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Dysregulation of autophagy and mitochondrial function in Parkinson's disease
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PubMed
review article
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Europe PubMed Central
title
Dysregulation of autophagy and mitochondrial function in Parkinson's disease
(English)
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stated in
PubMed
main subject
Parkinson's disease
1 reference
based on heuristic
inferred from title
autophagy
0 references
author name string
Bao Wang
series ordinal
1
1 reference
stated in
Crossref
Neeta Abraham
series ordinal
2
1 reference
stated in
Crossref
Guodong Gao
series ordinal
3
1 reference
stated in
Crossref
Qian Yang
series ordinal
4
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
31 October 2016
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stated in
PubMed
published in
Translational Neurodegeneration
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stated in
Crossref
volume
5
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stated in
PubMed
issue
1
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page(s)
19
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PubMed
exact match
https://scigraph.springernature.com/pub.10.1186/s40035-016-0065-1
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cites work
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The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy
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Genetics of Parkinson's disease
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Cdk5-mediated phosphorylation of endophilin B1 is required for induced autophagy in models of Parkinson's disease
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Glutamate excitotoxicity in neurons triggers mitochondrial and endoplasmic reticulum accumulation of Parkin, and, in the presence of N-acetyl cysteine, mitophagy
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Role of chaperone mediated autophagy (CMA) in the degradation of misfolded N-CoR protein in non-small cell lung cancer (NSCLC) cells
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PINK1 loss-of-function mutations affect mitochondrial complex I activity via NdufA10 ubiquinone uncoupling
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Identification of a candidate therapeutic autophagy-inducing peptide
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20 March 2017
Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1
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The role of autophagy in neurodegenerative disease
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Autophagy and metabolism
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Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
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Essential control of mitochondrial morphology and function by chaperone-mediated autophagy through degradation of PARK7
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The Parkinson's Disease-Associated Mutation LRRK2-G2019S Impairs Synaptic Plasticity in Mouse Hippocampus
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Posttranslational Modifications and Clearing of α-Synuclein Aggregates in Yeast
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Destabilization of survival factor MEF2D mRNA by neurotoxin in models of Parkinson's disease
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Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy
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Parkin and PINK1: much more than mitophagy
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α-Synuclein ubiquitination and novel therapeutic targets for Parkinson's disease.
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Recent advances in Parkinson’s disease genetics.
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Neuroprotective function of DJ-1 in Parkinson's disease
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Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan
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TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity
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The PINK1-Parkin pathway promotes both mitophagy and selective respiratory chain turnover in vivo
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AF-6 is a positive modulator of the PINK1/parkin pathway and is deficient in Parkinson's disease.
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29 September 2017
Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction
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Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin
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Sustained expression of PGC-1α in the rat nigrostriatal system selectively impairs dopaminergic function.
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29 September 2017
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Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death
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29 September 2017
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29 September 2017
Hsc70 protein interaction with soluble and fibrillar alpha-synuclein
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29 September 2017
Molecular machinery of macroautophagy and its deregulation in diseases.
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29 September 2017
Toxin models of mitochondrial dysfunction in Parkinson's disease.
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29 September 2017
Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein
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29 September 2017
Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts
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29 September 2017
Direct regulation of complex I by mitochondrial MEF2D is disrupted in a mouse model of Parkinson disease and in human patients
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29 September 2017
DJ-1 regulation of mitochondrial function and autophagy through oxidative stress
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29 September 2017
Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease
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29 September 2017
The Parkinson disease protein α-synuclein inhibits autophagy
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29 September 2017
Mitophagy: the latest problem for Parkinson's disease
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29 September 2017
Does autophagy take a front seat in lifespan extension?
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29 September 2017
Astaxanthin protects against MPTP/MPP+-induced mitochondrial dysfunction and ROS production in vivo and in vitro
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29 September 2017
DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
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29 September 2017
Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity
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α-Synuclein: membrane interactions and toxicity in Parkinson's disease
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29 September 2017
G2019S LRRK2 mutant fibroblasts from Parkinson's disease patients show increased sensitivity to neurotoxin 1-methyl-4-phenylpyridinium dependent of autophagy.
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Quercetin up-regulates mitochondrial complex-I activity to protect against programmed cell death in rotenone model of Parkinson's disease in rats
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2 June 2018
The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway
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2 June 2018
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2 June 2018
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DJ-1 protects dopaminergic neurons against rotenone-induced apoptosis by enhancing ERK-dependent mitophagy
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21 January 2018
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DJ-1, a cancer and Parkinson's disease associated protein, regulates autophagy through JNK pathway in cancer cells
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21 January 2018
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iPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis.
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Molecular insights into Parkinson's disease
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Lysosomal alterations in peripheral blood mononuclear cells of Parkinson's disease patients
1 reference
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1186/S40035-016-0065-1
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2736845
Dimensions Publication ID
1017871594
0 references
OpenCitations bibliographic resource ID
2736845
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2736845
PMCID
5087125
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2736845
PubMed ID
27822367
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2736845
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