(Q28587122)

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Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function

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scholarly article

1 reference

Europe PubMed Central

24 June 2017

Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function (English)

1 reference

Europe PubMed Central

24 June 2017

Protein tyrosine phosphatase, non-receptor type 6

1 reference

GOA release 2020-03-11

Megakaryocyte and platelet inhibitory receptor G6b

1 reference

GOA release 2020-03-11

Protein tyrosine phosphatase, non-receptor type 11

1 reference

GOA release 2020-03-11

Alexandra Mazharian

object named as

Alexandra Mazharian

1

0 references

Steve P. Watson

object named as

Steve P Watson

6

0 references

author name string

Jun Mori

2

1 reference

Europe PubMed Central

24 June 2017

Ying-Jie Wang

3

1 reference

Europe PubMed Central

24 June 2017

Silke Heising

4

1 reference

Europe PubMed Central

24 June 2017

Benjamin G Neel

5

1 reference

Europe PubMed Central

24 June 2017

Yotis A Senis

7

1 reference

Europe PubMed Central

24 June 2017

language of work or name

0 references

publication date

18 March 2013

1 reference

Europe PubMed Central

24 June 2017

1 reference

Europe PubMed Central

24 June 2017

121

1 reference

Europe PubMed Central

24 June 2017

4205-4220

1 reference

Europe PubMed Central

24 June 2017

20

1 reference

Europe PubMed Central

24 June 2017

Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

17 March 2017

The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

17 March 2017

CEACAM1 negatively regulates platelet-collagen interactions and thrombus growth in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

17 March 2017

Immunoreceptor tyrosine-based inhibition motifs: a quest in the past and future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

17 March 2017

Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

17 March 2017

Integrins: dynamic scaffolds for adhesion and signaling in platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

17 March 2017

A TREM family member, TLT-1, is found exclusively in the alpha-granules of megakaryocytes and platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

17 March 2017

Crystal structure of human protein-tyrosine phosphatase SHP-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

17 March 2017

Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

17 March 2017

Crystal structure of the tyrosine phosphatase SHP-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

17 March 2017

Spatial constraints on the recognition of phosphoproteins by the tandem SH2 domains of the phosphatase SH-PTP2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

17 March 2017

Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

Leukocyte-associated immunoglobulin-like receptor-1 is expressed on human megakaryocytes and negatively regulates the maturation of primary megakaryocytic progenitors and cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

Cytoskeletal mechanics of proplatelet maturation and platelet release.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

Critical role of Src-Syk-PLC{gamma}2 signaling in megakaryocyte migration and thrombopoiesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

Regulation of megakaryocyte maturation and platelet formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

Differential dephosphorylation of the FcRgamma immunoreceptor tyrosine-based activation motif tyrosines with dissimilar potential for activating Syk.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

Nonreceptor protein-tyrosine phosphatases in immune cell signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

A novel role for PECAM-1 in megakaryocytokinesis and recovery of platelet counts in thrombocytopenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

A comprehensive proteomics and genomics analysis reveals novel transmembrane proteins in human platelets and mouse megakaryocytes including G6b-B, a novel immunoreceptor tyrosine-based inhibitory motif protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

SHP-2 activates signaling of the nuclear factor of activated T cells to promote skeletal muscle growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

Rac1 is essential for platelet lamellipodia formation and aggregate stability under flow.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

Src Homology Region 2-Containing Protein Tyrosine Phosphatase-2 (SHP-2) Can Play a Direct Role in the Inhibitory Function of Killer Cell Ig-Like Receptors in Human NK Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

Regulation of early events in integrin signaling by protein tyrosine phosphatase SHP-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

Insulin signaling in mice expressing reduced levels of Syp.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

29 September 2017

Differentially regulated GPVI ectodomain shedding by multiple platelet-expressed proteinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

3 June 2018

Critical role for ERK1/2 in bone marrow and fetal liver-derived primary megakaryocyte differentiation, motility, and proplatelet formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

3 June 2018

Role of the p110delta PI 3-kinase in integrin and ITAM receptor signalling in platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

3 June 2018

Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

3 June 2018

Proteomic analysis of integrin alphaIIbbeta3 outside-in signaling reveals Src-kinase-independent phosphorylation of Dok-1 and Dok-3 leading to SHIP-1 interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

27 November 2018

B cell-specific deletion of protein-tyrosine phosphatase Shp1 promotes B-1a cell development and causes systemic autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

27 November 2018

An Shp2/SFK/Ras/Erk signaling pathway controls trophoblast stem cell survival.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

27 November 2018

Adhesion of human and mouse platelets to collagen under shear: a unifying model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

27 November 2018

SHP-2 regulates the phosphatidylinositide 3'-kinase/Akt pathway and suppresses caspase 3-mediated apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

27 November 2018

Convulxin binds to native, human glycoprotein Ib alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

27 November 2018

Platelet endothelial cell adhesion molecule-1 signaling inhibits the activation of human platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

27 November 2018

Platelet endothelial cell adhesion molecule-1 is a negative regulator of platelet-collagen interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

27 November 2018

The SH2 tyrosine phosphatase shp2 is required for mammalian limb development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

27 November 2018

Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

27 November 2018

Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3656453

27 November 2018

Evidence of a Role for SHP-1 in Platelet Activation by the Collagen Receptor Glycoprotein VI

1 reference

https://pubmed.ncbi.nlm.nih.gov/23509158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/23509158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potent stimulation of SH-PTP2 phosphatase activity by simultaneous occupancy of both SH2 domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/23509158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo biotinylation demonstrates that reticulated platelets are the youngest platelets in circulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23509158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of actin stress fiber assembly and proplatelet formation by alpha2beta1 integrin and GPVI in human megakaryocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23509158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23509158

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1182/BLOOD-2012-08-449272

1 reference

Europe PubMed Central

24 June 2017

release_hiz4mtfwh5f63edwaa7dvespwu

1 reference

https://api.fatcat.wiki/v0/release/hiz4mtfwh5f63edwaa7dvespwu

24 November 2022

based on heuristic

mapped directly with Wikidata item

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1 reference

Europe PubMed Central

24 June 2017

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