(Q27727996)

7

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Naoshi Dohmae

5

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author name string

Wataru Shihoya

1

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Tomohiro Nishizawa

2

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Akiko Okuta

3

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Kazutoshi Tani

4

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Yoshinori Fujiyoshi

6

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Tomoko Doi

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

8

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language of work or name

English

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publication date

5 September 2016

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published in

Nature

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volume

537

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issue

7620

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page(s)

363-368

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cites work

1 reference

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Endothelin: 20 years from discovery to therapy

21 January 2018

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Endothelin system: the double-edged sword in health and disease

21 January 2018

1 reference

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Regulation of blood pressure and salt homeostasis by endothelin

21 January 2018

1 reference

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Interaction of endothelin-1 with cloned bovine ETA receptors: biochemical parameters and functional consequences

21 January 2018

1 reference

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Interactions of endothelin receptor subtypes A and B with Gi, Go, and Gq in reconstituted phospholipid vesicles.

21 January 2018

1 reference

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Comparison of human ETA and ETB receptor signalling via G-protein and β-arrestin pathways

21 January 2018

1 reference

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Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis

21 January 2018

1 reference

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Endothelin 1 in cancer: biological implications and therapeutic opportunities

21 January 2018

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New therapeutics that antagonize endothelin: promises and frustrations

21 January 2018

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Macitentan: entry-into-humans study with a new endothelin receptor antagonist

21 January 2018

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Ambrisentan, a non-peptide endothelin receptor antagonist

21 January 2018

1 reference

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Endothelin@25 - new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12

21 January 2018

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Molecular signatures of G-protein-coupled receptors

21 January 2018

1 reference

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Structure of the agonist-bound neurotensin receptor

21 January 2018

1 reference

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Structural biology. Crystal structure of the chemokine receptor CXCR4 in complex with a viral chemokine

21 January 2018

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Protein-protein interactions: general trends in the relationship between binding affinity and interfacial buried surface area

21 January 2018

1 reference

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The crystal structure of human endothelin

21 January 2018

1 reference

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Distributed computing and NMR constraint-based high-resolution structure determination: applied for bioactive Peptide endothelin-1 to determine C-terminal folding

21 January 2018

1 reference

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Conformational isomerism of endothelin in acidic aqueous media: a quantitative NOESY analysis

21 January 2018

1 reference

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Structural determinants for selective recognition of peptide ligands for endothelin receptor subtypes ETA and ETB.

21 January 2018

1 reference

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Alanine scan of endothelin: Importance of aromatic residues

21 January 2018

1 reference

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[Ala1,3,11,15]endothelin-1 analogs with ETB agonistic activity.

21 January 2018

1 reference

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Identification of Receptor Binding and Activation Sites in Endothelin-1 by Use of Site-Directed Mutagenesis

21 January 2018

1 reference

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Activation and allosteric modulation of a muscarinic acetylcholine receptor

21 January 2018

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Structural prerequisites for G-protein activation by the neurotensin receptor

21 January 2018

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Structural insights into µ-opioid receptor activation

21 January 2018

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Crystal structure of the β2 adrenergic receptor-Gs protein complex

21 January 2018

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The dynamic process of β(2)-adrenergic receptor activation

21 January 2018

1 reference

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Propagation of conformational changes during μ-opioid receptor activation

21 January 2018

1 reference

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Allosteric sodium in class A GPCR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

The structural basis of agonist-induced activation in constitutively active rhodopsin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Structure of an agonist-bound human A2A adenosine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Characterization of endothelin receptors ETA and ETB expressed in COS cells

21 January 2018

1 reference

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Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form

21 January 2018

1 reference

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A fluorescence-detection size-exclusion chromatography-based thermostability assay for membrane protein precrystallization screening

21 January 2018

1 reference

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Palmitoylation of human endothelinB. Its critical role in G protein coupling and a differential requirement for the cytoplasmic tail by G protein subtypes.

21 January 2018

1 reference

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

21 January 2018

1 reference

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Modified T4 Lysozyme Fusion Proteins Facilitate G Protein-Coupled Receptor Crystallogenesis

21 January 2018

1 reference

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Crystallizing membrane proteins using lipidic mesophases

21 January 2018

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21 January 2018

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Phasercrystallographic software

21 January 2018

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Features and development of Coot

21 January 2018

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 January 2018

1 reference

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MolProbity: all-atom structure validation for macromolecular crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Characterization of human endothelin B receptor and mutant receptors expressed in insect cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

[Lys(-2)-Arg(-1)]endothelin-1 solution structure by two-dimensional 1H-NMR: possible involvement of electrostatic interactions in native disulfide bridge formation and in biological activity decrease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Deciphering key features in protein structures with the new ENDscript server

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE19319

Pathophysiological role of endothelin revealed by the first orally active endothelin receptor antagonist

21 January 2018

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International Union of Pharmacology. XXIX. Update on endothelin receptor nomenclature

21 January 2018

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12 December 2020

Molecular cloning and characterization of the major endothelin receptor subtype in porcine cerebellum

1 reference

12 December 2020

Purification of an endothelin receptor from human placenta

1 reference

12 December 2020

Aspirin and sodium salicylate inhibit endothelin ETA receptors by an allosteric type of mechanism

1 reference

12 December 2020

Human endothelin receptor ETB. Amino acid sequence requirements for super stable complex formation with its ligand

1 reference

12 December 2020

D-amino acid scan of endothelin: importance of amino acids adjacent to cysteinyl residues in isomeric selectivity

1 reference

12 December 2020

Thermostabilization of the Human Endothelin Type B Receptor

1 reference

12 December 2020

Endothelins: molecular biology, biochemistry, pharmacology, physiology, and pathophysiology.

1 reference

12 December 2020

The quasi-irreversible nature of endothelin binding and G protein-linked signaling in cardiac myocytes.

1 reference

12 December 2020

Endothelin-1 analogues substituted at both position 18 and 19: highly potent endothelin antagonists with no selectivity for either receptor subtype ETA or ETB

1 reference

12 December 2020

Regulation and intracellular trafficking pathways of the endothelin receptors

1 reference

12 December 2020

Structure-activity relationship of endothelin: importance of charged groups

1 reference

12 December 2020

Lysine 182 of endothelin B receptor modulates agonist selectivity and antagonist affinity: evidence for the overlap of peptide and non-peptide ligand binding sites

1 reference

12 December 2020