(Q27310060)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

title

Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

0 references

1

1 reference

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25 February 2020

Edward C. Schwalbe

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Martine F Roussel

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

author name string

D Kawauchi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

D J Solecki

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

M P Selby

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

P J McKinnon

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

J M Olson

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

J T Hayden

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

R G Grundy

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

D W Ellison

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

D Williamson

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

S Bailey

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

S C Clifford

14

1 reference

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25 February 2020

language of work or name

English

0 references

publication date

22 December 2014

1 reference

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25 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

volume

34

1 reference

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25 February 2020

issue

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

page(s)

4746-4757

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

Molecular subgroups of medulloblastoma: the current consensus

25 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Development and cancer of the cerebellum

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Cerebellum development and medulloblastoma

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Subtypes of medulloblastoma have distinct developmental origins

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Altered neural cell fates and medulloblastoma in mouse patched mutants

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Vav1 fine tunes p53 control of apoptosis versus proliferation in breast cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Medulloblastomics: the end of the beginning

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Vav1 in hematologic neoplasms, a mini review.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Clonal selection drives genetic divergence of metastatic medulloblastoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

An animal model of MYC-driven medulloblastoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

The Hedgehog's tale: developing strategies for targeting cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Rapid diagnosis of medulloblastoma molecular subgroups

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Siah regulation of Pard3A controls neuronal cell adhesion during germinal zone exit

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Guanine nucleotide exchange factors for RhoGTPases: good therapeutic targets for cancer therapy?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Vav3-deficient mice exhibit a transient delay in cerebellar development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

The potential impact of tumour biology on improved clinical practice for medulloblastoma: progress towards biologically driven clinical trials

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Global analysis of the medulloblastoma epigenome identifies disease-subgroup-specific inactivation of COL1A2

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

DNA methylation signatures within the human brain

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Flesh and blood: the story of Vav1, a gene that signals in hematopoietic cells but can be transforming in human malignancies

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

High-throughput DNA methylation profiling using universal bead arrays

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Activation of Vav/Rho GTPase signaling by CXCL12 controls membrane-type matrix metalloproteinase-dependent melanoma cell invasion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Combined genome-wide allelotyping and copy number analysis identify frequent genetic losses without copy number reduction in medulloblastoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Biallelic epigenetic inactivation of the RASSF1A tumor suppressor gene in medulloblastoma development.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Involvement of NH(2)-terminal sequences in the negative regulation of Vav signaling and transforming activity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

A mouse model of the most aggressive subgroup of human medulloblastoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Genomic organization and regulation of the vav proto-oncogene

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386991

Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure

31 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.405

Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.405

Loss of suppressor-of-fused function promotes tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.405

The Smo/Smo model: hedgehog-induced medulloblastoma with 90% incidence and leptomeningeal spread.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.405

Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.405

Genetic alterations in mouse medulloblastomas and generation of tumors de novo from primary cerebellar granule neuron precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.405

TERT promoter mutation and aberrant hypermethylation are associated with elevated expression in medulloblastoma and characterise the majority of non-infant SHH subgroup tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.405

Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.405

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.405

Vav1 and Vav2 play different roles in macrophage migration and cytoskeletal organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.405

21 January 2018

Identifiers

DOI

10.1038/ONC.2014.405

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

25 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25531316%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

PubMed publication ID

25531316

1 reference