(Q28215807)

1

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Eve Diefenbach

2

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Prerna Badhwar

3

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Sarah Woodruff

4

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Therese M Becker

5

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Robert J Rooney

6

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Richard F Kefford

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

14 February 2003

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published in

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volume

278

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issue

7

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page(s)

4981-9

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cites work

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Germline p16 mutations in familial melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Haplotype analysis and age estimation of the 113insR CDKN2A founder mutation in Swedish melanoma families

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

A melanoma-associated germline mutation in exon 1beta inactivates p14ARF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

E1A signaling to p53 involves the p19(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

p14ARF links the tumour suppressors RB and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Tumor surveillance via the ARF-p53 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Differential requirement for p19ARF in the p53-dependent arrest induced by DNA damage, microtubule disruption, and ribonucleotide depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

p53-independent functions of the p19(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

p19ARF targets certain E2F species for degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Human ARF binds E2F1 and inhibits its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

The human tumor suppressor arf interacts with spinophilin/neurabin II, a type 1 protein-phosphatase-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Human ARF protein interacts with topoisomerase I and stimulates its activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

The p14ARF tumor suppressor protein facilitates nucleolar sequestration of hypoxia-inducible factor-1alpha (HIF-1alpha ) and inhibits HIF-1-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Pex19p dampens the p19ARF-p53-p21WAF1 tumor suppressor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

CARF is a novel protein that cooperates with mouse p19ARF (human p14ARF) in activating p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

The adenovirus E1A-regulated transcription factor E4F is generated from the human homolog of nuclear factor phiAP3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Mutational analysis of p50E4F suggests that DNA binding activity is mediated through an alternative structure in a zinc finger domain that is regulated by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Cyclin A is a mediator of p120E4F-dependent cell cycle arrest in G1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Adenovirus E1A-regulated transcription factor p120E4F inhibits cell growth and induces the stabilization of the cdk inhibitor p21WAF1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Suppression of E1A-mediated transformation by the p50E4F transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

p53 is involved in the p120E4F-mediated growth arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

pRB binds to and modulates the transrepressing activity of the E1A-regulated transcription factor p120E4F

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Two arginine rich domains in the p14ARF tumour suppressor mediate nucleolar localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Defining the molecular basis of Arf and Hdm2 interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

The INK4a/ARF network in tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Multiple interacting domains contribute to p14ARF mediated inhibition of MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

p14(ARF) regulates E2F activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

ARF function does not require p53 stabilization or Mdm2 relocalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Transcriptional regulation of the human tumor suppressor p14(ARF) by E2F1, E2F2, E2F3, and Sp1-like factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Germline Mutations of the CDKN2 Gene in UK Melanoma Families

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group [published erratum appears in Hum Mol Genet 1998 May;7(5):941]

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Germline mutation of ARF in a melanoma kindred

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Mutations in theINK4a/ARFMelanoma Susceptibility Locus Functionally Impair p14ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

CDKN2A (P16(INK4a)) and CDK4 mutation analysis in 131 Australian melanoma probands: effect of family history and multiple primary melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Contribution of two independent MDM2-binding domains in p14(ARF) to p53 stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200

Multiple abnormalities of the p16INK4a-pRb regulatory pathway in cultured melanoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M210978200