(Q28589635)

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Impaired NF-kappa B activation and increased production of tumor necrosis factor alpha in transgenic mice expressing keratin K10 in the basal layer of the epidermis

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PubMed publication ID

31 January 2017

Impaired NF-kappa B activation and increased production of tumor necrosis factor alpha in transgenic mice expressing keratin K10 in the basal layer of the epidermis (English)

1 reference

PubMed publication ID

31 January 2017

1 reference

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Jesus M. Paramio

6

object named as

Jesús M. Paramio

1 reference

PubMed publication ID

31 January 2017

object named as

Paloma Perez

2

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author name string

Mirentxu Santos

1

1 reference

PubMed publication ID

31 January 2017

Carmen Segrelles

3

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PubMed publication ID

31 January 2017

Sergio Ruiz

4

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PubMed publication ID

31 January 2017

José L. Jorcano

5

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PubMed publication ID

31 January 2017

language of work or name

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publication date

11 April 2003

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PubMed publication ID

31 January 2017

Journal of Biological Chemistry

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PubMed publication ID

31 January 2017

278

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PubMed publication ID

31 January 2017

15

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PubMed publication ID

31 January 2017

13422–13430

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PubMed publication ID

31 January 2017

Intermediate filaments: structure, dynamics, function, and disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Intermediate filaments in disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Human keratin diseases: the increasing spectrum of disease and subtlety of the phenotype-genotype correlation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Modulation of cell proliferation by cytokeratins K10 and K16

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

The expression of keratin k10 in the basal layer of the epidermis inhibits cell proliferation and prevents skin tumorigenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Functional roles of Akt signaling in mouse skin tumorigenesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

AKT plays a central role in tumorigenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

PKB/AKT: functional insights from genetic models

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Roles of Akt/PKB and IKK complex in constitutive induction of NF-kappaB in hepatocellular carcinomas of transforming growth factor alpha/c-myc transgenic mice.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

The PTEN tumor suppressor protein inhibits tumor necrosis factor-induced nuclear factor kappa B activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Induction of NF-kappaB by the Akt/PKB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Protein kinase B regulates T lymphocyte survival, nuclear factor kappaB activation, and Bcl-X(L) levels in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

It's got you covered. NF-kappaB in the epidermis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Alterations in NF-κB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-κB

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Increased expression of p50-NF-kappaB and constitutive activation of NF-kappaB transcription factors during mouse skin carcinogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Role of phosphorylated p50-NF-kappaB in the ultraviolet response of mouse skin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Limb and skin abnormalities in mice lacking IKKalpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

IKK1-deficient mice exhibit abnormal development of skin and skeleton

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

IKKalpha controls formation of the epidermis independently of NF-kappaB.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Calcium regulation of growth and differentiation of mouse epidermal cells in culture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Overexpression of RelA in transgenic mouse thymocytes: specific increase in levels of the inhibitor protein I kappa B alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Early Lethality, Functional NF-κB Activation, and Increased Sensitivity to TNF-Induced Cell Death in TRAF2-Deficient Mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

NF-kappaB at the crossroads of life and death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Regulation of the human TNF promoter by the transcription factor Ets.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Engagement of tumor necrosis factor (TNF) receptor 1 leads to ATF-2- and p38 mitogen-activated protein kinase-dependent TNF-alpha gene expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Stimulus-specific assembly of enhancer complexes on the tumor necrosis factor alpha gene promoter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

A lipopolysaccharide-specific enhancer complex involving Ets, Elk-1, Sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Keratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Changes in keratin gene expression during terminal differentiation of the keratinocyte

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Insulin-like growth factor-I inhibits the stress-activated protein kinase/c-Jun N-terminal kinase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

Cachexia and graft-vs.-host-disease-type skin changes in keratin promoter-driven TNF alpha transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

TRAF2 Is Essential for JNK but Not NF-κB Activation and Regulates Lymphocyte Proliferation and Survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208170200

21 January 2018

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