(Q27320024)

26 June 2017

title

Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells (English)

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26 June 2017

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Traver Hart

9

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Christopher Plaisier

object named as

Christopher L Plaisier

15

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Steven M Pollard

object named as

Steven M Pollard

22

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Bruce J Aronow

14

object named as

Bruce J Aronow

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26 June 2017

16

Nitin S Baliga

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26 June 2017

Chad M Toledo

1

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26 June 2017

Yu Ding

2

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Pia Hoellerbauer

3

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Ryan J Davis

4

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26 June 2017

Ryan Basom

5

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26 June 2017

Emily J Girard

6

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26 June 2017

Eunjee Lee

7

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26 June 2017

Philip Corrin

8

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26 June 2017

Hamid Bolouri

10

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26 June 2017

Jerry Davison

11

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26 June 2017

Qing Zhang

12

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26 June 2017

Justin Hardcastle

13

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26 June 2017

Jason Moffat

17

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26 June 2017

Qi Lin

18

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26 June 2017

Xiao-Nan Li

19

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26 June 2017

Do-Hyun Nam

20

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26 June 2017

Jeongwu Lee

21

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26 June 2017

Jun Zhu

23

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26 June 2017

Jeffery J Delrow

24

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Bruce E Clurman

25

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James M Olson

26

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Patrick J Paddison

27

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26 June 2017

language of work or name

English

0 references

publication date

7 December 2015

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26 June 2017

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26 June 2017

volume

13

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26 June 2017

issue

11

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26 June 2017

page(s)

2425-2439

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describes a project that uses

26 June 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4691575/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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21 March 2017

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21 March 2017

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21 March 2017

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ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state

21 March 2017

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Recruitment of factors linking transcription and processing of pre-rRNA to NOR chromatin is UBF-dependent and occurs independent of transcription in human cells

21 March 2017

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21 March 2017

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Genome-scale CRISPR-Cas9 knockout screening in human cells

7 April 2017

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Genetic screens in human cells using the CRISPR-Cas9 system

7 April 2017

1 reference

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7 April 2017

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Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

7 April 2017

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Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

7 April 2017

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7 April 2017

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Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains

28 September 2017

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Emerging function of mTORC2 as a core regulator in glioblastoma: metabolic reprogramming and drug resistance.

28 September 2017

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The Efficacy of the Wee1 Inhibitor MK-1775 Combined with Temozolomide Is Limited by Heterogeneous Distribution across the Blood-Brain Barrier in Glioblastoma

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A

28 September 2017

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Laminin alpha 2 enables glioblastoma stem cell growth

28 September 2017

1 reference

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28 September 2017

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28 September 2017

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28 September 2017

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Quiescence and activation of stem and precursor cell populations in the subependymal zone of the mammalian brain are associated with distinct cellular and extracellular matrix signals

28 September 2017

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28 September 2017

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28 September 2017

1 reference

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28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

Drosophila myt1 is the major cdk1 inhibitory kinase for wing imaginal disc development

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

Myt1 protein kinase is essential for Golgi and ER assembly during mitotic exit

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

Integrative genomic approaches identify IKBKE as a breast cancer oncogene

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

LKB1-dependent signaling pathways

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

Akt/protein kinase B-dependent phosphorylation and inactivation of WEE1Hu promote cell cycle progression at G2/M transition

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

In vivo RNAi screen for BMI1 targets identifies TGF-β/BMP-ER stress pathways as key regulators of neural- and malignant glioma-stem cell homeostasis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

A link between MAP kinase and p34(cdc2)/cyclin B during oocyte maturation: p90(rsk) phosphorylates and inactivates the p34(cdc2) inhibitory kinase Myt1.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

Microhomology-based choice of Cas9 nuclease target sites.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

The glycoglycerolipid 1,2-dipalmitoyl-3-(N-palmitoyl-6'-amino-6'-deoxy-α-d-glucosyl)-sn-glycerol is no inhibitor of the human Myt1 kinase.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

A fluorescence anisotropy-based Myt1 kinase binding assay

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

WEE1 kinase targeting combined with DNA-damaging cancer therapy catalyzes mitotic catastrophe.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4691575

Epidermal growth factor receptor and Ink4a/Arf

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26673326

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A network of genetic events sufficient to convert normal human cells to a tumorigenic state

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26673326

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELREP.2015.11.021

1 reference

26 June 2017

0 references

1 reference