(Q28243492)

7

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author name string

Hiroaki Okazaki

1

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Fumiko Tazoe

2

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Sachiko Okazaki

3

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Naoyuki Isoo

4

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Kazuhisa Tsukamoto

5

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Motohiro Sekiya

6

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Yoko Iizuka

8

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Ken Ohashi

9

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Tetsuya Kitamine

10

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Ryu-Ichi Tozawa

11

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Toshihiro Inaba

12

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Hiroaki Yagyu

13

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Mitsuyo Okazaki

14

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Hitoshi Shimano

15

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Hiroyuki Arai

17

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Ryo-Zo Nagai

18

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Takashi Kadowaki

19

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Jun-Ichi Osuga

20

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Shun Ishibashi

Journal of Lipid Research

21

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language of work or name

English

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publication date

September 2006

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published in

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volume

47

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issue

9

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page(s)

1950-8

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cites work

Regulation of the mevalonate pathway

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Feedback regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in livers of mice treated with mevinolin, a competitive inhibitor of the reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Statin-associated myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Multiple sequence elements are involved in the transcriptional regulation of the human squalene synthase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Lipid-lowering properties of TAK-475, a squalene synthase inhibitor, in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Embryonic lethality and defective neural tube closure in mice lacking squalene synthase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Early embryonic lethality caused by targeted disruption of the 3-hydroxy-3-methylglutaryl-CoA reductase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Liver-directed gene transfer and prolonged expression of three major human ApoE isoforms in ApoE-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Elimination of cholesterol ester from macrophage foam cells by adenovirus-mediated gene transfer of hormone-sensitive lipase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Decreased lipid synthesis in livers of mice with disrupted Site-1 protease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Supernatant protein factor, which stimulates the conversion of squalene to lanosterol, is a cytosolic squalene transfer protein and enhances cholesterol biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

YM‐53601, a novel squalene synthase inhibitor, suppresses lipogenic biosynthesis and lipid secretion in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Regulation of isoprenoid/cholesterol biosynthesis in cells from mevalonate kinase-deficient patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200

Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M600224-JLR200