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Cerebellum development and medulloblastoma
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scholarly article
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review article
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Europe PubMed Central
title
Cerebellum development and medulloblastoma
(English)
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main subject
cerebellum
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medulloblastoma
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author
Martine F Roussel
object named as
Martine F Roussel
series ordinal
1
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author name string
Mary E Hatten
series ordinal
2
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language of work or name
English
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publication date
2011
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published in
Current Topics in Developmental Biology
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volume
94
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page(s)
235-82
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cites work
Subtypes of medulloblastoma have distinct developmental origins
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29 September 2017
Morphing into cancer: the role of developmental signaling pathways in brain tumor formation
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29 September 2017
Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics
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29 September 2017
The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas
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29 September 2017
Notch1 and notch2 have opposite effects on embryonal brain tumor growth
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29 September 2017
REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma
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29 September 2017
The role of Zic genes in neural development.
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29 September 2017
Medulloblastoma: signalling a change in treatment
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29 September 2017
A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors.
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29 September 2017
Null mutation of DNA strand break-binding molecule poly(ADP-ribose) polymerase causes medulloblastomas in p53(-/-) mice
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29 September 2017
Development of mice expressing a single D-type cyclin.
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29 September 2017
New directions in neuronal migration
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29 September 2017
Medulloblastoma: a problem of developmental biology
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29 September 2017
Medulloblastoma: clinical and biologic aspects
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29 September 2017
The developmental biology of brain tumors.
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29 September 2017
The rhombic lip and early cerebellar development
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29 September 2017
Sonic hedgehog promotes G(1) cyclin expression and sustained cell cycle progression in mammalian neuronal precursors
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29 September 2017
Otx2, Gbx2 and Fgf8 interact to position and maintain a mid-hindbrain organizer
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29 September 2017
Quantitative analysis of cell proliferation and differentiation in the cortex of the postnatal mouse cerebellum
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29 September 2017
Unipolar brush cell: a potential feedforward excitatory interneuron of the cerebellum
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29 September 2017
Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum
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29 September 2017
Neuropsychological consequences of cerebellar tumour resection in children: cerebellar cognitive affective syndrome in a paediatric population
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29 September 2017
Autoregulation and multiple enhancers control Math1 expression in the developing nervous system
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29 September 2017
Targeted deletion of the PEX2 peroxisome assembly gene in mice provides a model for Zellweger syndrome, a human neuronal migration disorder
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29 September 2017
Engrailed, Wnt and Pax genes regulate midbrain--hindbrain development
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29 September 2017
TGFbeta signaling: receptors, transducers, and Mad proteins.
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29 September 2017
Changing patterns of gene expression define four stages of cerebellar granule neuron differentiation
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29 September 2017
Learning and memory in the vestibulo-ocular reflex
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29 September 2017
Mechanisms of neural patterning and specification in the developing cerebellum
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29 September 2017
Neuron-astroglial interactions in vitro and their implications for repair of CNS injury
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29 September 2017
Neuron-glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electronmicroscopic study in Macacus Rhesus
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29 September 2017
Neuronal regulation of astroglial morphology and proliferation in vitro
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29 September 2017
A quantitative study of the human cerebellum with unbiased stereological techniques
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29 September 2017
Cell number and cell density in the cerebellar cortex of man and some other mammals
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29 September 2017
OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas
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PubMed Central
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2 June 2018
Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization
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2 June 2018
Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449
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2 June 2018
Defects in the cerebella of conditional Neurod1 null mice correlate with effective Tg(Atoh1-cre) recombination and granule cell requirements for Neurod1 for differentiation
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2 June 2018
Genetic lineage tracing defines distinct neurogenic and gliogenic stages of ventral telencephalic radial glial development
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2 June 2018
Antagonism between Notch and bone morphogenetic protein receptor signaling regulates neurogenesis in the cerebellar rhombic lip.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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2 June 2018
Identification of ubiquitin ligase substrates by in vitro expression cloning.
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2 June 2018
Gli1 is important for medulloblastoma formation in Ptc1+/- mice
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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2 June 2018
Using Flp-recombinase to characterize expansion of Wnt1-expressing neural progenitors in the mouse.
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2 June 2018
Math1 is essential for genesis of cerebellar granule neurons.
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2 June 2018
Production of a mutation in mouse En-2 gene by homologous recombination in embryonic stem cells.
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2 June 2018
Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome
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2 June 2018
Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells
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27 November 2018
Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma.
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27 November 2018
Large cell/anaplastic medulloblastoma: outcome according to myc status, histopathological, and clinical risk factors.
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27 November 2018
Identification of a SUFU germline mutation in a family with Gorlin syndrome.
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27 November 2018
Differential expression of Notch family members in astrocytomas and medulloblastomas.
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27 November 2018
Ptf1a is a molecular determinant for both glutamatergic and GABAergic neurons in the hindbrain
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
Bone morphogenetic protein 2 opposes Shh-mediated proliferation in cerebellar granule cells through a TIEG-1-based regulation of Nmyc.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
Loss of suppressor-of-fused function promotes tumorigenesis.
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27 November 2018
Genetic alterations in mouse medulloblastomas and generation of tumors de novo from primary cerebellar granule neuron precursors.
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27 November 2018
Progress in the treatment of childhood brain tumors: no room for complacency
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27 November 2018
Molecular markers of neuronal progenitors in the embryonic cerebellar anlage.
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27 November 2018
Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
Expression of Notch and Wnt pathway components and activation of Notch signaling in medulloblastomas from heterozygous patched mice.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
Genetic analyses demonstrate that bone morphogenetic protein signaling is required for embryonic cerebellar development.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
Cognition, emotion and the cerebellum.
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27 November 2018
Epigenetic events in medulloblastoma development.
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27 November 2018
Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
Late Gestation Cerebellar Growth Is Rapid and Impeded by Premature Birth
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
Histopathological and molecular prognostic markers in medulloblastoma: c-myc, N-myc, TrkC, and anaplasia.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
Radial glia serve as neuronal progenitors in all regions of the central nervous system.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors.
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PubMed Central
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27 November 2018
A molecular fingerprint for medulloblastoma.
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27 November 2018
Hemangiosarcomas, medulloblastomas, and other tumors in Ink4c/p53-null mice.
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27 November 2018
An autoradiographic analysis of histogenesis in the mouse cerebellum
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27 November 2018
Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence.
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27 November 2018
The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
Zic1 represses Math1 expression via interactions with the Math1 enhancer and modulation of Math1 autoregulation.
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27 November 2018
Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors
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27 November 2018
DNA ligase IV suppresses medulloblastoma formation.
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27 November 2018
Extending the cerebellar Lugaro cell class.
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27 November 2018
Medulloblastoma growth inhibition by hedgehog pathway blockade
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27 November 2018
BDNF stimulates migration of cerebellar granule cells.
1 reference
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PubMed Central
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27 November 2018
Activated Notch2 signaling inhibits differentiation of cerebellar granule neuron precursors by maintaining proliferation.
1 reference
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PubMed Central
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27 November 2018
The role of the rhombic lip in avian cerebellum development.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
Generation of cerebellar granule neurons in vivo by transplantation of BMP-treated neural progenitor cells.
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PubMed Central
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27 November 2018
lynx1, an endogenous toxin-like modulator of nicotinic acetylcholine receptors in the mammalian CNS.
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27 November 2018
Failure of cerebellar patients to time finger opening precisely causes ball high-low inaccuracy in overarm throws.
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PubMed Central
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27 November 2018
Expansion of CNS precursor pools: a new role for Sonic Hedgehog.
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27 November 2018
FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression.
1 reference
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PubMed Central
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27 November 2018
Distribution of TAG-1 and synaptophysin in the developing cerebellar cortex: relationship to Purkinje cell dendritic development.
1 reference
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PubMed Central
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27 November 2018
Abnormal cerebellar development and foliation in BDNF-/- mice reveals a role for neurotrophins in CNS patterning.
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PubMed Central
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27 November 2018
Embryonic precursor cells from the rhombic lip are specified to a cerebellar granule neuron identity.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3213765
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27 November 2018
Developmental fates and migratory pathways of dividing progenitors in the postnatal rat cerebellum.
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PubMed Central
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27 November 2018
Midbrain development induced by FGF8 in the chick embryo.
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27 November 2018
The mouse zic gene family. Homologues of the Drosophila pair-rule gene odd-paired.
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27 November 2018
Brain lipid-binding protein (BLBP): a novel signaling system in the developing mammalian CNS.
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27 November 2018
H3-thymidine autoradiographic studies on the cell proliferation and differentiation in the external and the internal granular layers of the mouse cerebellum.
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27 November 2018
A new approach to the development of the cerebellum provided by the quail-chick marker system.
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27 November 2018
Expression of neuroD/BETA2 in mitotic and postmitotic neuronal cells during the development of nervous system
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Glial-guided granule neuron migration in vitro: a high-resolution time-lapse video microscopic study
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/21295689
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Incomplete penetrance of the predisposition to medulloblastoma associated with germ-line SUFU mutations
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/21295689
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/B978-0-12-380916-2.00008-5
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1046193
OpenCitations bibliographic resource ID
1046193
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1046193
PMCID
3213765
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1046193
PubMed ID
21295689
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1046193
ResearchGate publication ID
49812013
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