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Caspase-8 as a regulator of tumor cell motility
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scholarly article
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PubMed
title
Caspase-8 as a regulator of tumor cell motility
(English)
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author name string
Graf RP
series ordinal
1
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stated in
PubMed
Keller N
series ordinal
2
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stated in
PubMed
Barbero S
series ordinal
3
1 reference
stated in
PubMed
Stupack D
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4
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PubMed
language of work or name
English
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stated in
PubMed
publication date
February 2014
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PubMed
published in
Current Molecular Medicine
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stated in
PubMed
volume
14
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stated in
PubMed
issue
2
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stated in
PubMed
page(s)
246-54
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PubMed
cites work
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Dynamic regulation of neutrophil survival through tyrosine phosphorylation or dephosphorylation of caspase-8
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Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
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Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
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Mechanism of procaspase-8 activation by c-FLIPL
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Structural and biochemical studies on procaspase-8: new insights on initiator caspase activation
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Rab proteins as membrane organizers
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Mechanisms of caspase activation
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FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex
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cDNA cloning of human calpastatin: sequence homology among human, pig, and rabbit calpastatins
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Caspase-8 serves both apoptotic and nonapoptotic roles
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Ex vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart
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Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
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An essential role of the Jak-2/STAT-3/cytosolic phospholipase A(2) axis in platelet-derived growth factor BB-induced vascular smooth muscle cell motility
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RIP3 mediates the embryonic lethality of caspase-8-deficient mice
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7 April 2017
Structure-function relationships in calpains.
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28 September 2017
Death by caspase dimerization
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28 September 2017
On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics
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28 September 2017
The regulation of cancer cell death and metabolism by extracellular matrix attachment
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28 September 2017
NFκB and ubiquitination: partners in disarming RIPK1-mediated cell death
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28 September 2017
Mapping of vascular ZIP codes by phage display
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Multiple roles for the p85α isoform in the regulation and function of PI3K signalling and receptor trafficking
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28 September 2017
Structure and function of focal adhesions
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28 September 2017
It cuts both ways: reconciling the dual roles of caspase 8 in cell death and survival
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28 September 2017
Proliferative versus apoptotic functions of caspase-8 Hetero or homo: the caspase-8 dimer controls cell fate
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28 September 2017
Control of NF-κB activity by proteolysis
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28 September 2017
A model for sealing plasmalemmal damage in neurons and other eukaryotic cells.
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28 September 2017
Hepatocyte growth factor and its receptor signalling complex as targets in cancer therapy
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28 September 2017
Rab5 mediates caspase-8-promoted cell motility and metastasis
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28 September 2017
Distinct roles for Crk adaptor isoforms in actin reorganization induced by extracellular signals
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28 September 2017
Cellular and nuclear degradation during apoptosis
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28 September 2017
Paclitaxel promotes a caspase 8-mediated apoptosis through death effector domain association with microtubules
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28 September 2017
Critical role for caspase-8 in epidermal growth factor signaling
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28 September 2017
Caspase 8 promotes peripheral localization and activation of Rab5.
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28 September 2017
Non-apoptotic functions of caspase-8.
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28 September 2017
Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration
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28 September 2017
Identification of a critical tyrosine residue in caspase 8 that promotes cell migration
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28 September 2017
Novel noncatalytic role for caspase-8 in promoting SRC-mediated adhesion and Erk signaling in neuroblastoma cells
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28 September 2017
Caspase-8 interacts with the p85 subunit of phosphatidylinositol 3-kinase to regulate cell adhesion and motility
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PubMed Central
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28 September 2017
Targeting the apoptotic machinery in pancreatic cancers using small-molecule antagonists of the X-linked inhibitor of apoptosis protein
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28 September 2017
Targeting caspase 8 to reduce the formation of metastases in neuroblastoma
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28 September 2017
Calpain involvement in the remodeling of cytoskeletal anchorage complexes
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28 September 2017
Src kinase phosphorylates Caspase-8 on Tyr380: a novel mechanism of apoptosis suppression
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28 September 2017
Caspase-8 promotes cell motility and calpain activity under nonapoptotic conditions
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PubMed Central
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28 September 2017
Acquired resistance to TRAIL-induced apoptosis in human ovarian cancer cells is conferred by increased turnover of mature caspase-3.
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28 September 2017
Potentiation of neuroblastoma metastasis by loss of caspase-8.
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28 September 2017
Perturbation of the tumor necrosis factor--related apoptosis-inducing ligand cascade in ovarian cancer: overexpression of FLIPL and deregulation of the functional receptors DR4 and DR5.
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28 September 2017
Proteolysis of cortactin by calpain regulates membrane protrusion during cell migration
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28 September 2017
Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer
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28 September 2017
Calpain-mediated proteolysis of talin regulates adhesion dynamics
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28 September 2017
Interaction of calpastatin with calpain: a review
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28 September 2017
X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells
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28 September 2017
Caspases signal not only apoptosis but also antigen-induced activation in cells of the immune system
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28 September 2017
Mechanisms of CAS substrate domain tyrosine phosphorylation by FAK and Src
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28 September 2017
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28 September 2017
Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.
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28 September 2017
Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis
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PubMed Central
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31 May 2018
Increased expression of Mcl-1 is responsible for the blockage of TRAIL-induced apoptosis mediated by EGF/ErbB1 signaling pathway
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31 May 2018
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.
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31 May 2018
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28 November 2018
Halting neuroblastoma metastasis by controlling integrin-mediated death.
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28 November 2018
Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells
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28 November 2018
Loss of caspase-8 protein expression correlates with unfavorable survival outcome in childhood medulloblastoma.
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28 November 2018
Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.
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28 November 2018
Physical and biochemical regulation of integrin release during rear detachment of migrating cells.
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28 November 2018
Regulation of cell migration by the calcium-dependent protease calpain
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28 November 2018
Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Syncytial fusion of human trophoblast depends on caspase 8
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12 December 2020
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EGFR enhances early healing after cutaneous incisional wounding
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Identifiers
DOI
10.2174/1566524014666140128111951
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3296215
OpenCitations bibliographic resource ID
3296215
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3296215
PMC publication ID
4106798
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3296215
PubMed publication ID
24467204
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3296215
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