(Q27004644)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24734229%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

review article

0 references

title

Role of methylglyoxal in Alzheimer's disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24734229%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

3 references

25 April 2019

7 November 2019

1 reference

7 November 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24734229%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Laura Zambonin

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24734229%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

author name string

Silvana Hrelia

series ordinal

3

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24734229%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

language of work or name

1 reference

9 March 2014

3 references

25 April 2019

7 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24734229%20AND%20SRC:MED&resulttype=core&format=json

BioMed Research International

14 March 2020

published in

4 references

25 April 2019

7 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24734229%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

volume

2014

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24734229%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

page(s)

238485

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24734229%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

14 March 2020

copyright license

2 references

25 April 2019

on focus list of Wikimedia project

7 November 2019

copyright status

copyrighted

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ScienceSource

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Methylglyoxal induces tau hyperphosphorylation via promoting AGEs formation

28 September 2017

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Serum concentration of an inflammatory glycotoxin, methylglyoxal, is associated with increased cognitive decline in elderly individuals

28 September 2017

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28 September 2017

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Advanced glycation endproducts and their pathogenic roles in neurological disorders

28 September 2017

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Tenuigenin protects cultured hippocampal neurons against methylglyoxal-induced neurotoxicity

28 September 2017

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Advanced glycation end products as biomarkers and gerontotoxins - A basis to explore methylglyoxal-lowering agents for Alzheimer's disease?

28 September 2017

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28 September 2017

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Apolipoprotein E: implications for AD neurobiology, epidemiology and risk assessment

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Immunohistochemical study of N-epsilon-carboxymethyl lysine (CML) in human brain: relation to vascular dementia

28 September 2017

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The amyloid-beta precursor protein is phosphorylated via distinct pathways during differentiation, mitosis, stress, and degeneration

28 September 2017

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Methylglyoxal, oxidative stress, and hypertension

28 September 2017

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Methylglyoxal in food and living organisms.

28 September 2017

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Hyperphosphorylation of tau and protein phosphatases in Alzheimer disease

28 September 2017

1 reference

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28 September 2017

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Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells--protection by carbonyl scavengers

28 September 2017

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28 September 2017

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28 September 2017

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Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation

28 September 2017

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Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Involvement of Maillard reactions in Alzheimer disease

28 September 2017

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Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway

28 September 2017

1 reference

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Physiological and pathological implications of semicarbazide-sensitive amine oxidase

28 September 2017

1 reference

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Identification of the binding site of methylglyoxal on glutathione peroxidase: methylglyoxal inhibits glutathione peroxidase activity via binding to glutathione binding sites Arg 184 and 185.

28 September 2017

1 reference

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The role of mitogen-activated protein kinase pathways in Alzheimer's disease

28 September 2017

1 reference

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Amyloid-beta oligomers: their production, toxicity and therapeutic inhibition

28 September 2017

1 reference

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Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress

28 September 2017

1 reference

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Protein glycation, diabetes, and aging

28 September 2017

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Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal cultures

28 September 2017

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Selective vulnerability of spinal motor neurons to reactive dicarbonyl compounds, intermediate products of glycation, in vitro: implication of inefficient glutathione system in spinal motor neurons

28 September 2017

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Methylglyoxal in living organisms: chemistry, biochemistry, toxicology and biological implications

28 September 2017

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Neurotoxicity of methylglyoxal and 3-deoxyglucosone on cultured cortical neurons: synergism between glycation and oxidative stress, possibly involved in neurodegenerative diseases

28 September 2017

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Methylglyoxal modification of protein. Chemical and immunochemical characterization of methylglyoxal-arginine adducts

28 September 2017

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Mammalian plasma and tissue-bound semicarbazide-sensitive amine oxidases: biochemical, pharmacological and toxicological aspects

28 September 2017

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Pharmacology of methylglyoxal: formation, modification of proteins and nucleic acids, and enzymatic detoxification--a role in pathogenesis and antiproliferative chemotherapy.

28 September 2017

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Evidence of neuronal oxidative damage in Alzheimer's disease.

28 September 2017

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Some aspects of the pathophysiology of semicarbazide-sensitive amine oxidase enzymes.

28 September 2017

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Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

28 September 2017

1 reference

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Mechanism for the formation of methylglyoxal from triosephosphates

28 September 2017

1 reference

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The glyoxalase system in health and disease

28 September 2017

1 reference

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Advanced Maillard reaction end products are associated with Alzheimer disease pathology

28 September 2017

1 reference

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Advanced glycation end products contribute to amyloidosis in Alzheimer disease

28 September 2017

1 reference

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Dephosphorylation of Alzheimer's disease abnormally phosphorylated tau by protein phosphatase-2A.

28 September 2017

1 reference

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Metabolism of methylglyoxal in microorganisms

28 September 2017

1 reference

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Charge transfer between amine and carbonyl

28 September 2017

1 reference

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Involvement of a new enzyme, glyoxal oxidase, in extracellular H2O2 production by Phanerochaete chrysosporium

28 September 2017

1 reference

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Oxygen radicals and human disease

28 September 2017

1 reference

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Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966409

104 Methylglyoxal synthase

28 September 2017

1 reference

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Evidence for the generation of excited methylglyoxal in the myoglobin catalyzed oxidation of acetoacetate

28 September 2017

1 reference

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Food derived carbonyl compounds affect basal and stimulated secretion of interleukin-6 and -8 in Caco-2 cells

28 September 2017

1 reference

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Methylglyoxal: a stimulus to neutrophil oxygen radical production in chronic renal failure?

31 May 2018

1 reference

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Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry

31 May 2018

1 reference

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Advanced glycation endproducts co-localize with inducible nitric oxide synthase in Alzheimer's disease

31 May 2018

1 reference

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Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966409

Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966409

Role of the Maillard reaction in aging of tissue proteins. Advanced glycation end product-dependent increase in imidazolium cross-links in human lens proteins.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966409

Oxidative stress hypothesis in Alzheimer's disease

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966409

Are advanced glycation end-products associated with amyloidosis in Alzheimer's disease?

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966409

The metabolism of acetone in rat.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966409

The oxidation of oxyhaemoglobin by glyceraldehyde and other simple monosaccharides.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966409

Redox activation of galactose oxidase: thin-layer electrochemical study

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966409

Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966409

Proteasome inhibition in glyoxal-treated fibroblasts and resistance of glycated glucose-6-phosphate dehydrogenase to 20 S proteasome degradation in vitro.

31 May 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Dicarbonyl intermediates in the maillard reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Potential inplications of endogenous aldehydes in beta-amyloid misfolding, oligomerization and fibrillogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Amyloid-β metabolite sensing: biochemical linking of glycation modification and misfolding

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Age- and stage-dependent accumulation of advanced glycation end products in intracellular deposits in normal and Alzheimer's disease brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Scavenging system efficiency is crucial for cell resistance to ROS-mediated methylglyoxal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Beta-amyloid peptides induce mitochondrial dysfunction and oxidative stress in astrocytes and death of neurons through activation of NADPH oxidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Inflammation-induced alteration of astrocyte mitochondrial dynamics requires autophagy for mitochondrial network maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Methylglyoxal Content in Drinking Coffee as a Cytotoxic Factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Reactivity of thermally treated α-dicarbonyl compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Determination of toxic carbonyl compounds in cigarette smoke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Acetone catabolism by cytochrome P450 2E1: studies with CYP2E1-null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Elevated level of methylglyoxal during diabetic ketoacidosis and its recovery phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Peptide mapping identifies hotspot site of modification in human serum albumin by methylglyoxal involved in ligand binding and esterase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

The advanced glycation end-product N epsilon-(carboxymethyl)lysine level is elevated in cerebrospinal fluid of patients with amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Accumulation of imidazolone, pentosidine and N(epsilon)-(carboxymethyl)lysine in hippocampal CA4 pyramidal neurons of aged human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Protein glycation, oxidation and nitration adduct residues and free adducts of cerebrospinal fluid in Alzheimer's disease and link to cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Possible link between the cognitive dysfunction associated with diabetes mellitus and the neurotoxicity of methylglyoxal

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Has reactive oxygen a role in methylglyoxal toxicity? A study on cultured rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

A H2O2-producing glyoxal oxidase is required for filamentous growth and pathogenicity in Ustilago maydis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Aerobic oxidation of aminoacetone, a threonine catabolite: iron catalysis and coupled iron release from ferritin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Modification of the amino group of guanosine by methylglyoxal and other alpha-ketoaldehydes in the presence of hydrogen peroxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Methylglyoxal-induced fibronectin gene expression through Ras-mediated NADPH oxidase activation in renal mesangial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Glutathione-dependent detoxification of alpha-oxoaldehydes by the glyoxalase system: involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis process

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Advanced glycation end products enhance amyloid precursor protein expression by inducing reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Enhanced binding of advanced glycation endproducts (AGE) by the ApoE4 isoform links the mechanism of plaque deposition in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Age-dependent accumulation of advanced glycosylation end products in human neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Increased protein glycation in cerebrospinal fluid of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Pentosidine and N(epsilon)-(carboxymethyl)-lysine in Alzheimer's disease and vascular dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Neuroscience: Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Oxidative damage is the earliest event in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Alterations in glucose metabolism induce hypothermia leading to tau hyperphosphorylation through differential inhibition of kinase and phosphatase activities: implications for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Role of GSK-3beta activation and alpha7 nAChRs in Abeta(1-42)-induced tau phosphorylation in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase-2A and -2B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Methylglyoxal-bovine serum albumin stimulates tumor necrosis factor alpha secretion in RAW 264.7 cells through activation of mitogen-activating protein kinase, nuclear factor kappaB and intracellular reactive oxygen species formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Methylglyoxal induced activation of murine peritoneal macrophages and surface markers of T lymphocytes in sarcoma-180 bearing mice: involvement of MAP kinase, NF-kappa beta signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Methylglyoxal-induced cytotoxicity in neonatal rat brain: a role for oxidative stress and MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Global budgets of atmospheric glyoxal and methylglyoxal, and implications for formation of secondary organic aerosols

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F238485

Modification and inactivation of human Cu,Zn-superoxide dismutase by methylglyoxal

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966409

Functional organization of microtubule-associated protein tau. Identification of regions which affect microtubule growth, nucleation, and bundle formation in vitro

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966409

Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3966409

1,2-dicarbonyl compounds in commonly consumed foods

28 November 2018

1 reference

12 December 2020

Generation of electronic energy in the myoglobin-catalyzed oxidation of acetoacetate to methylglyoxal

1 reference

12 December 2020

Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with N alpha-acetylarginine, N alpha-acetylcysteine, and N alpha-acetyllysine, and bovine serum albumin

1 reference

12 December 2020

Protein Modification by Methylglyoxal: Chemical Nature and Synthetic Mechanism of a Major Fluorescent Adduct

1 reference

12 December 2020

Advanced Glycation End Products Activate Endothelium Through Signal-Transduction Receptor RAGE

1 reference

12 December 2020

Induction of synthesis and secretion of interleukin 1β in the human monocytic THP-1 cells by human serum albumins modified with methylglyoxal and advanced glycation endproducts

1 reference

12 December 2020

Expression of stress-activated kinases c-Jun N-terminal kinase (SAPK/JNK-P) and p38 kinase (p38-P), and tau hyperphosphorylation in neurites surrounding betaA plaques in APP Tg2576 mice

1 reference

12 December 2020

Stimulation of Suicidal Erythrocyte Death by Methylglyoxal

1 reference

12 December 2020

Effect of pseudophosphorylation and cross-linking by lipid peroxidation and advanced glycation end product precursors on tau aggregation and filament formation

1 reference

12 December 2020

The autoxidation of glyceraldehyde and other simple monosaccharides under physiological conditions catalysed by buffer ions

1 reference

12 December 2020

Glycation--a sweet tempter for neuronal death

1 reference

12 December 2020

Advanced Glycation End Product-Induced Activation of NF-κB is Suppressed by α-Lipoic Acid in Cultured Endothelial Cells

1 reference

12 December 2020

1 reference

12 December 2020

Advanced glycation endproducts in ageing and Alzheimer's disease

1 reference

12 December 2020

The metabolism of aminoacetone to methylglyoxal by semicarbazide-sensitive amine oxidase in human umbilical artery

1 reference

12 December 2020

Methylglyoxal-derived β-carbolines formed from tryptophan and its derivates in the Maillard reaction

1 reference

12 December 2020

Identifiers

DOI

10.1155/2014/238485

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

474199

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24734229%20AND%20SRC:MED&resulttype=core&format=json

OpenCitations bibliographic resource ID

14 March 2020

474199

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24734229%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

PubMed publication ID

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24734229%20AND%20SRC:MED&resulttype=core&format=json