(Q28602324)

3

object named as

Bin Chen

0 references

Zhiyong Lu

6

object named as

Zhiyong Lu

0 references

author name string

Jiao Li

1

0 references

Si Zheng

2

0 references

S Joshua Swamidass

Briefings in Bioinformatics

5

0 references

language of work or name

English

0 references

publication date

January 2016

0 references

published in

0 references

volume

17

0 references

issue

1

0 references

page(s)

2-12

0 references

cites work

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LabeledIn: cataloging labeled indications for human drugs

17 March 2017

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Validating drug repurposing signals using electronic health records: a case study of metformin associated with reduced cancer mortality

17 March 2017

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Identification of drug combinations containing imatinib for treatment of BCR-ABL+ leukemias

17 March 2017

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Construction of drug network based on side effects and its application for drug repositioning

17 March 2017

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Drug repositioning by kernel-based integration of molecular structure, molecular activity, and phenotype data

17 March 2017

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SWEETLEAD: an in silico database of approved drugs, regulated chemicals, and herbal isolates for computer-aided drug discovery

17 March 2017

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The challenges, advantages and future of phenome-wide association studies

17 March 2017

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MicroRNAs: regulators of cancer metastasis and epithelial-mesenchymal transition (EMT)

17 March 2017

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PubTator: a web-based text mining tool for assisting biocuration

17 March 2017

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Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties

17 March 2017

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Assessing drug target association using semantic linked data

17 March 2017

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Systematic drug repositioning based on clinical side-effects

17 March 2017

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PREDICT: a method for inferring novel drug indications with application to personalized medicine

17 March 2017

1 reference

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PubMed and beyond: a survey of web tools for searching biomedical literature

17 March 2017

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Drug-induced regulation of target expression

17 March 2017

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How to improve R&D productivity: the pharmaceutical industry's grand challenge

17 March 2017

1 reference

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Understanding PubMed user search behavior through log analysis

17 March 2017

1 reference

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Predicting new molecular targets for known drugs

17 March 2017

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

17 March 2017

1 reference

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NCBI GEO: mining millions of expression profiles--database and tools

17 March 2017

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DAVID: Database for Annotation, Visualization, and Integrated Discovery

17 March 2017

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17 March 2017

The Protein Data Bank

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A side effect resource to capture phenotypic effects of drugs

17 March 2017

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Genetics of rheumatoid arthritis contributes to biology and drug discovery

7 April 2017

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Genomic responses in mouse models poorly mimic human inflammatory diseases

7 April 2017

1 reference

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Systematic identification of genomic markers of drug sensitivity in cancer cells

7 April 2017

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The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

7 April 2017

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7 April 2017

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Towards drug repositioning: a unified computational framework for integrating multiple aspects of drug similarity and disease similarity

7 April 2017

1 reference

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Scaling drug indication curation through crowdsourcing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Characteristics of drug combination therapy in oncology by analyzing clinical trial data on ClinicalTrials.gov

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Computational and experimental advances in drug repositioning for accelerated therapeutic stratification

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Deciphering miRNA transcription factor feed-forward loops to identify drug repurposing candidates for cystic fibrosis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

MicroRNAs as predictive biomarkers and therapeutic targets in prostate cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Large-scale integration of small molecule-induced genome-wide transcriptional responses, Kinome-wide binding affinities and cell-growth inhibition profiles reveal global trends characterizing systems-level drug action

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

A New Method for Computational Drug Repositioning Using Drug Pairwise Similarity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

A phenome-guided drug repositioning through a latent variable model

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Genomic responses in mouse models greatly mimic human inflammatory diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Recent advances in drug repositioning for the discovery of new anticancer drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Systematic drug repurposing through text mining

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Computational repositioning and preclinical validation of pentamidine for renal cell cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Drug repositioning by applying 'expression profiles' generated by integrating chemical structure similarity and gene semantic similarity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Computational drug repositioning through heterogeneous network clustering

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Pathway-based drug repositioning using causal inference

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

The year's new drugs & biologics, 2013: Part I.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

MicroRNAs and anticancer drugs.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Biomarker-guided repurposing of chemotherapeutic drugs for cancer therapy: a novel strategy in drug development.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Network based elucidation of drug response: from modulators to targets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Exploring the pharmacogenomics knowledge base (PharmGKB) for repositioning breast cancer drugs by leveraging Web ontology language (OWL) and cheminformatics approaches

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Drug repositioning for orphan genetic diseases through Conserved Anticoexpressed Gene Clusters (CAGCs)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Drug repositioning for treatment of movement disorders: from serendipity to rational discovery strategies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

DNorm: disease name normalization with pairwise learning to rank

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Evaluating cell lines as tumour models by comparison of genomic profiles

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Drug repositioning: a machine-learning approach through data integration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Repositioning metformin for cancer prevention and treatment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Drug repurposing for gastrointestinal stromal tumor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Pharmaco-miR: linking microRNAs and drug effects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

SM2miR: a database of the experimentally validated small molecules' effects on microRNA expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

The risk of primary and contralateral breast cancer after ovarian cancer in BRCA1/BRCA2 mutation carriers: Implications for counseling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Transcriptional data: a new gateway to drug repositioning?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Systematic identification of pharmacogenomics information from clinical trials

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Drug repositioning for personalized medicine.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Identification of links between small molecules and miRNAs in human cancers based on transcriptional responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Improved survival for BRCA2-associated serous ovarian cancer compared with both BRCA-negative and BRCA1-associated serous ovarian cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

A novel method of transcriptional response analysis to facilitate drug repositioning for cancer therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Computational repositioning of the anticonvulsant topiramate for inflammatory bowel disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Literature mining, ontologies and information visualization for drug repurposing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Exploiting drug-disease relationships for computational drug repositioning

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Database identifies FDA-approved drugs with potential to be repurposed for treatment of orphan diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Discovery of drug mode of action and drug repositioning from transcriptional responses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Repositioning of an existing drug for the neglected tropical disease Onchocerciasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Molecular networks as sensors and drivers of common human diseases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Short-term safety and efficacy of intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Systematic prediction of drug combinations based on clinical side-effects

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

BioCreative-IV virtual issue

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Anti-infectious drug repurposing using an integrated chemical genomics and structural systems biology approach.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Trifluoperazine, an antipsychotic agent, inhibits cancer stem cell growth and overcomes drug resistance of lung cancer.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

PROMISCUOUS: a database for network-based drug-repositioning

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

Genomics-enabled drug repositioning and repurposing: insights from an IOM Roundtable activity.

3 June 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIB%2FBBV020

IDMap: facilitating the detection of potential leads with therapeutic targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIB%2FBBV020

Identification of small molecules enhancing autophagic function from drug network analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIB%2FBBV020

Use of genome-wide association studies for drug repositioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIB%2FBBV020

Mining small-molecule screens to repurpose drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIB%2FBBV020

e-Drug3D: 3D structure collections dedicated to drug repurposing and fragment-based drug design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIB%2FBBV020

A hadoop-based method to predict potential effective drug combination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIB%2FBBV020

Meta-analysis of variables affecting mouse protection efficacy of whole organism Brucella vaccines and vaccine candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIB%2FBBV020

Stereoselective virtual screening of the ZINC database using atom pair 3D-fingerprints

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIB%2FBBV020

Experimental confirmation of new drug-target interactions predicted by Drug Profile Matching.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIB%2FBBV020

Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIB%2FBBV020

Infectious diseases. Debate erupts on 'repurposed' drugs for Ebola

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBIB%2FBBV020

Linking PharmGKB to phenotype studies and animal models of disease for drug repurposing.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4719067

The cost of new drug discovery and development

27 November 2018

1 reference

12 December 2020

Prospects for productivity

1 reference

12 December 2020

Drug-disease association and drug-repositioning predictions in complex diseases using causal inference-probabilistic matrix factorization

1 reference

12 December 2020

DCDB: drug combination database

1 reference

12 December 2020

Disease genetics: phenome-wide association studies go large

1 reference

12 December 2020

Old drugs, new tricks

1 reference

12 December 2020

Identifiers

DOI

10.1093/BIB/BBV020

1 reference

DBLP publication ID

journals/bib/LiZCBSL16

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

1 reference

PubMed publication ID

25832646

1 reference