(Q29568312)

English

Swimming exercise training-induced left ventricular hypertrophy involves microRNAs and synergistic regulation of the PI3K/AKT/mTOR signaling pathway

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

25 April 2017

Swimming exercise training-induced left ventricular hypertrophy involves microRNAs and synergistic regulation of the PI3K/AKT/mTOR signaling pathway (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 April 2017

1 reference

based on heuristic

inferred from title

left ventricular hypertrophy

1 reference

based on heuristic

inferred from title

author name string

Zhichao Ma

1

1 reference

Europe PubMed Central

PubMed publication ID

25 April 2017

Jie Qi

2

1 reference

Europe PubMed Central

PubMed publication ID

25 April 2017

Shuai Meng

3

1 reference

Europe PubMed Central

PubMed publication ID

25 April 2017

Baoju Wen

4

1 reference

Europe PubMed Central

PubMed publication ID

25 April 2017

Jun Zhang

5

1 reference

Europe PubMed Central

PubMed publication ID

25 April 2017

publication date

28 June 2013

1 reference

Europe PubMed Central

PubMed publication ID

25 April 2017

European Journal of Applied Physiology

1 reference

Europe PubMed Central

PubMed publication ID

25 April 2017

113

1 reference

Europe PubMed Central

PubMed publication ID

25 April 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

25 April 2017

2473-2486

1 reference

Europe PubMed Central

PubMed publication ID

25 April 2017

The TSC1-TSC2 complex: a molecular switchboard controlling cell growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of fasting and refeeding on expression of atrogin-1 and Akt/FOXO signaling pathway in skeletal muscle of chicks.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNAs in vertebrate development

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences between pathological and physiological cardiac hypertrophy: novel therapeutic strategies to treat heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapamycin attenuates load-induced cardiac hypertrophy in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Domain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MiR-124 suppresses cell proliferation in hepatocellular carcinoma by targeting PIK3CA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C/EBPβ controls exercise-induced cardiac growth and protects against pathological cardiac remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toward microRNA-based therapeutics for heart disease: the sense in antisense

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphoinositide-3 kinase signaling in cardiac hypertrophy and heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNAs 29 are involved in the improvement of ventricular compliance promoted by aerobic exercise training in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Organization and regulation of mitogen-activated protein kinase signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Focal adhesion kinase -- the basis of local hypertrophic signaling domains

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A human protein kinase Bgamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aerobic exercise training-induced left ventricular hypertrophy involves regulatory MicroRNAs, decreased angiotensin-converting enzyme-angiotensin ii, and synergistic regulation of angiotensin-converting enzyme 2-angiotensin (1-7).

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Convergent signal transduction pathways controlling cardiomyocyte survival and function: the role of PI 3-kinase and Akt.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two new miR-16 targets: caprin-1 and HMGA1, proteins implicated in cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

"Stress-responsive" mitogen-activated protein kinases (c-Jun N-terminal kinases and p38 mitogen-activated protein kinases) in the myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replacement treatment with microRNA-143 and -145 induces synergistic inhibition of the growth of human bladder cancer cells by regulating PI3K/Akt and MAPK signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Swimming training in rats increases cardiac MicroRNA-126 expression and angiogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the cellular functions of PTEN using catalytic domain and C-terminal mutations: differential effects of C-terminal deletion on signalling pathways downstream of phosphoinositide 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PTEN function: how normal cells control it and tumour cells lose it

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mTOR: from growth signal integration to cancer, diabetes and ageing

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNA in prostate, bladder, and kidney cancer: a systematic review.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of PTEN selectively desensitizes upstream IGF1 and insulin signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expanding mTOR signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological functions of Pten in mouse tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comprehensive expression profiling of microRNAs in laryngeal squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphoinositide 3-kinase(p110α) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor I receptor signaling is required for exercise-induced cardiac hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscle-specific Pten deletion protects against insulin resistance and diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TOR signaling in growth and metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNA-144 promotes cell proliferation, migration and invasion in nasopharyngeal carcinoma through repression of PTEN.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PTEN: a tumour suppressor that functions as a phospholipid phosphatase

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of cardiac hypertrophy by intracellular signalling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defining the role of mTOR in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative regulation of miR-145 by C/EBP-β through the Akt pathway in cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of exercise and phosphoinositide 3-kinase(p110alpha) signaling in dilated and hypertrophic cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt1 is required for physiological cardiac growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt2 deficiency promotes cardiac induction of Rab4a and myocardial β-adrenergic hypersensitivity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphoinositide 3-kinases: a conserved family of signal transducers

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The roles of microRNA in cancer and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Swimming training increases cardiac vagal activity and induces cardiac hypertrophy in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns of microRNA expression characterize stages of human B-cell differentiation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TOR, a central controller of cell growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanistic or mammalian target of rapamycin (mTOR) may determine robustness in young male mice at the cost of accelerated aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The fuzzy logic of physiological cardiac hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plexin-B1 is a target of miR-214 in cervical cancer and promotes the growth and invasion of HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance after a 72-h fast is associated with impaired AS160 phosphorylation and accumulation of lipid and glycogen in human skeletal muscle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Akt in cardiac growth and metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased Akt kinase activity and insulin resistance in C57BL/KsJ-Leprdb/db mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The phosphoinositide 3-kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac restricted overexpression of kinase-dead mammalian target of rapamycin (mTOR) mutant impairs the mTOR-mediated signaling and cardiac function

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shp2 negatively regulates growth in cardiomyocytes by controlling focal adhesion kinase/Src and mTOR pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Attenuation of microRNA-22 derepressed PTEN to effectively protect rat cardiomyocytes from hypertrophy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of extracellular signal-regulated kinases 1/2 in cardiac hypertrophy and cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MiRNA-21 reverses high glucose and high insulin induced insulin resistance in 3T3-L1 adipocytes through targeting phosphatase and tensin homologue

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt/protein kinase B promotes organ growth in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian target of rapamycin is a critical regulator of cardiac hypertrophy in spontaneously hypertensive rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local renin-angiotensin system regulates left ventricular hypertrophy induced by swimming training independent of circulating renin: a pharmacological study

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/23812090

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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