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Erythropoietin and mTOR: A "One-Two Punch" for Aging-Related Disorders Accompanied by Enhanced Life Expectancy
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review article
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Europe PubMed Central
title
Erythropoietin and mTOR: A "One-Two Punch" for Aging-Related Disorders Accompanied by Enhanced Life Expectancy
(English)
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PubMed
main subject
life expectancy
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erythropoietin
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inferred from title
author name string
Maiese K
series ordinal
1
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language of work or name
English
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PubMed
publication date
2016
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published in
Current neurovascular research
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PubMed
volume
13
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PubMed
issue
4
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PubMed
page(s)
329-340
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29 September 2017
Methylene blue-induced neuronal protective mechanism against hypoxia-reoxygenation stress
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29 September 2017
Proline-rich AKT substrate of 40-kDa (PRAS40) in the pathophysiology of cancer
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29 September 2017
Aβ peptide secretion is reduced by Radix Polygalae-induced autophagy via activation of the AMPK/mTOR pathway
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29 September 2017
A possible role for AMP-activated protein kinase activated by metformin and AICAR in human granulosa cells
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29 September 2017
A genome-wide scan reveals important roles of DNA methylation in human longevity by regulating age-related disease genes.
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29 September 2017
Regulatory effects of caffeic acid phenethyl ester on neuroinflammation in microglial cells
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29 September 2017
Growth factor treatment to overcome Alzheimer's dysfunctional signaling
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29 September 2017
Programming apoptosis and autophagy with novel approaches for diabetes mellitus
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29 September 2017
Pharmacologic agents targeting autophagy
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29 September 2017
Conophylline protects cells in cellular models of neurodegenerative diseases by inducing mammalian target of rapamycin (mTOR)-independent autophagy
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29 September 2017
Protective effect of erythropoietin against myocardial injury in rats with sepsis and its underlying mechanisms
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29 September 2017
Crosstalk Between Endoplasmic Reticulum Stress, Oxidative Stress, and Autophagy: Potential Therapeutic Targets for Acute CNS Injuries
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29 September 2017
Protein tyrosine phosphatases in mast cell signaling
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29 September 2017
Anti-inflammatory agents to treat or prevent type 2 diabetes, metabolic syndrome and cardiovascular disease
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29 September 2017
Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease
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29 September 2017
Modulating mTOR in aging and health
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29 September 2017
Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis
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29 September 2017
Overnutrition, mTOR signaling, and cardiovascular diseases
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29 September 2017
Melatonin regulates aging and neurodegeneration through energy metabolism, epigenetics, autophagy and circadian rhythm pathways
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29 September 2017
Erythropoietin, a novel versatile player regulating energy metabolism beyond the erythroid system
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29 September 2017
Diet control to achieve euglycemia induces significant loss of heart and liver weight via increased autophagy compared with ad libitum diet in diabetic rats
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29 September 2017
Longitudinal follow-up of autophagy and inflammation in brain of APPswePS1dE9 transgenic mice
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29 September 2017
Association between early administration of high-dose erythropoietin in preterm infants and brain MRI abnormality at term-equivalent age.
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29 September 2017
Resveratrol and cardiovascular health--promising therapeutic or hopeless illusion?
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29 September 2017
The role of erythropoietin stimulating agents in anemic patients with heart failure: solved and unresolved questions
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29 September 2017
Taking aim at Alzheimer's disease through the mammalian target of rapamycin
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29 September 2017
Alpha-lipoic acid as a pleiotropic compound with potential therapeutic use in diabetes and other chronic diseases
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29 September 2017
Adiponectin stimulates autophagy and reduces oxidative stress to enhance insulin sensitivity during high-fat diet feeding in mice.
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29 September 2017
Effect of erythropoietin and transfusion threshold on neurological recovery after traumatic brain injury: a randomized clinical trial
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29 September 2017
Systemic treatment with erythropoietin protects the neurovascular unit in a rat model of retinal neurodegeneration
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29 September 2017
An activator of mTOR inhibits oxLDL-induced autophagy and apoptosis in vascular endothelial cells and restricts atherosclerosis in apolipoprotein E⁻/⁻ mice
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29 September 2017
AMPK is involved in mediation of erythropoietin influence on metabolic activity and reactive oxygen species production in white adipocytes
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29 September 2017
Erythropoietin action in stress response, tissue maintenance and metabolism
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29 September 2017
Glucagon-like peptide-1 analog-mediated protection against cholesterol-induced apoptosis via mammalian target of rapamycin activation in pancreatic βTC-6 cells -1mTORβTC-6.
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29 September 2017
From neurogenesis to neuroprotection in the epilepsy: signalling by erythropoietin
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29 September 2017
Omega-3 Fatty acids could alleviate the risks of traumatic brain injury - a mini review.
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29 September 2017
ADSC therapy in neurodegenerative disorders.
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29 September 2017
Compound K protects pancreatic islet cells against apoptosis through inhibition of the AMPK/JNK pathway in type 2 diabetic mice and in MIN6 β-cells
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29 September 2017
Therapeutic effects of pharmacologically induced hypothermia against traumatic brain injury in mice
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29 September 2017
Hematological parameters, and hematopoietic growth factors: EPO and IL-3 in response to whole-body cryostimulation (WBC) in military academy students
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29 September 2017
Acute metformin preconditioning confers neuroprotection against focal cerebral ischaemia by pre-activation of AMPK-dependent autophagy
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29 September 2017
Human choriogonadotropin and epoetin alfa in acute ischemic stroke patients (REGENESIS-LED trial).
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29 September 2017
Autophagy in the endocrine glands
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29 September 2017
Neuroprotective effects of erythropoiesis-stimulating agents in term and preterm neonates
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29 September 2017
Multi-Target-Directed Ligands and other Therapeutic Strategies in the Search of a Real Solution for Alzheimer's Disease
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29 September 2017
Excitotoxic glutamate insults block autophagic flux in hippocampal neurons
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29 September 2017
Insulin-like growth factor promotes cardiac lineage induction in vitro by selective expansion of early mesoderm.
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29 September 2017
SIRT1 positively regulates autophagy and mitochondria function in embryonic stem cells under oxidative stress
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29 September 2017
Metformin modulates hyperglycaemia-induced endothelial senescence and apoptosis through SIRT1.
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29 September 2017
Rheb GTPase regulates β-secretase levels and amyloid β generation
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29 September 2017
Involvement of interleukin-1β in the autophagic process of microglia: relevance to Alzheimer's disease
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29 September 2017
Role of protein tyrosine phosphatases in the modulation of insulin signaling and their implication in the pathogenesis of obesity-linked insulin resistance
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29 September 2017
Exploiting mTOR signaling: a novel translatable treatment strategy for traumatic optic neuropathy?
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29 September 2017
Age-dependent astroglial vulnerability to hypoxia and glutamate: the role for erythropoietin
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29 September 2017
High-dose erythropoietin in acute ST-segment elevation myocardial infarction: a meta-analysis of randomized controlled trials
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29 September 2017
Antidepressant-like effects of erythropoietin: a focus on behavioural and hippocampal processes
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29 September 2017
PPARα and Sirt1 mediate erythropoietin action in increasing metabolic activity and browning of white adipocytes to protect against obesity and metabolic disorders
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29 September 2017
Erythropoietin protects epithelial cells from excessive autophagy and apoptosis in experimental neonatal necrotizing enterocolitis
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29 September 2017
Rapamycin, Autophagy, and Alzheimer's Disease
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29 September 2017
Prevention of diabetes-induced cardiovascular complications upon treatment with antioxidants
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29 September 2017
mTOR: on target for novel therapeutic strategies in the nervous system
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29 September 2017
Tuberous sclerosis protein 2 (TSC2) modulates CCN4 cytoprotection during apoptotic amyloid toxicity in microglia
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29 September 2017
Evidence of synergistic/additive effects of sildenafil and erythropoietin in enhancing survival and migration of hypoxic endothelial cells.
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29 September 2017
Erythropoietin modulates autophagy signaling in the developing rat brain in an in vivo model of oxygen-toxicity
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29 September 2017
A Critical Kinase Cascade in Neurological Disorders: PI 3-K, Akt, and mTOR.
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29 September 2017
The human glucagon-like peptide-1 analogue liraglutide regulates pancreatic beta-cell proliferation and apoptosis via an AMPK/mTOR/P70S6K signaling pathway
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29 September 2017
Novel directions for diabetes mellitus drug discovery
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29 September 2017
Nitrosative stress plays an important role in Wnt pathway activation in diabetic retinopathy
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29 September 2017
Activation of Wnt/β-catenin pathway by exogenous Wnt1 protects SH-SY5Y cells against 6-hydroxydopamine toxicity
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29 September 2017
PRAS40 is an integral regulatory component of erythropoietin mTOR signaling and cytoprotection
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29 September 2017
Wnt1 inducible signaling pathway protein 1 (WISP1) targets PRAS40 to govern β-amyloid apoptotic injury of microglia
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29 September 2017
Autophagy contributes to retardation of cardiac growth in diabetic rats
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29 September 2017
GATA-binding protein 4 (GATA-4) and T-cell acute leukemia 1 (TAL1) regulate myogenic differentiation and erythropoietin response via cross-talk with Sirtuin1 (Sirt1)
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29 September 2017
Fasting glucose, obesity, and coronary artery calcification in community-based people without diabetes
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29 September 2017
Mammalian target of rapamycin signaling in diabetic cardiovascular disease
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29 September 2017
WISP1 (CCN4) autoregulates its expression and nuclear trafficking of β-catenin during oxidant stress with limited effects upon neuronal autophagy
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29 September 2017
Autophagy induced by resveratrol prevents human prion protein-mediated neurotoxicity
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29 September 2017
GLP1-derived nonapeptide GLP1(28-36)amide protects pancreatic β-cells from glucolipotoxicity
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29 September 2017
Prevention of β-amyloid degeneration of microglia by erythropoietin depends on Wnt1, the PI 3-K/mTOR pathway, Bad, and Bcl-xL.
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29 September 2017
Autophagy in hypoxia-ischemia induced brain injury.
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29 September 2017
Neuroprotective properties of Loranthus parasiticus aqueous fraction against oxidative stress-induced damage in NG108-15 cells
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29 September 2017
PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations
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29 September 2017
SIRT1: new avenues of discovery for disorders of oxidative stress
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29 September 2017
Translating cell survival and cell longevity into treatment strategies with SIRT1
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29 September 2017
From oxygen to erythropoietin: relevance of hypoxia for retinal development, health and disease
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29 September 2017
Platelet dysfunction in vascular pathologies and how can it be treated
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29 September 2017
Erythropoietin and Wnt1 govern pathways of mTOR, Apaf-1, and XIAP in inflammatory microglia
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29 September 2017
MG-2477, a new tubulin inhibitor, induces autophagy through inhibition of the Akt/mTOR pathway and delayed apoptosis in A549 cells
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29 September 2017
Erythropoietin levels are not independently associated with malaria-attributable severe disease in Mozambican children
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29 September 2017
Proline-rich Akt substrate of 40kDa (PRAS40): a novel downstream target of PI3k/Akt signaling pathway.
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29 September 2017
Erythropoietin mediated bone formation is regulated by mTOR signaling
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29 September 2017
Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mTOR signaling.
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29 September 2017
Erythropoietin employs cell longevity pathways of SIRT1 to foster endothelial vascular integrity during oxidant stress
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29 September 2017
Erythropoietin as a novel brain and kidney protective agent.
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29 September 2017
Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice
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29 September 2017
Intravenous erythropoietin in patients with ST-segment elevation myocardial infarction: REVEAL: a randomized controlled trial
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29 September 2017
The PI3K/Akt/mTOR pathway mediates retinal progenitor cell survival under hypoxic and superoxide stress
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29 September 2017
EPO relies upon novel signaling of Wnt1 that requires Akt1, FoxO3a, GSK-3β, and β-catenin to foster vascular integrity during experimental diabetes
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29 September 2017
mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways
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29 September 2017
Diabetes as a chronic metabolic stressor: causes, consequences and clinical complications
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29 September 2017
SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model
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29 September 2017
Applications and biomonitoring issues of recombinant erythropoietins for doping control
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29 September 2017
Erythropoietin prevention trial of coronary restenosis and cardiac remodeling after ST-elevated acute myocardial infarction (EPOC-AMI): a pilot, randomized, placebo-controlled study
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29 September 2017
New strategies for Alzheimer's disease and cognitive impairment
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29 September 2017
The inhibitor of phagocytosis, O-phospho-L-serine, suppresses Müller glia proliferation and cone cell regeneration in the light-damaged zebrafish retina
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29 September 2017
Wnt1, FoxO3a, and NF-kappaB oversee microglial integrity and activation during oxidant stress
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29 September 2017
Early apoptotic vascular signaling is determined by Sirt1 through nuclear shuttling, forkhead trafficking, bad, and mitochondrial caspase activation
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29 September 2017
Novel avenues of drug discovery and biomarkers for diabetes mellitus
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29 September 2017
Oxidative stress: Biomarkers and novel therapeutic pathways
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29 September 2017
A novel mTOR activating protein protects dopamine neurons against oxidative stress by repressing autophagy related cell death
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29 September 2017
FoxO3a governs early microglial proliferation and employs mitochondrial depolarization with caspase 3, 8, and 9 cleavage during oxidant induced apoptosis
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29 September 2017
The vitamin nicotinamide: translating nutrition into clinical care
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29 September 2017
Downregulation of cell survival signalling pathways and increased cell damage in hydrogen peroxide-treated human renal proximal tubular cells by alpha-erythropoietin
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29 September 2017
Life span extension and neuronal cell protection by Drosophila nicotinamidase
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29 September 2017
Erythropoietin and oxidative stress
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29 September 2017
The TSC1-TSC2 complex is required for proper activation of mTOR complex 2
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29 September 2017
Erythropoietin: elucidating new cellular targets that broaden therapeutic strategies
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29 September 2017
Triple play: promoting neurovascular longevity with nicotinamide, WNT, and erythropoietin in diabetes mellitus
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29 September 2017
The Wnt signaling pathway: aging gracefully as a protectionist?
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29 September 2017
Raves and risks for erythropoietin
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29 September 2017
Vascular injury during elevated glucose can be mitigated by erythropoietin and Wnt signaling
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29 September 2017
Mechanistic insights into diabetes mellitus and oxidative stress
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29 September 2017
Erythropoietin involves the phosphatidylinositol 3-kinase pathway, 14-3-3 protein and FOXO3a nuclear trafficking to preserve endothelial cell integrity
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29 September 2017
Oxidative stress in the brain: novel cellular targets that govern survival during neurodegenerative disease
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29 September 2017
New avenues of exploration for erythropoietin
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29 September 2017
Erythropoietin on a tightrope: balancing neuronal and vascular protection between intrinsic and extrinsic pathways
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29 September 2017
Erythropoietin in the brain: can the promise to protect be fulfilled?
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29 September 2017
Erythropoietin: cytoprotection in vascular and neuronal cells
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29 September 2017
Erythropoietin fosters both intrinsic and extrinsic neuronal protection through modulation of microglia, Akt1, Bad, and caspase-mediated pathways
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29 September 2017
Angiogenesis and plasticity: role of erythropoietin in vascular systems
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29 September 2017
Hematopoietic factor erythropoietin fosters neuroprotection through novel signal transduction cascades
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29 September 2017
Early detection of undiagnosed diabetes mellitus: a US perspective
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29 September 2017
Effect of active oxygen radicals on protein and carbohydrate moieties of recombinant human erythropoietin
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29 September 2017
The role of carbohydrate in recombinant human erythropoietin
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29 September 2017
MicroRNAs and SIRT1: A Strategy for Stem Cell Renewal and Clinical Development?
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2 June 2018
mTOR: Driving apoptosis and autophagy for neurocardiac complications of diabetes mellitus
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2 June 2018
Elevated serum concentrations of erythropoietin after xenon anaesthesia in cardiac surgery: secondary analysis of a randomized controlled trial
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2 June 2018
Erythropoietin attenuates advanced glycation endproducts-induced toxicity of Schwann cells in vitro
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2 June 2018
Tract-based spatial statistics to assess the neuroprotective effect of early erythropoietin on white matter development in preterm infants.
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2 June 2018
Effects of Salidroside on cobalt chloride-induced hypoxia damage and mTOR signaling repression in PC12 cells
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2 June 2018
Pure red-cell aplasia and antierythropoietin antibodies in patients treated with recombinant erythropoietin
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2 June 2018
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2 June 2018
Erythropoietin for Out-of-Hospital Cardiac Arrest: Growing Together or Apart?
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27 November 2018
WISP1 is a novel adipokine linked to metabolic parameters in gestational diabetes mellitus.
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27 November 2018
Caffeic acid attenuates oxidative stress, learning and memory deficit in intra-cerebroventricular streptozotocin induced experimental dementia in rats.
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27 November 2018
Effect of Autoantibodies to Erythropoietin Receptor in Systemic Lupus Erythematosus with Biopsy-proven Lupus Nephritis.
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27 November 2018
The Akt/mTOR/p70S6K Pathway Is Involved in the Neuroprotective Effect of Erythropoietin on Hypoxic/Ischemic Brain Injury in a Neonatal Rat Model.
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27 November 2018
Effect and mechanism of fuzhisan and donepezil on the sirtuin 1 pathway and amyloid precursor protein metabolism in PC12 cells.
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27 November 2018
A Therapeutic Insight of Niacin and Coenzyme Q10 Against Diabetic Encephalopathy in Rats.
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27 November 2018
Hyperglycemia-induced inflammation caused down-regulation of 8-oxoG-DNA glycosylase levels in murine macrophages is mediated by oxidative-nitrosative stress-dependent pathways
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27 November 2018
Resveratrol Ameliorates the Components of Hepatic Inflammation and Apoptosis in a Rat Model of Streptozotocin-Induced Diabetes.
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27 November 2018
Downstream modulation of extrinsic apoptotic pathway in streptozotocin-induced Alzheimer's dementia in rats: Erythropoietin versus curcumin.
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27 November 2018
mTOR inhibition by rapamycin protects against deltamethrin-induced apoptosis in PC12 Cells
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27 November 2018
Erythropoietin and Its Derivates Modulate Mitochondrial Dysfunction after Diffuse Traumatic Brain Injury.
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27 November 2018
Reduced silent information regulator 1 signaling exacerbates myocardial ischemia-reperfusion injury in type 2 diabetic rats and the protective effect of melatonin.
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retrieved
27 November 2018
Influence of age-related learning and memory capacity of mice: different effects of a high and low caloric diet.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Effect of caloric restriction on the SIRT1/mTOR signaling pathways in senile mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
SIRT1 and stem cells: In the forefront with cardiovascular disease, neurodegeneration and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Characterization of traumatic brain injury in human brains reveals distinct cellular and molecular changes in contusion and pericontusion.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
The administration of erythropoietin attenuates kidney injury induced by ischemia/reperfusion with increased activation of Wnt/β-catenin signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Ameliorating the effect of astragaloside IV on learning and memory deficit after chronic cerebral hypoperfusion in rats.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Tet1-mediated DNA demethylation regulates neuronal cell death induced by oxidative stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Rapamycin ester analog CCI-779/Temsirolimus alleviates tau pathology and improves motor deficit in mutant tau transgenic mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
WISP1 is a novel adipokine linked to inflammation in obesity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Beta-asarone attenuates amyloid beta-induced autophagy via Akt/mTOR pathway in PC12 cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
μ-Opioid receptor attenuates Aβ oligomers-induced neurotoxicity through mTOR signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
AMPK activation ameliorates Alzheimer's disease-like pathology and spatial memory impairment in a streptozotocin-induced Alzheimer's disease model in rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Erythropoietin priming improves the vasculogenic potential of G-CSF mobilized human peripheral blood mononuclear cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Delphinidin-3-glucoside protects human umbilical vein endothelial cells against oxidized low-density lipoprotein-induced injury by autophagy upregulation via the AMPK/SIRT1 signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Early molecular and behavioral response to lipopolysaccharide in the WAG/Rij rat model of absence epilepsy and depressive-like behavior, involves interplay between AMPK, AKT/mTOR pathways and neuroinflammatory cytokine release.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
High glucose condition induces autophagy in endothelial progenitor cells contributing to angiogenic impairment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Biosimilar epoetin in elderly patients with low-risk myelodysplastic syndromes improves anemia, quality of life, and brain function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Characterization of Gcf2/Lrrfip1 in experimental cerebral ischemia and its role as a modulator of Akt, mTOR and β-catenin signaling pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Temsirolimus promotes autophagic clearance of amyloid-β and provides protective effects in cellular and animal models of Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Rapamycin induces of protective autophagy in vascular endothelial cells exposed to oxygen-glucose deprivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Safety and efficacy of recombinant human erythropoietin treatment of non-motor symptoms in Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
EGB1212 post-treatment ameliorates hippocampal CA1 neuronal death and memory impairment induced by transient global cerebral ischemia/reperfusion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Puerarin ameliorates oxidative stress in a rodent model of traumatic brain injury
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
The AKT/mTOR pathway mediates neuronal protective effects of erythropoietin in sepsis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Ferulic acid attenuates focal cerebral ischemia-induced decreases in p70S6 kinase and S6 phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Arctigenin effectively ameliorates memory impairment in Alzheimer's disease model mice targeting both β-amyloid production and clearance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Erythropoietin combined with ACE inhibitor prevents heart remodeling in 5/6 nephrectomized rats independently of blood pressure and kidney function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Therapeutic targets for cancer: current concepts with PI 3-K, Akt, & mTOR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Epidermal growth factor receptor transactivation is necessary for glucagon-like peptide-1 to protect PC12 cells from apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Anxiety correlates to decreased blood and prefrontal cortex IGF-1 levels in streptozotocin induced diabetes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Endogenous erythropoietin from astrocyte protects the oligodendrocyte precursor cell against hypoxic and reoxygenation injury.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
A pilot study of chronic, low-dose epoetin-{beta} following percutaneous coronary intervention suggests safety, feasibility, and efficacy in patients with symptomatic ischaemic heart failure.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Survival, neuron-like differentiation and functionality of mesenchymal stem cells in neurotoxic environment: the critical role of erythropoietin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Knockout of the tumor necrosis factor a receptor 1 gene can up-regulate erythropoietin receptor during myocardial ischemia-reperfusion injury in mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Specific activation of mTORC1 by Rheb G-protein in vitro involves enhanced recruitment of its substrate protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Brain erythropoietin receptor expression in Alzheimer disease and mild cognitive impairment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Erythropoietin concentrations and neurodevelopmental outcome in preterm infants.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Apaf-1, Bcl-xL, cytochrome c, and caspase-9 form the critical elements for cerebral vascular protection by erythropoietin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Erythropoietin prevents early and late neuronal demise through modulation of Akt1 and induction of caspase 1, 3, and 8.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Erythropoietin is a novel vascular protectant through activation of Akt1 and mitochondrial modulation of cysteine proteases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5079807
retrieved
27 November 2018
Physicochemical and biological comparison of recombinant human erythropoietin with human urinary erythropoietin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27488211
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Regeneration in the nervous system with erythropoietin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27488211
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27488211
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The effect of hemin-induced oxidative stress on erythropoietin production in HepG2 cells
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27488211
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Experimental acute myocardial infarction in rats: HIF-1α, caspase-3, erythropoietin and erythropoietin receptor expression and the cardioprotective effects of two different erythropoietin doses
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27488211
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Erythropoietin, forkhead proteins, and oxidative injury: biomarkers and biology
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27488211
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Death in the United States, 2011
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27488211
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Adult neural precursors isolated from post mortem brain yield mostly neurons: An erythropoietin-dependent process
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27488211
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Stabilization of human recombinant erythropoietin through interactions with the highly branched N-glycans
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27488211
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Erythropoietin
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/27488211
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.2174/1567202613666160729164900
0 references
PMCID
5079807
1 reference
stated in
PubMed
PubMed ID
27488211
1 reference
stated in
PubMed
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