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Amyloid-β induced signaling by cellular prion protein and Fyn kinase in Alzheimer disease
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scholarly article
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stated in
PubMed
title
Amyloid-β induced signaling by cellular prion protein and Fyn kinase in Alzheimer disease
(English)
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stated in
PubMed
main subject
cell biology
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infectious disease
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Alzheimer's disease
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based on heuristic
inferred from title
prion protein family
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author name string
Ji Won Um
series ordinal
1
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Crossref
Stephen M. Strittmatter
series ordinal
2
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
2013
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stated in
PubMed
published in
Prion
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stated in
PubMed
volume
7
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stated in
PubMed
issue
1
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PubMed
page(s)
37-41
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PubMed
cites work
Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein
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PubMed Central
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21 March 2017
Regulation of embryonic cell adhesion by the prion protein
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21 March 2017
Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers
1 reference
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PubMed Central
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21 March 2017
Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory
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PubMed Central
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21 March 2017
A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease
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PubMed Central
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21 March 2017
Prions
1 reference
stated in
PubMed Central
reference URL
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21 March 2017
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
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21 March 2017
LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex
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PubMed Central
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21 March 2017
Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models
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PubMed Central
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21 March 2017
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
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PubMed Central
reference URL
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21 March 2017
Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome
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PubMed Central
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21 March 2017
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PubMed Central
reference URL
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7 April 2017
Regulation of NMDA receptor trafficking by amyloid-beta
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PubMed Central
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21 March 2017
Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons
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21 March 2017
Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein
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PubMed Central
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21 March 2017
A specific amyloid-beta protein assembly in the brain impairs memory
1 reference
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PubMed Central
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21 March 2017
Prion Protein Biology
1 reference
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Crossref
reference URL
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22 April 2017
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
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Crossref
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22 April 2017
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PubMed Central
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7 April 2017
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins
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PubMed Central
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7 April 2017
Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function
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PubMed Central
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7 April 2017
Cellular functions regulated by Src family kinases
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PubMed Central
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7 April 2017
Memory impairment in transgenic Alzheimer mice requires cellular prion protein
1 reference
stated in
PubMed Central
reference URL
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25 May 2017
Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease
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PubMed Central
reference URL
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25 May 2017
Aβ neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors
1 reference
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PubMed Central
reference URL
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28 September 2017
The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
1 reference
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PubMed Central
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28 September 2017
Cellular prion protein is essential for oligomeric amyloid-β-induced neuronal cell death
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PubMed Central
reference URL
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28 September 2017
Ablation of cellular prion protein does not ameliorate abnormal neural network activity or cognitive dysfunction in the J20 line of human amyloid precursor protein transgenic mice
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PubMed Central
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28 September 2017
Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites
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PubMed Central
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28 September 2017
Amyloid-beta42 interacts mainly with insoluble prion protein in the Alzheimer brain
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PubMed Central
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28 September 2017
Anti-PrPC monoclonal antibody infusion as a novel treatment for cognitive deficits in an Alzheimer's disease model mouse
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PubMed Central
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28 September 2017
Prion protein and Abeta-related synaptic toxicity impairment
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609048
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28 September 2017
Interaction between human prion protein and amyloid-beta (Abeta) oligomers: role OF N-terminal residues
1 reference
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PubMed Central
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28 September 2017
Many neuronal and behavioral impairments in transgenic mouse models of Alzheimer's disease are independent of caspase cleavage of the amyloid precursor protein
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609048
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28 September 2017
Subcutaneous Nogo receptor removes brain amyloid-beta and improves spatial memory in Alzheimer's transgenic mice
1 reference
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PubMed Central
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28 September 2017
Incidence and predictors of seizures in patients with Alzheimer's disease
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PubMed Central
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28 September 2017
The synaptic localization of NR2B-containing NMDA receptors is controlled by interactions with PDZ proteins and AP-2.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3609048
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28 September 2017
Src kinases: a hub for NMDA receptor regulation
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PubMed Central
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28 September 2017
A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease
1 reference
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PubMed Central
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28 September 2017
The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication
1 reference
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PubMed Central
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31 May 2018
The prion protein as a receptor for amyloid-beta.
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PubMed Central
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31 May 2018
A tail of two src's: mutatis mutandis
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PubMed Central
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31 May 2018
Quantitative assessment of cortical synaptic density in Alzheimer's disease.
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31 May 2018
Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.
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21 January 2018
Unusual spectral energy distribution of a galaxy previously reported to be at redshift 6.68.
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21 January 2018
Altered navigational strategy use and visuospatial deficits in hAPP transgenic mice.
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21 January 2018
Phenotype associated with APP duplication in five families.
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21 January 2018
Oligomerized Abeta25-35 induces increased tyrosine phosphorylation of NMDA receptor subunit 2A in rat hippocampal CA1 subfield
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21 January 2018
Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease.
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Crossref
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21 January 2018
PrPc activation induces neurite outgrowth and differentiation in PC12 cells: role for caveolin-1 in the signal transduction pathway
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21 January 2018
Neuron dysfunction is induced by prion protein with an insertional mutation via a Fyn kinase and reversed by sirtuin activation in Caenorhabditis elegans.
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21 January 2018
PrPc capping in T cells promotes its association with the lipid raft proteins reggie-1 and reggie-2 and leads to signal transduction
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PubMed Central
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28 November 2018
Memory disturbances and temporal lobe epilepsy simulating Alzheimer's disease: a case report.
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28 November 2018
Identifiers
DOI
10.4161/PRI.22212
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PMC publication ID
3609048
1 reference
stated in
PubMed
PubMed publication ID
22987042
1 reference
stated in
PubMed
ResearchGate publication ID
230870958
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