(Q27670677)

5

0 references

Jan Tytgat

6

object named as

Jan Tytgat

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author name string

Marijke Stevens

1

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Steve Peigneur

2

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Natalia Dyubankova

Journal of Biological Chemistry

3

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language of work or name

English

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publication date

7 September 2012

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published in

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volume

287

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issue

37

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page(s)

31382-92

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cites work

Conus venom peptide pharmacology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

A novel µ-conopeptide, CnIIIC, exerts potent and preferential inhibition of NaV1.2/1.4 channels and blocks neuronal nicotinic acetylcholine receptors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Cooccupancy of the outer vestibule of voltage-gated sodium channels by micro-conotoxin KIIIA and saxitoxin or tetrodotoxin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Structure and Sodium Channel Activity of an Excitatory I 1 -Superfamily Conotoxin † , ‡

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

The Xplor-NIH NMR molecular structure determination package

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Refinement of protein structures in explicit solvent

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Structurally diverse μ-conotoxin PIIIA isomers block sodium channel NaV 1.4.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Sodium channel blockers as therapeutic target for treating epilepsy: recent updates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Binding modes of μ-conotoxin to the bacterial sodium channel (NaVAb)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Neurotoxins and their binding areas on voltage-gated sodium channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Lactam-stabilized helical analogues of the analgesic μ-conotoxin KIIIA

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Cyclization of conotoxins to improve their biopharmaceutical properties.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Sodium channel SCN1A and epilepsy: mutations and mechanisms

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

The tetrodotoxin receptor of voltage-gated sodium channels--perspectives from interactions with micro-conotoxins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Genetics and cardiac channelopathies.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Sodium channelopathies of skeletal muscle result from gain or loss of function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

The role of thiols and disulfides on protein stability.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Structure of the analgesic mu-conotoxin KIIIA and effects on the structure and function of disulfide deletion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Pruning nature: Biodiversity-derived discovery of novel sodium channel blocking conotoxins from Conus bullatus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

NMR-based mapping of disulfide bridges in cysteine-rich peptides: application to the mu-conotoxin SxIIIA

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Docking of mu-conotoxin GIIIA in the sodium channel outer vestibule

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Conotoxin modulation of voltage-gated sodium channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Conus venoms: a rich source of novel ion channel-targeted peptides

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Electrostatic and steric contributions to block of the skeletal muscle sodium channel by mu-conotoxin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Clockwise domain arrangement of the sodium channel revealed by (mu)-conotoxin (GIIIA) docking orientation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

A mu-conotoxin-insensitive Na+ channel mutant: possible localization of a binding site at the outer vestibule

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

A new family of conotoxins that blocks voltage-gated sodium channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Conus geographus toxins that discriminate between neuronal and muscle sodium channels.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Structurally minimized mu-conotoxin analogues as sodium channel blockers: implications for designing conopeptide-based therapeutics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

The microI skeletal muscle sodium channel: mutation E403Q eliminates sensitivity to tetrodotoxin but not to mu-conotoxins GIIIA and GIIIB.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Diversity of Conus neuropeptides

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Molecular determinants for the subtype specificity of μ-conotoxin SIIIA targeting neuronal voltage-gated sodium channels

2 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375733

Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375733

Importance of position 8 in μ-conotoxin KIIIA for voltage-gated sodium channel selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375733

Oxidative folding of conotoxins sharing an identical disulfide bridging framework

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375733

Torsion-angle molecular dynamics as a new efficient tool for NMR structure calculation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375733

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375733

Neuronally micro-conotoxins from Conus striatus utilize an alpha-helical motif to target mammalian sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375733

Interactions of key charged residues contributing to selective block of neuronal sodium channels by μ-conotoxin KIIIA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375733

Multiple, distributed interactions of μ-conotoxin PIIIA associated with broad targeting among voltage-gated sodium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375733

Predominant interactions between mu-conotoxin Arg-13 and the skeletal muscle Na+ channel localized by mutant cycle analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375733

Isolation and structure-activity of mu-conotoxin TIIIA, a potent inhibitor of tetrodotoxin-sensitive voltage-gated sodium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375733

Mu-conotoxin SmIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375733

Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375733

Rapid-pulsing artifacts in double-quantum-filtered COSY

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375733

mu-Conotoxin PIIIA, a new peptide for discriminating among tetrodotoxin-sensitive Na channel subtypes.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3438967

Characterization of the neurotoxic constituents of Conus geographus (L) venom

27 November 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.375733

Orientation of -Conotoxin PIIIA in a Sodium Channel Vestibule, Based on Voltage Dependence of Its Binding

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22773842

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Purification, characterization, synthesis, and cloning of the lockjaw peptide from Conus purpurascens venom

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22773842