(Q26863534)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22778499%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

3 October 2022

Role of prostaglandins in neuroinflammatory and neurodegenerative diseases (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22778499%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

25 April 2019

1 reference

19 November 2019

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22778499%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

4

Bernd L Fiebich

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22778499%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

author name string

Isabel Vieira de Assis Lima

series ordinal

1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22778499%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Marcelo Limborço-Filho

series ordinal

3

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22778499%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Antonio Carlos Pinheiro de Oliveira

series ordinal

5

2 references

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7 February 2020

language of work or name

1 reference

18 June 2012

4 references

25 April 2019

19 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22778499%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

3 October 2022

Mediators of Inflammation

5 references

25 April 2019

19 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22778499%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

3 October 2022

2012

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22778499%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

page(s)

946813

2 references

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Creative Commons Attribution 3.0 Unported

7 February 2020

copyright license

3 references

25 April 2019

19 November 2019

on focus list of Wikimedia project

3 October 2022

copyright status

copyrighted

0 references

ScienceSource

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cites work

Elevated microsomal prostaglandin-E synthase-1 in Alzheimer's disease

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Selective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's disease

21 March 2017

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Expression and localization of cyclooxygenase‐1 and ‐2 in human sporadic amyotrophic lateral sclerosis

21 March 2017

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Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis

21 March 2017

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Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

21 March 2017

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Does neuroinflammation fan the flame in neurodegenerative diseases?

21 March 2017

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Resveratrol potently reduces prostaglandin E2 production and free radical formation in lipopolysaccharide-activated primary rat microglia

21 March 2017

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Non-steroidal anti-inflammatory drugs in Parkinson's disease

21 March 2017

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Nonsteroidal antiinflammatory drug use and the risk for Parkinson's disease

21 March 2017

1 reference

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Anti-inflammatory treatment with acetylsalicylate or rofecoxib is not neuroprotective in Huntington's disease transgenic mice

21 March 2017

1 reference

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Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease

21 March 2017

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21 March 2017

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Inhibition of the cyclooxygenase isoenzymes COX-1 and COX-2 provide neuroprotection in the MPTP-mouse model of Parkinson's disease

21 March 2017

1 reference

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Oxidative stress in neurodegeneration: cause or consequence?

21 March 2017

1 reference

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Suppressing inflammatory cascade by cyclo-oxygenase inhibitors attenuates quinolinic acid induced Huntington's disease-like alterations in rats

21 March 2017

1 reference

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Regulation of prostaglandin E2 synthase expression in activated primary rat microglia: evidence for uncoupled regulation of mPGES-1 and COX-2

21 March 2017

1 reference

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Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

21 March 2017

1 reference

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Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism

7 April 2017

1 reference

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Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

7 April 2017

1 reference

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Peripheral inflammation increases the damage in animal models of nigrostriatal dopaminergic neurodegeneration: possible implication in Parkinson's disease incidence.

7 April 2017

1 reference

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Role of LOX/COX pathways in 3-nitropropionic acid-induced Huntington's disease-like symptoms in rats: protective effect of licofelone

28 September 2017

1 reference

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Use of non-steroidal anti-inflammatory drugs and risk of Parkinson's disease: nested case-control study

28 September 2017

1 reference

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Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy.

28 September 2017

1 reference

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Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis

28 September 2017

1 reference

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Neuroinflammation in Huntington's disease

28 September 2017

1 reference

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The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity

28 September 2017

1 reference

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The role of neuroinflammation on the pathogenesis of Parkinson's disease

28 September 2017

1 reference

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Microglia in the aging brain: relevance to neurodegeneration

28 September 2017

1 reference

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Cyclopentenone prostaglandin-induced unfolding and aggregation of the Parkinson disease-associated UCH-L1.

28 September 2017

1 reference

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Targeting glial cells to elucidate the pathogenesis of Huntington's disease.

28 September 2017

1 reference

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Protective effect of rofecoxib and nimesulide against intra-striatal quinolinic acid-induced behavioral, oxidative stress and mitochondrial dysfunctions in rats

28 September 2017

1 reference

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Targeted lipidomics reveals mPGES-1-PGE2 as a therapeutic target for multiple sclerosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

NSAID use and the risk of Parkinson's disease: systematic review and meta-analysis of observational studies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Microsomal prostaglandin E synthase-2: cellular distribution and expression in Alzheimer's disease

28 September 2017

1 reference

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Impaired cognition, sensorimotor gating, and hippocampal long-term depression in mice lacking the prostaglandin E2 EP2 receptor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Prostaglandin E2 stimulates the production of amyloid-beta peptides through internalization of the EP4 receptor.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Differing roles for members of the phospholipase A2 superfamily in experimental autoimmune encephalomyelitis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

The prostaglandin E2 EP2 receptor accelerates disease progression and inflammation in a model of amyotrophic lateral sclerosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Microglial dysfunction and defective beta-amyloid clearance pathways in aging Alzheimer's disease mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Prostaglandin receptor EP2 protects dopaminergic neurons against 6-OHDA-mediated low oxidative stress

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Involvement of prostaglandin E2 in production of amyloid-beta peptides both in vitro and in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Effects of the adenosine A2A receptor antagonist SCH 58621 on cyclooxygenase-2 expression, glial activation, and brain-derived neurotrophic factor availability in a rat model of striatal neurodegeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Peroxisome proliferator-activated receptor-gamma agonists suppress the production of IL-12 family cytokines by activated glia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) and ciglitazone modulate Staphylococcus aureus-dependent astrocyte activation primarily through a PPAR-gamma-independent pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Always around, never the same: pathways of amyloid beta induced neurodegeneration throughout the pathogenic cascade of Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Microglial senescence: does the brain's immune system have an expiration date?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Cytoskeleton/endoplasmic reticulum collapse induced by prostaglandin J2 parallels centrosomal deposition of ubiquitinated protein aggregates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Innate immunity in amyotrophic lateral sclerosis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

The role of inflammation in CNS injury and disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Novel therapeutic opportunities for Alzheimer's disease: focus on nonsteroidal anti-inflammatory drugs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Neuroinflammation: a potential therapeutic target

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Cytosolic phospholipase A2 alpha-deficient mice are resistant to experimental autoimmune encephalomyelitis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Coxibs and cardiovascular disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Cyclooxygenase-2 (COX-2) in inflammatory and degenerative brain diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

COX-2 and neurodegeneration in Parkinson's disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Multiple elements of the allergic arm of the immune response modulate autoimmune demyelination.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Prostaglandin A1 inhibits rotenone-induced apoptosis in SH-SY5Y cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

15-Deoxy-Delta(12,14)-prostaglandin J(2): the endogenous electrophile that induces neuronal apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Identification and characterization of a novel type of membrane-associated prostaglandin E synthase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Marked increase in cyclooxygenase-2 in ALS spinal cord: implications for therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

15-deoxy-delta12,14-prostaglandin J2, a specific ligand for peroxisome proliferator-activated receptor-gamma, induces neuronal apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Selective dopamine receptor stimulation differentially affects [3H]arachidonic acid incorporation, a surrogate marker for phospholipase A2-mediated neurotransmitter signal transduction, in a rodent model of Parkinson's disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Glial cells and Parkinson's disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Prostaglandin E receptor subtypes in cultured rat microglia and their role in reducing lipopolysaccharide-induced interleukin-1beta production

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Principles of neuronal regeneration.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Nitric oxide-mediated neuronal injury in multiple sclerosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Pharmacological inhibition of Akt and downstream pathways modulates the expression of COX-2 and mPGES-1 in activated microglia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Lipid-mediated oxidative stress and inflammation in the pathogenesis of Parkinson's disease

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Anti-inflammatory role of microsomal prostaglandin E synthase-1 in a model of neuroinflammation.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Effects of caffeic acid, rofecoxib, and their combination against quinolinic acid-induced behavioral alterations and disruption in glutathione redox status

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

15d-PGJ2 induces apoptosis of mouse oligodendrocyte precursor cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Prostaglandin E2 receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated alpha-synuclein

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Perineuronal oligodendrocytes protect against neuronal apoptosis through the production of lipocalin-type prostaglandin D synthase in a genetic demyelinating model.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Chronic neuroinflammation in rats reproduces components of the neurobiology of Alzheimer's disease

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Prostaglandins stimulate calcium-dependent glutamate release in astrocytes.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Prostaglandin H synthetase-mediated metabolism of dopamine: implication for Parkinson's disease.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Reactive microglia in patients with senile dementia of the Alzheimer type are positive for the histocompatibility glycoprotein HLA-DR.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Immune system response in Alzheimer's disease.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

The formation of prostaglandins in the postmortem cerebral cortex of Alzheimer-type dementia patients

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Activation of the classical complement pathway in brain tissue of Alzheimer patients

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Microglial cells around amyloid plaques in Alzheimer's disease express leucocyte adhesion molecules of the LFA-1 family

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Anti-inflammatory drugs and Alzheimer disease.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Incidence and severity of experimental allergic encephalomyelitis and cerebral prostaglandin synthesis in essential fatty acid deficient and aspirin-treated rats

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Rat brain arachidonic acid metabolism is increased by a 6-day intracerebral ventricular infusion of bacterial lipopolysaccharide

31 May 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Lipocalin-type prostaglandin D synthase is up-regulated in oligodendrocytes in lysosomal storage diseases and binds gangliosides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Hematopoietic prostaglandin D synthase and DP1 receptor are selectively upregulated in microglia and astrocytes within senile plaques from human patients and in a mouse model of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Effect of enhanced prostacyclin synthesis by adenovirus-mediated transfer on lipopolysaccharide stimulation in neuron-glia cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

CNS-specific prostacyclin ligands as neuronal survival-promoting factors in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Specific ligand for a central type prostacyclin receptor attenuates neuronal damage in a rat model of focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Neuronal cyclooxygenase-2 activity and prostaglandins PGE2, PGD2, and PGF2 alpha exacerbate hypoxic neuronal injury in neuron-enriched primary culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

PGF(2alpha) FP receptor contributes to brain damage following transient focal brain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Cytosolic phospholipase A2 plays a key role in the pathogenesis of multiple sclerosis-like disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Blockade of cytosolic phospholipase A2 alpha prevents experimental autoimmune encephalomyelitis and diminishes development of Th1 and Th17 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

A longitudinal study of the prostaglandin content of central nervous system tissues from guinea pigs with acute experimental allergic encephalomyelitis (EAE).

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

The EAE-associated behavioral syndrome: I. Temporal correlation with inflammatory mediators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Minocycline reduces prostaglandin E synthase expression and 8-isoprostane formation in LPS-activated primary rat microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Anti-inflammatory and analgesic activity of a novel inhibitor of microsomal prostaglandin E synthase-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Peroxisome proliferator-activated receptor-gamma agonists inhibit the activation of microglia and astrocytes: implications for multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Clinical trial of indomethacin in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Cytosolic phospholipase A2 (cPLA2) immunoreactivity is elevated in Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Endogenous PGE2 regulates membrane excitability and synaptic transmission in hippocampal CA1 pyramidal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Distribution of cyclooxygenase-1 and cyclooxygenase-2 mRNAs and proteins in human brain and peripheral organs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Possible Involvement of Small Oligomers of Amyloid-β Peptides in 15-Deoxy-Δ12,14 Prostaglandin J2-Sensitive Microglial Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Cyclooxygenases mRNA and protein expression in striata in the experimental mouse model of Parkinson's disease induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration to mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

MPP+-induced COX-2 activation and subsequent dopaminergic neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Inflammatory regulators in Parkinson's disease: iNOS, lipocortin-1, and cyclooxygenases-1 and -2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

COX-2-deficient mice are less prone to MPTP-neurotoxicity than wild-type mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Cyclooxygenase-2-deficient mice are resistant to 1-methyl-4-phenyl1, 2, 3, 6-tetrahydropyridine-induced damage of dopaminergic neurons in the substantia nigra.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Striatal 6-OHDA lesion in mice: Investigating early neurochemical changes underlying Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Identification of actin as a 15-deoxy-Delta12,14-prostaglandin J2 target in neuroblastoma cells: mass spectrometric, computational, and functional approaches to investigate the effect on cytoskeletal derangement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Delta12-Prostaglandin J2 inhibits the ubiquitin hydrolase UCH-L1 and elicits ubiquitin-protein aggregation without proteasome inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Integrative role of cPLA with COX-2 and the effect of non-steriodal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Cytosolic phospholipase A2 is induced in reactive glia following different forms of neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Increased expression and activation of cytosolic phospholipase A2 in the spinal cord of patients with sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Increased levels of the pro-inflammatory prostaglandin PGE2 in CSF from ALS patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Effects of intraperitoneal injection of Rofecoxib in a mouse model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Prostaglandin E2 is increased in amyotrophic lateral sclerosis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

PGE2 receptors rescue motor neurons in a model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Microglia density decreases with age in a mouse model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Early and progressive accumulation of reactive microglia in the Huntington disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Behavioral and anatomical effects of quinolinic acid in the striatum of the hemiparkinsonian rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Combined minocycline plus pyruvate treatment enhances effects of each agent to inhibit inflammation, oxidative damage, and neuronal loss in an excitotoxic animal model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Cyclooxygenase inhibition attenuates 3-nitropropionic acid-induced neurotoxicity in rats: possible antioxidant mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Environmental, pharmacological, and genetic modulation of the HD phenotype in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Minocycline in phenotypic models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Microglial expression of prostaglandin EP3 receptor in excitotoxic lesions in the rat striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Neuroinflammation, microglia and implications for anti-inflammatory treatment in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Hyalinosis cutis et mucosae: a case report

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2012%2F946813

Concurrent blockade of free radical and microsomal prostaglandin E synthase-1-mediated PGE2 production improves safety and efficacy in a mouse model of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

3-Hydroxykynurenine and quinolinate: pathogenic synergism in early grade Huntington's disease?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Prostaglandin A(1) protects striatal neurons against excitotoxic injury in rat striatum

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Cyclooxygenase expression in microglia and neurons in Alzheimer's disease and control brain.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Prostaglandin E2 stimulates amyloid precursor protein gene expression: inhibition by immunosuppressants.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Mice deficient in group IV cytosolic phospholipase A2 are resistant to MPTP neurotoxicity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3385693

Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice

28 November 2018

1 reference

12 December 2020

PGE(2) receptor EP1 renders dopaminergic neurons selectively vulnerable to low-level oxidative stress and direct PGE(2) neurotoxicity

1 reference

12 December 2020

Is prostaglandin E(2) a pathogenic factor in amyotrophic lateral sclerosis?

1 reference

12 December 2020

Purification and characterization of membrane-bound prostaglandin E synthase from bovine heart

1 reference

12 December 2020

Experimental models of multiple sclerosis

1 reference

12 December 2020

Prostaglandins and inhibitors of arachidonate metabolism suppress experimental allergic encephalomyelitis

1 reference

12 December 2020

Microglial activation in chronic neurodegenerative diseases: roles of apoptotic neurons and chronic stimulation

1 reference

12 December 2020

Role of the peroxisome proliferator-activated receptor-gamma (PPAR-gamma) and its natural ligand 15-deoxy-Delta12, 14-prostaglandin J2 in the regulation of microglial functions

1 reference

12 December 2020

Peroxisome proliferator-activated receptor-gamma agonist 15-deoxy-Delta(12,14)-prostaglandin J(2) ameliorates experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Elevated CSF prostaglandin E2 levels in patients with probable AD

1 reference

12 December 2020

Cyclooxygenase expression and prostaglandin levels in central nervous system tissues during the course of chronic relapsing experimental autoimmune encephalomyelitis (EAE)

1 reference

12 December 2020

Prostaglandin E2 downregulates inducible nitric oxide synthase expression in microglia by increasing cAMP levels

1 reference

12 December 2020

1 reference

12 December 2020

Cytosolic phospholipase A2α blockade abrogates disease during the tissue-damage effector phase of experimental autoimmune encephalomyelitis by its action on APCs

1 reference

12 December 2020

Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II

1 reference

12 December 2020

PPARgamma antagonists reverse the inhibition of neural antigen-specific Th1 response and experimental allergic encephalomyelitis by Ciglitazone and 15-deoxy-Delta12,14-prostaglandin J2

1 reference

12 December 2020

Expression of immune system-associated antigens by cells of the human central nervous system: relationship to the pathology of Alzheimer's disease

1 reference

12 December 2020

Inducible nitric oxide synthase expression in activated rat microglial cultures is downregulated by exogenous prostaglandin E2 and by cyclooxygenase inhibitors

1 reference

12 December 2020

Inhibition of cyclooxygenase-2 protects motor neurons in an organotypic model of amyotrophic lateral sclerosis

1 reference

12 December 2020

Prostaglandin D2 as a mediator of allergic asthma

1 reference

12 December 2020

Identifiers

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22778499%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22778499%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22778499%20AND%20SRC:MED&resulttype=core&format=json