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TIGAR is required for efficient intestinal regeneration and tumorigenesis
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
23726973
retrieved
31 January 2017
title
TIGAR is required for efficient intestinal regeneration and tumorigenesis
(English)
1 reference
stated in
PubMed
PubMed ID
23726973
retrieved
31 January 2017
main subject
Trp53 induced glycolysis regulatory phosphatase
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GOA release 2020-03-11
author
Dimitris Athineos
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2
object named as
Dimitris Athineos
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PubMed
PubMed ID
23726973
retrieved
31 January 2017
Pearl Lee
object named as
Pearl Lee
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3
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Karen Blyth
object named as
Karen Blyth
series ordinal
8
0 references
Owen J Sansom
object named as
Owen J. Sansom
series ordinal
9
0 references
Karen Vousden
series ordinal
10
object named as
Karen H. Vousden
1 reference
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PubMed
PubMed ID
23726973
retrieved
31 January 2017
author name string
Eric C. Cheung
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
23726973
retrieved
31 January 2017
Rachel A. Ridgway
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
23726973
retrieved
31 January 2017
Wendy Lambie
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
23726973
retrieved
31 January 2017
Colin Nixon
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
23726973
retrieved
31 January 2017
Douglas Strathdee
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7
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PubMed
PubMed ID
23726973
retrieved
31 January 2017
language of work or name
English
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publication date
10 June 2013
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PubMed
PubMed ID
23726973
retrieved
31 January 2017
published in
Developmental Cell
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stated in
PubMed
PubMed ID
23726973
retrieved
31 January 2017
volume
25
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stated in
PubMed
PubMed ID
23726973
retrieved
31 January 2017
issue
5
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stated in
PubMed
PubMed ID
23726973
retrieved
31 January 2017
page(s)
463–477
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stated in
PubMed
PubMed ID
23726973
retrieved
31 January 2017
cites work
Mitochondrial localization of TIGAR under hypoxia stimulates HK2 and lowers ROS and cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Links between metabolism and cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Inhibition of the MUC1-C oncoprotein induces multiple myeloma cell death by down-regulating TIGAR expression and depleting NADPH
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Regulation of cancer cell metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Analysis of mouse models of cytochrome c oxidase deficiency owing to mutations in Sco2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Modulation of intracellular ROS levels by TIGAR controls autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Understanding the Warburg effect: the metabolic requirements of cell proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Crypt stem cells as the cells-of-origin of intestinal cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Structural and biochemical studies of TIGAR (TP53-induced glycolysis and apoptosis regulator)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Brick by brick: metabolism and tumor cell growth
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Identification of stem cells in small intestine and colon by marker gene Lgr5
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Mitochondrial manganese-superoxide dismutase expression in ovarian cancer: role in cell proliferation and response to oxidative stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
The mitochondrial SDHD gene is required for early embryogenesis, and its partial deficiency results in persistent carotid body glomus cell activation with full responsiveness to hypoxia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
17 March 2017
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
7 April 2017
p53 and metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
7 April 2017
Tumor cell metabolism: cancer's Achilles' heel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
7 April 2017
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
7 April 2017
Production of large amounts of hydrogen peroxide by human tumor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
7 April 2017
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Tp53-induced glycolysis and apoptosis regulator (TIGAR) protects glioma cells from starvation-induced cell death by up-regulating respiration and improving cellular redox homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Functional metabolic screen identifies 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 as an important regulator of prostate cancer cell survival.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Mitochondrial thiols in antioxidant protection and redox signaling: distinct roles for glutathionylation and other thiol modifications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Regulatory role of p53 in cancer metabolism via SCO2 and TIGAR in human breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Metabolic regulation of Drosophila apoptosis through inhibitory phosphorylation of Dronc
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Glutamine addiction: a new therapeutic target in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
The molecular determinants of de novo nucleotide biosynthesis in cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Immortalized mouse epithelial cell models to study the role of apoptosis in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
p53: new roles in metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Regulation and Physiological Functions of Malic Enzymes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
29 September 2017
Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
3 June 2018
Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
3 June 2018
Clinicopathologic study of dextran sulfate sodium experimental murine colitis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
3 June 2018
Target cells for the cytotoxic effects of carcinogens in the murine small bowel
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
3 June 2018
RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
27 November 2018
Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3682186
retrieved
27 November 2018
Apoptosis in small intestinal epithelial from p53-null mice: evidence for a delayed, p53-independent G2/M-associated cell death after gamma-irradiation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23726973
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23726973
retrieved
12 December 2020
based on heuristic
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Identifiers
DOI
10.1016/J.DEVCEL.2013.05.001
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1841282
OpenCitations bibliographic resource ID
1841282
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1841282
PMCID
3682186
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1841282
PubMed ID
23726973
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1841282
ResearchGate publication ID
237003163
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