(Q28240316)

English

Cytohesin binder and regulator augments T cell receptor-induced nuclear factor of activated T Cells.AP-1 activation through regulation of the JNK pathway

scientific article (publication date: 21 July 2006)

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scholarly article

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Cytohesin binder and regulator augments T cell receptor-induced nuclear factor of activated T Cells.AP-1 activation through regulation of the JNK pathway (English)

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author name string

Qian Chen

1

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Alan Coffey

2

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Sylvain G Bourgoin

3

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Massimo Gadina

4

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language of work or name

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publication date

21 July 2006

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Journal of Biological Chemistry

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281

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29

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19985-94

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Gene expression elicited by NFAT in the presence or absence of cooperative recruitment of Fos and Jun.

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The N-terminal coiled coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with the scaffolding protein CASP

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p21ras and calcineurin synergize to regulate the nuclear factor of activated T cells

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A functional T-cell receptor signaling pathway is required for p95vav activity

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The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase

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PI3K in lymphocyte development, differentiation and activation

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Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways.

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Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

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Phosphorylation and recruitment of Syk by immunoreceptor tyrosine-based activation motif-based phosphorylation of tamalin

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T cell antigen receptor signal transduction

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Vav-family proteins in T-cell signalling

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Structure and function of vav

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Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte

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Identifiers

10.1074/JBC.M601629200

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