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Mechanisms of mammalian iron homeostasis
scientific article
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scholarly article
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PubMed
title
Mechanisms of mammalian iron homeostasis
(English)
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main subject
iron
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author name string
Kostas Pantopoulos
series ordinal
1
1 reference
stated in
Crossref
Suheel Kumar Porwal
series ordinal
2
1 reference
stated in
Crossref
Alan Tartakoff
series ordinal
3
1 reference
stated in
Crossref
L. Devireddy
series ordinal
4
1 reference
stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
24 July 2012
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stated in
PubMed
published in
Biochemistry
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stated in
PubMed
volume
51
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stated in
PubMed
issue
29
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stated in
PubMed
page(s)
5705-24
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stated in
PubMed
cites work
Regulation of cellular iron metabolism
1 reference
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PubMed Central
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21 March 2017
A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis
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PubMed Central
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21 March 2017
The Fowler syndrome-associated protein FLVCR2 is an importer of heme
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PubMed Central
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21 March 2017
An E3 ligase possessing an iron-responsive hemerythrin domain is a regulator of iron homeostasis
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PubMed Central
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21 March 2017
Control of iron homeostasis by an iron-regulated ubiquitin ligase
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Posttranslational processing of hepcidin in human hepatocytes is mediated by the prohormone convertase furin
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PubMed Central
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21 March 2017
Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance
1 reference
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PubMed Central
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21 March 2017
Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1
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PubMed Central
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21 March 2017
Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption
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PubMed Central
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21 March 2017
Identification of a mammalian mitochondrial porphyrin transporter
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Interleukin-6 induces hepcidin expression through STAT3
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
The Steap proteins are metalloreductases
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Hepcidin mRNA levels in mouse liver respond to inhibition of erythropoiesis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
A mouse model of juvenile hemochromatosis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Identification of a human heme exporter that is essential for erythropoiesis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Regulation of transferrin receptor 2 protein levels by transferrin
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
A spontaneous, recurrent mutation in divalent metal transporter-1 exposes a calcium entry pathway
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Enterobactin: an archetype for microbial iron transport
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity
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PubMed Central
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21 March 2017
Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Hepcidin and iron regulation, 10 years later
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Mutation of a putative mitochondrial iron transporter gene (ABC7) in X-linked sideroblastic anemia and ataxia (XLSA/A)
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Transferrin receptor is necessary for development of erythrocytes and the nervous system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expression
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Expression of hepcidin in hereditary hemochromatosis: evidence for a regulation in response to the serum transferrin saturation and to non-transferrin-bound iron
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
An iron delivery pathway mediated by a lipocalin
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PubMed Central
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21 March 2017
Iron-dependent regulation of the divalent metal ion transporter
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Regulation of iron transport and the role of transferrin
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Mutations in FLVCR1 cause posterior column ataxia and retinitis pigmentosa
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Two to tango: regulation of Mammalian iron metabolism
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
A mammalian siderophore synthesized by an enzyme with a bacterial homolog involved in enterobactin production
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Evidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factors
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Regulation of mitochondrial iron import through differential turnover of mitoferrin 1 and mitoferrin 2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
Identification of a Steap3 endosomal targeting motif essential for normal iron metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
The serine protease TMPRSS6 is required to sense iron deficiency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
Hereditary hemochromatosis protein, HFE, interaction with transferrin receptor 2 suggests a molecular mechanism for mammalian iron sensing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Identification of an intestinal heme transporter
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Cellular iron: ferroportin is the only way out
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
Slc11a2 is required for intestinal iron absorption and erythropoiesis but dispensable in placenta and liver
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
A human mitochondrial ferritin encoded by an intronless gene
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Cloning and characterization of a mammalian proton-coupled metal-ion transporter
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
Scara5 is a ferritin receptor mediating non-transferrin iron delivery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
A heme export protein is required for red blood cell differentiation and iron homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
Mitoferrin is essential for erythroid iron assimilation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
Lipocalin 2-deficient mice exhibit increased sensitivity to Escherichia coli infection but not to ischemia-reperfusion injury
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
Iron-responsive degradation of iron-regulatory protein 1 does not require the Fe-S cluster
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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21 March 2017
A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptake
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
21 March 2017
A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression
1 reference
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PubMed Central
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21 March 2017
Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells
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21 March 2017
nm1054: a spontaneous, recessive, hypochromic, microcytic anemia mutation in the mouse
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21 March 2017
Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2
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21 March 2017
Identification of differentially expressed genes in response to dietary iron deprivation in rat duodenum
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21 March 2017
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
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7 April 2017
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
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7 April 2017
Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietin-mediated increase in erythropoiesis
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28 September 2017
Disorders associated with systemic or local iron overload: from pathophysiology to clinical practice
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28 September 2017
Hepcidin levels and their determinants in different types of myelodysplastic syndromes
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28 September 2017
Non-transferrin bound iron: a key role in iron overload and iron toxicity
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28 September 2017
Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice
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28 September 2017
Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe
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28 September 2017
Regulation of TMPRSS6 by BMP6 and iron in human cells and mice
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28 September 2017
Multiple apoptotic defects in hematopoietic cells from mice lacking lipocalin 24p3
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28 September 2017
Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis
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28 September 2017
Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice
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28 September 2017
The zinc transporter SLC39A14/ZIP14 controls G-protein coupled receptor-mediated signaling required for systemic growth
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28 September 2017
Gastrins, iron homeostasis and colorectal cancer
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28 September 2017
Targeted deletion of the mouse Mitoferrin1 gene: from anemia to protoporphyria.
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28 September 2017
Hypoxia inhibits hepcidin expression in HuH7 hepatoma cells via decreased SMAD4 signaling
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28 September 2017
Hepcidin and disorders of iron metabolism
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28 September 2017
Hereditary hemochromatosis: pathogenesis, diagnosis, and treatment
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28 September 2017
Frataxin and mitochondrial FeS cluster biogenesis.
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28 September 2017
Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol
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28 September 2017
Lysosomal proteolysis is the primary degradation pathway for cytosolic ferritin and cytosolic ferritin degradation is necessary for iron exit.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Chemistry and biology of siderophores
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28 September 2017
Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage
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28 September 2017
SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Genetic and epigenetic silencing of SCARA5 may contribute to human hepatocellular carcinoma by activating FAK signaling
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28 September 2017
Specific iron chelators determine the route of ferritin degradation
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Cross-talk between the mitogen activated protein kinase and bone morphogenetic protein/hemojuvelin pathways is required for the induction of hepcidin by holotransferrin in primary mouse hepatocytes
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
A ferroportin transcript that lacks an iron-responsive element enables duodenal and erythroid precursor cells to evade translational repression.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Hepcidin, the hormone of iron metabolism, is bound specifically to alpha-2-macroglobulin in blood.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Multicellular models of Friedreich ataxia.
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28 September 2017
Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Is the iron donor lipocalin 2 implicated in the pathophysiology of hereditary hemochromatosis?
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Intestinal hypoxia-inducible transcription factors are essential for iron absorption following iron deficiency
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
The role of Dcytb in iron metabolism: an update
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28 September 2017
Ferritins: a family of molecules for iron storage, antioxidation and more.
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28 September 2017
Iron metabolism in the anemia of chronic disease.
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28 September 2017
The hereditary hemochromatosis protein, HFE, inhibits iron uptake via down-regulation of Zip14 in HepG2 cells
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
A cytosolic iron chaperone that delivers iron to ferritin.
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28 September 2017
Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases
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28 September 2017
The transferrin receptor modulates Hfe-dependent regulation of hepcidin expression
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Hfe acts in hepatocytes to prevent hemochromatosis.
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PubMed Central
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28 September 2017
Regulation of iron acquisition and storage: consequences for iron-linked disorders
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28 September 2017
Mitochondrial ferritin expression in adult mouse tissues
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs).
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
The molecular mechanism of hepcidin-mediated ferroportin down-regulation
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Expression of the 1B isoforms of divalent metal transporter (DMT1) is regulated by interaction of NF-Y with a CCAAT-box element near the transcription start site
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Iron-dependent degradation of apo-IRP1 by the ubiquitin-proteasome pathway
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Suppression of hepcidin during anemia requires erythropoietic activity
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Biosynthesis of heme in mammals
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28 September 2017
In vivo tumor growth is inhibited by cytosolic iron deprivation caused by the expression of mitochondrial ferritin
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
How pathogenic bacteria evade mammalian sabotage in the battle for iron
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28 September 2017
The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis.
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28 September 2017
24p3 and its receptor: dawn of a new iron age?
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28 September 2017
TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
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28 September 2017
Divalent metal transporter 1.
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28 September 2017
Intracellular labile iron pools as direct targets of iron chelators: a fluorescence study of chelator action in living cells
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28 September 2017
The molecular basis of ferroportin-linked hemochromatosis
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28 September 2017
First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin.
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28 September 2017
Mouse models to study L-type calcium channel function
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28 September 2017
Hepcidin in iron overload disorders
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28 September 2017
Iron trafficking in the mitochondrion: novel pathways revealed by disease.
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28 September 2017
Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis
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28 September 2017
Diferric transferrin regulates transferrin receptor 2 protein stability
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28 September 2017
Transferrin receptor 1.
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28 September 2017
Labile iron pool: the main determinant of cellular response to oxidative stress
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28 September 2017
Iron, lipocalin, and kidney epithelia
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28 September 2017
Iron metabolism in the reticuloendothelial system
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28 September 2017
Cytokine-mediated regulation of iron transport in human monocytic cells
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28 September 2017
The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.
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28 September 2017
Genetics and assembly line enzymology of siderophore biosynthesis in bacteria
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28 September 2017
The chelatable iron pool in living cells: a methodically defined quantity
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28 September 2017
Mutational analysis of the transferrin receptor reveals overlapping HFE and transferrin binding sites
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 September 2017
The importance of non-transferrin bound iron in disorders of iron metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 September 2017
Beyond the superfamily: the lipocalin receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 September 2017
The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 September 2017
Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 September 2017
Siderophores: structure and function of microbial iron transport compounds
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 September 2017
pH and the recycling of transferrin during receptor-mediated endocytosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 September 2017
Isolation and characterization of a siderophore-like growth factor from mutants of SV40-transformed cells adapted to picolinic acid
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 September 2017
Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
31 May 2018
Transferrin receptor 2 and HFE regulate furin expression via mitogen-activated protein kinase/extracellular signal-regulated kinase (MAPK/Erk) signaling. Implications for transferrin-dependent hepcidin regulation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
31 May 2018
Calcium-channel blockers do not affect iron transport mediated by divalent metal-ion transporter-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
31 May 2018
HIF-2alpha, but not HIF-1alpha, promotes iron absorption in mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
31 May 2018
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
31 May 2018
Evolution of the iron-responsive element
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
31 May 2018
C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
31 May 2018
Transferrin, the transferrin receptor, and the uptake of iron by cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
31 May 2018
Iron homeostasis, oxidative stress, and DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
31 May 2018
Low molecular weight iron-binding factor from mammalian tissue that potentiates bacterial growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
31 May 2018
Conditional disruption of mouse HFE2 gene: maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Liver hemojuvelin protein levels in mice deficient in matriptase-2 (Tmprss6).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Identification of Mutations in SLC40A1 That Affect Ferroportin Function and Phenotype of Human Ferroportin Iron Overload
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Intestinal DMT1 cotransporter is down-regulated by hepcidin via proteasome internalization and degradation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Iron Regulatory Proteins Secure Mitochondrial Iron Sufficiency and Function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Defective bone morphogenic protein signaling underlies hepcidin deficiency in HFE hereditary hemochromatosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Mitochondrial iron metabolism and sideroblastic anemia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Cell-autonomous and systemic context-dependent functions of iron regulatory protein 2 in mammalian iron metabolism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Mechanisms of heme iron absorption: current questions and controversies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
HFE modulates transferrin receptor 2 levels in hepatoma cells via interactions that differ from transferrin receptor 1-HFE interactions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Blunted hepcidin response to oral iron challenge in HFE-related hemochromatosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Targeted disruption of the hepatic transferrin receptor 2 gene in mice leads to iron overload.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
The effects of erythropoetic activity and iron burden on hepcidin expression in patients with thalassemia major.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Complete loss of iron regulatory proteins 1 and 2 prevents viability of murine zygotes beyond the blastocyst stage of embryonic development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Remodeling the regulation of iron metabolism during erythroid differentiation to ensure efficient heme biosynthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Pathogenesis of hyperferritinemia cataract syndrome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Identification of an erythroid active element in the transferrin receptor gene.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Modulation of iron uptake in heart by L-type Ca2+ channel modifiers: possible implications in iron overload.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3572738
retrieved
28 November 2018
Plasma hepcidin is a modest predictor of dietary iron bioavailability in humans, whereas oral iron loading, measured by stable-isotope appearance curves, increases plasma hepcidin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22703180
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Acquired Iron-Deficiency Anemia Caused by an Antibody against the Transferrin Receptor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22703180
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A new role for the transferrin receptor in the release of iron from transferrin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22703180
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
New missense mutation in the human ferrochelatase gene in a family with erythropoietic protoporphyria: functional studies and correlation of genotype and phenotype
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22703180
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Serum hepcidin levels are innately low in HFE-related haemochromatosis but differ between C282Y-homozygotes with elevated and normal ferritin levels
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22703180
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Juvenile hemochromatosis associated with pathogenic mutations of adult hemochromatosis genes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22703180
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
H-ferritin subunit overexpression in erythroid cells reduces the oxidative stress response and induces multidrug resistance properties
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22703180
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Iron homeostasis: insights from genetics and animal models
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22703180
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
T cell, Ig domain, mucin domain-2 gene-deficient mice reveal a novel mechanism for the regulation of Th2 immune responses and airway inflammation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22703180
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Intestinal ferritin H is required for an accurate control of iron absorption
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22703180
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Functional role of DMT1 in transferrin-independent iron uptake by human hepatocyte and hepatocellular carcinoma cell, HLF
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22703180
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1021/BI300752R
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2927715
Fatcat ID
release_ur3xrgykf5eaxpkcbjr2n6rop4
0 references
OpenCitations bibliographic resource ID
2927715
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2927715
PMCID
3572738
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2927715
PubMed ID
22703180
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2927715
ResearchGate publication ID
227162330
0 references
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