynthesis Always Meet the Demand?
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Characterization of mice lacking candidate N-acyl ethanolamine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo
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28 September 2017
FAAH-/- mice display differential tolerance, dependence, and cannabinoid receptor adaptation after delta 9-tetrahydrocannabinol and anandamide administration
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28 September 2017
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28 September 2017
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28 September 2017
Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo.
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28 September 2017
Non-CB1, non-CB2 receptors for endocannabinoids, plant cannabinoids, and synthetic cannabimimetics: focus on G-protein-coupled receptors and transient receptor potential channels
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28 September 2017
Cannabinoids as pharmacotherapies for neuropathic pain: from the bench to the bedside
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28 September 2017
Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances retrograde endocannabinoid signaling
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28 September 2017
A second generation of carbamate-based fatty acid amide hydrolase inhibitors with improved activity in vivo
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28 September 2017
Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism
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28 September 2017
The endocannabinoid system as a target for novel anxiolytic and antidepressant drugs
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28 September 2017
Blockade of endocannabinoid-degrading enzymes attenuates neuropathic pain
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28 September 2017
Endocannabinoid chemical biology: a tool for the development of novel therapies
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28 September 2017
Inhibitors of endocannabinoid-metabolizing enzymes reduce precipitated withdrawal responses in THC-dependent mice
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28 September 2017
The FAAH inhibitor URB-597 interferes with cisplatin- and nicotine-induced vomiting in the Suncus murinus (house musk shrew)
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28 September 2017
Emerging strategies for exploiting cannabinoid receptor agonists as medicines
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28 September 2017
Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation
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28 September 2017
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28 September 2017
A decrease in anandamide signaling contributes to the maintenance of cutaneous mechanical hyperalgesia in a model of bone cancer pain
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28 September 2017
Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates
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28 September 2017
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28 September 2017
Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels
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28 September 2017
The pharmacology and therapeutic relevance of endocannabinoid derived cyclo-oxygenase (COX)-2 products
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28 September 2017
Modulation of the anti-nociceptive effects of 2-arachidonoyl glycerol by peripherally administered FAAH and MGL inhibitors in a neuropathic pain model
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28 September 2017
Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
Anandamide biosynthesis catalyzed by the phosphodiesterase GDE1 and detection of glycerophospho-N-acyl ethanolamine precursors in mouse brain
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28 September 2017
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28 September 2017
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28 September 2017
Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: a critical revisitation
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28 September 2017
Identification of a novel endocannabinoid-hydrolyzing enzyme expressed by microglial cells
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28 September 2017
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28 September 2017
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28 September 2017
The putative endocannabinoid transport blocker LY2183240 is a potent inhibitor of FAAH and several other brain serine hydrolases
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
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28 September 2017
A missense mutation in human fatty acid amide hydrolase associated with problem drug use.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 September 2017
Oxidative metabolism of endocannabinoids
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 September 2017
Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 September 2017
Molecular mechanisms of neurotransmitter release
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 September 2017
Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 September 2017
Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 September 2017
Properties of rat liver N-acylethanolamine amidohydrolase
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 September 2017
The role of receptor subtype diversity in the CNS.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 September 2017
Δ9-Tetrahydrocannabinol discrimination in rats as a model for cannabis intoxication
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 September 2017
O-hydroxyacetamide carbamates as a highly potent and selective class of endocannabinoid hydrolase inhibitors
1 reference
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PubMed Central
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31 May 2018
Inhibitors of monoacylglycerol lipase, fatty-acid amide hydrolase and endocannabinoid transport differentially suppress capsaicin-induced behavioral sensitization through peripheral endocannabinoid mechanisms
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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31 May 2018
Benzothiophene piperazine and piperidine urea inhibitors of fatty acid amide hydrolase (FAAH)
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PubMed Central
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31 May 2018
Development of a potent inhibitor of 2-arachidonoylglycerol hydrolysis with antinociceptive activity in vivo
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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31 May 2018
Inhibition of fatty acid amide hydrolase produces PPAR-alpha-mediated analgesia in a rat model of inflammatory pain
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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31 May 2018
Specific alterations of extracellular endocannabinoid levels in the nucleus accumbens by ethanol, heroin, and cocaine self-administration.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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31 May 2018
The antinociceptive effects of intraplantar injections of 2-arachidonoyl glycerol are mediated by cannabinoid CB2 receptors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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31 May 2018
Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta-hydrolase 4 in this pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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31 May 2018
Abstinence symptoms following smoked marijuana in humans
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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31 May 2018
Trifluoromethyl ketone inhibitors of fatty acid amide hydrolase: a probe of structural and conformational features contributing to inhibition
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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31 May 2018
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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31 May 2018
Differential role of anandamide and 2-arachidonoylglycerol in memory and anxiety-like responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
A new group of oxime carbamates as reversible inhibitors of fatty acid amide hydrolase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
Enol carbamates as inhibitors of fatty acid amide hydrolase (FAAH) endowed with high selectivity for FAAH over the other targets of the endocannabinoid system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
Thiadiazolopiperazinyl ureas as inhibitors of fatty acid amide hydrolase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
CB1 receptor-mediated control of the release of endocannabinoids (as assessed by microdialysis coupled with LC/MS) in the rat hypothalamus
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
The effect of cannabidiol and URB597 on conditioned gaping (a model of nausea) elicited by a lithium-paired context in the rat.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
retrieved
28 November 2018
Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
retrieved
28 November 2018
Cocaine- and amphetamine-related transcript is involved in the orexigenic effect of endogenous anandamide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
retrieved
28 November 2018
Synaptically driven endocannabinoid release requires Ca2+-assisted metabotropic glutamate receptor subtype 1 to phospholipase Cbeta4 signaling cascade in the cerebellum.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
retrieved
28 November 2018
Characterization of the sulfhydryl-sensitive site in the enzyme responsible for hydrolysis of 2-arachidonoyl-glycerol in rat cerebellar membranes
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
Overweight and obesity associated with a missense polymorphism in fatty acid amide hydrolase (FAAH).
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stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
Phospholipase Cbeta serves as a coincidence detector through its Ca2+ dependency for triggering retrograde endocannabinoid signal
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
RNA interference suggests a primary role for monoacylglycerol lipase in the degradation of the endocannabinoid 2-arachidonoylglycerol
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
Reduced cellular expression and activity of the P129T mutant of human fatty acid amide hydrolase: evidence for a link between defects in the endocannabinoid system and problem drug use.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
retrieved
28 November 2018
Segregation of two endocannabinoid-hydrolyzing enzymes into pre- and postsynaptic compartments in the rat hippocampus, cerebellum and amygdala.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
Reversible inhibitors of fatty acid amide hydrolase that promote analgesia: evidence for an unprecedented combination of potency and selectivity
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
Identification of a potent and highly efficacious, yet slowly desensitizing CB1 cannabinoid receptor agonist
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
Activity-based protein profiling in vivo using a copper(i)-catalyzed azide-alkyne [3 + 2] cycloaddition
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
Pharmacological activity of fatty acid amides is regulated, but not mediated, by fatty acid amide hydrolase in vivo
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
Biosynthesis of an endogenous cannabinoid precursor in neurons and its control by calcium and cAMP.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
retrieved
28 November 2018
Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
retrieved
28 November 2018
Subcellular Localization and Some Properties of Monoacyiglycerol Lipase in Rat Adipocytes
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
retrieved
28 November 2018
Biosynthesis of N-acylethanolamine phospholipids by dog brain preparations
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3639726
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28 November 2018
Facilitation of CB1 receptor-mediated neurotransmission decreases marble burying behavior in mice
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/23512546
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 2. Discovery of 7-azaspiro[3.5]nonane urea PF-04862853, an orally efficacious inhibitor of fatty acid amide hydrolase (FAAH) for pain
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23512546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Anandamide amidohydrolase activity in rat brain microsomes. Identification and partial characterization
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23512546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Partial purification and characterization of the porcine brain enzyme hydrolyzing and synthesizing anandamide
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23512546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Two novel classes of neuroactive fatty acid amides are substrates for mouse neuroblastoma ‘anandamide amidohydrolase’
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23512546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Fatty acid sulfonyl fluorides inhibit anandamide metabolism and bind to the cannabinoid receptor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23512546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Novel inhibitors of fatty acid amide hydrolase
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23512546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A new perspective on cannabinoid signalling: complementary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23512546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Characterization of the kinetics and distribution of N-arachidonylethanolamine (anandamide) hydrolysis by rat brain
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23512546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Inhibitors of arachidonoyl ethanolamide hydrolysis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23512546
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1124/PR.112.006387
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1447630
OpenCitations bibliographic resource ID
1447630
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1447630
PMC publication ID
3639726
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1447630
PubMed publication ID
23512546
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1447630
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