(Q30386219)

English

Induction of Macrophage Function in Human THP-1 Cells Is Associated with Rewiring of MAPK Signaling and Activation of MAP3K7 (TAK1) Protein Kinase

scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Induction of Macrophage Function in Human THP-1 Cells Is Associated with Rewiring of MAPK Signaling and Activation of MAP3K7 (TAK1) Protein Kinase (English)

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

author name string

Erik Richter

1

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Katharina Ventz

2

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Manuela Harms

3

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Jörg Mostertz

4

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Falko Hochgräfe

5

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

publication date

30 March 2016

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Frontiers in Cell and Developmental Biology

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

4

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

21

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

TAK1 inhibition-induced RIP1-dependent apoptosis in murine macrophages relies on constitutive TNF-α signaling and ROS production.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Evaluation of Kinase Activity Profiling Using Chemical Proteomics

1 reference

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20 June 2018

Differential phosphorylation of DNA-PKcs regulates the interplay between end-processing and end-ligation during nonhomologous end-joining

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

The lysosome rupture-activated TAK1-JNK pathway regulates NLRP3 inflammasome activation

1 reference

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20 June 2018

Integrity of the actin cytoskeleton of host macrophages is essential for Leishmania donovani infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Activated macrophage survival is coordinated by TAK1 binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

miR-16 and miR-26a target checkpoint kinases Wee1 and Chk1 in response to p53 activation by genotoxic stress

1 reference

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20 June 2018

Protein synthesis rate is the predominant regulator of protein expression during differentiation

1 reference

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20 June 2018

Characterization of the novel broad-spectrum kinase inhibitor CTx-0294885 as an affinity reagent for mass spectrometry-based kinome profiling.

1 reference

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20 June 2018

Deletion of TAK1 in the myeloid lineage results in the spontaneous development of myelomonocytic leukemia in mice

1 reference

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20 June 2018

TAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Epithelial transforming growth factor β-activated kinase 1 (TAK1) is activated through two independent mechanisms and regulates reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Manipulation of kinase signaling by bacterial pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Proteomic biosignatures for monocyte-macrophage differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

p53 downregulates Down syndrome-associated DYRK1A through miR-1246.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Calcium/calmodulin-dependent protein kinase (CaMK) Ialpha mediates the macrophage inflammatory response to sepsis

1 reference

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20 June 2018

Andromeda: a peptide search engine integrated into the MaxQuant environment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Cyclin-dependent kinase 9-cyclin K functions in the replication stress response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Protein-tyrosine phosphatase SHP2 contributes to GDNF neurotrophic activity through direct binding to phospho-Tyr687 in the RET receptor tyrosine kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Phosphorylation of Ser 21 in Fyn regulates its kinase activity, focal adhesion targeting, and is required for cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Unravelling mononuclear phagocyte heterogeneity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Repair of global regulators in Staphylococcus aureus 8325 and comparative analysis with other clinical isolates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Development of monocytes, macrophages, and dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

The kinase TNIK is an essential activator of Wnt target genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Alterations in cellular proteome and secretome upon differentiation from monocyte to macrophage by treatment with phorbol myristate acetate: insights into biological processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Large-scale proteomics analysis of the human kinome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Blood monocytes: development, heterogeneity, and relationship with dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

TAK1 regulates reactive oxygen species and cell death in keratinocytes, which is essential for skin integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

TAK1 is required for the survival of hematopoietic cells and hepatocytes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

TAM receptors are pleiotropic inhibitors of the innate immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Molecular regulation of cytoskeletal rearrangements during T cell signalling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Phosphorylation of the CARMA1 linker controls NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Transcriptional repression of protein kinase Calpha via Sp1 by wild type p53 is involved in inhibition of multidrug resistance 1 P-glycoprotein phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

p53-dependent inhibition of FKHRL1 in response to DNA damage through protein kinase SGK1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Chemotaxis: signalling the way forward

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

A calmodulin-regulated protein kinase linked to neuron survival is a substrate for the calmodulin-regulated death-associated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

DAVID: Database for Annotation, Visualization, and Integrated Discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Properties of 13C-Substituted Arginine in Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

The protein kinase complement of the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

The extracellular toll-like receptor 2 domain directly binds peptidoglycan derived from Staphylococcus aureus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

A role for cofilin and LIM kinase in Listeria-induced phagocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Phagocytosis and clearance of apoptotic cells is mediated by MER.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Phagocytosis and the actin cytoskeleton.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

The polarization defect of Wiskott-Aldrich syndrome macrophages is linked to dislocalization of the Arp2/3 complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

TNIK, a novel member of the germinal center kinase family that activates the c-Jun N-terminal kinase pathway and regulates the cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Targeted disruption of the MKK4 gene causes embryonic death, inhibition of c-Jun NH2-terminal kinase activation, and defects in AP-1 transcriptional activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Differences in the state of differentiation of THP-1 cells induced by phorbol ester and 1,25-dihydroxyvitamin D3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Establishment and characterization of a human acute monocytic leukemia cell line (THP-1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

The structure and function of monocytes and macrophages

1 reference

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20 June 2018

The human leukemia cell line, THP-1: a multifacetted model for the study of monocyte-macrophage differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase)

1 reference

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20 June 2018

Cyclin a is required for the onset of DNA replication in mammalian fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4811913

20 June 2018

Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15

1 reference

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20 June 2018

Xenopus MAP kinase activator: identification and function as a key intermediate in the phosphorylation cascade

1 reference

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20 June 2018

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle

1 reference

https://api.crossref.org/works/10.3389%2FFCELL.2016.00021

21 January 2018

TAK1 inhibition in the DFG-out conformation

1 reference

https://api.crossref.org/works/10.3389%2FFCELL.2016.00021

21 January 2018

Mycobacterium tuberculosis phagosomes exhibit altered calmodulin-dependent signal transduction: contribution to inhibition of phagosome-lysosome fusion and intracellular survival in human macrophages.

1 reference

https://api.crossref.org/works/10.3389%2FFCELL.2016.00021

21 January 2018

Essential function for the kinase TAK1 in innate and adaptive immune responses.

1 reference

https://api.crossref.org/works/10.3389%2FFCELL.2016.00021

21 January 2018

PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1.

1 reference

https://api.crossref.org/works/10.3389%2FFCELL.2016.00021

21 January 2018

The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.

1 reference

https://api.crossref.org/works/10.3389%2FFCELL.2016.00021

21 January 2018

RSK and MSK in MAP kinase signalling

1 reference

https://api.crossref.org/works/10.3389%2FFCELL.2016.00021

21 January 2018

Differences in the effects of phorbol esters and diacylglycerols on protein kinase C

1 reference

https://pubmed.ncbi.nlm.nih.gov/27066479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LIM kinase 1 modulates opsonized zymosan-triggered activation of macrophage-like U937 cells. Possible involvement of phosphorylation of cofilin and reorganization of actin cytoskeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/27066479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent mutations in the p53 gene in human myeloid leukemia cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/27066479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of p53 expression in human myeloid leukemias is not due to mutations in transcriptional regulatory regions of the gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/27066479

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FCELL.2016.00021

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

release_xczegruve5ae7lofibhhqq3iua

1 reference

https://api.fatcat.wiki/v0/release/xczegruve5ae7lofibhhqq3iua

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

ResearchGate publication ID

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