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How old is my gene?
scientific article (publication date: November 2013)
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scholarly article
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title
How old is my gene?
(English)
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author
John Anthony Capra
series ordinal
1
object named as
John A Capra
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Katherine Pollard
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4
object named as
Katherine S Pollard
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Dannie Durand
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3
object named as
Dannie Durand
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author name string
Maureen Stolzer
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2
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language of work or name
English
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publication date
November 2013
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published in
Trends in Genetics
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volume
29
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issue
11
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page(s)
659-68
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cites work
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The universal distribution of evolutionary rates of genes and distinct characteristics of eukaryotic genes of different apparent ages
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17 March 2017
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17 March 2017
A phylostratigraphy approach to uncover the genomic history of major adaptations in metazoan lineages
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17 March 2017
The HHpred interactive server for protein homology detection and structure prediction
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17 March 2017
Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions
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17 March 2017
Ancient DNA
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PubMed Central
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17 March 2017
OrthoMCL: Identification of Ortholog Groups for Eukaryotic Genomes
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17 March 2017
Role of duplicate genes in genetic robustness against null mutations
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17 March 2017
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
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17 March 2017
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17 March 2017
Basic local alignment search tool
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PubMed Central
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17 March 2017
On homology searches by protein Blast and the characterization of the age of genes
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PubMed Central
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23 March 2017
An Ancient Evolutionary Origin of Genes Associated with Human Genetic Diseases
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6 April 2017
Accelerated Profile HMM Searches
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Bayesian estimation of species divergence times under a molecular clock using multiple fossil calibrations with soft bounds
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7 April 2017
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7 April 2017
CAFE: a computational tool for the study of gene family evolution
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7 April 2017
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7 April 2017
Automatic clustering of orthologs and in-paralogs from pairwise species comparisons
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7 April 2017
Resurrecting an ancient enzyme to address gene duplication
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3 June 2018
New functional families (FunFams) in CATH to improve the mapping of conserved functional sites to 3D structures
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Systematic underestimation of the age of selected alleles
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Inferring duplications, losses, transfers and incomplete lineage sorting with nonbinary species trees.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
ProteinHistorian: tools for the comparative analysis of eukaryote protein origin
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Unified modeling of gene duplication, loss, and coalescence using a locus tree
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Models, algorithms and programs for phylogeny reconciliation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Evaluating ortholog prediction algorithms in a yeast model clade
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
MAGUKs, synaptic development, and synaptic plasticity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
The accumulation of gene regulation through time
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Maximum likelihood models and algorithms for gene tree evolution with duplications and losses.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Novel genes exhibit distinct patterns of function acquisition and network integration
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
The interplay between evolution, regulation and tissue specificity in the Human Hereditary Diseasome.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Broker genes in human disease
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Young proteins experience more variable selection pressures than old proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Origins, evolution, and phenotypic impact of new genes.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Count: evolutionary analysis of phylogenetic profiles with parsimony and likelihood
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Evolution of the MAGUK protein gene family in premetazoan lineages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Similarly strong purifying selection acts on human disease genes of all evolutionary ages
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
retrieved
3 June 2018
All human-specific gene losses are present in the genome as pseudogenes
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Phylogenetic and functional assessment of orthologs inference projects and methods
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
retrieved
3 June 2018
Age-dependent evolution of the yeast protein interaction network suggests a limited role of gene duplication and divergence
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Reconciliation with non-binary species trees.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
retrieved
3 June 2018
Mouse duplicate genes are as essential as singletons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
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3 June 2018
Diagnosing duplications--can it be done?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
retrieved
3 June 2018
How old is your fold?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
retrieved
3 June 2018
Evolution of the yeast protein interaction network
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
retrieved
3 June 2018
An orphaned mammalian beta-globin gene of ancient evolutionary origin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
retrieved
3 June 2018
Inferring ancient divergences requires genes with strong phylogenetic signals.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
retrieved
27 November 2018
Younger genes are less likely to be essential than older genes, and duplicates are less likely to be essential than singletons of the same age.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
retrieved
27 November 2018
Historical constraints on vertebrate genome evolution.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
retrieved
27 November 2018
The complex relationship of gene duplication and essentiality.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
retrieved
27 November 2018
Predicting the proportion of essential genes in mouse duplicates based on biased mouse knockout genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
retrieved
27 November 2018
The "inverse relationship between evolutionary rate and age of mammalian genes" is an artifact of increased genetic distance with rate of evolution and time of divergence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3812327
retrieved
27 November 2018
Accelerated Evolutionary Rate May Be Responsible for the Emergence of Lineage-Specific Genes in Ascomycota
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23915718
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Inverse relationship between evolutionary rate and age of mammalian genes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23915718
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.TIG.2013.07.001
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1070025
OpenCitations bibliographic resource ID
1070025
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1070025
PMCID
3812327
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1070025
PubMed ID
23915718
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1070025
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