(Q30408061)

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Continuous kynurenine administration during the prenatal period, but not during adolescence, causes learning and memory deficits in adult rats

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scholarly article

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Europe PubMed Central

PMC publication ID

30 September 2017

Continuous kynurenine administration during the prenatal period, but not during adolescence, causes learning and memory deficits in adult rats (English)

1 reference

Europe PubMed Central

PMC publication ID

30 September 2017

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3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24590052%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Ana Pocivavsek

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24590052%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Marian A R Thomas

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24590052%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

John P Bruno

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24590052%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Robert Schwarcz

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24590052%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

publication date

4 March 2014

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Europe PubMed Central

PMC publication ID

30 September 2017

Psychopharmacology

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24590052%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

231

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8 June 2020

14

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24590052%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

2799-2809

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24590052%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Targeting kynurenine aminotransferase II in psychiatric diseases: promising effects of an orally active enzyme inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

The effect of transient increases in kynurenic acid and quinolinic acid levels early in life on behavior in adulthood: Implications for schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Developmental expression of N-methyl-D-aspartate (NMDA) receptor subunits in human white and gray matter: potential mechanism of increased vulnerability in the immature brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Prenatal poly(i:C) exposure and other developmental immune activation models in rodent systems.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Early developmental elevations of brain kynurenic acid impair cognitive flexibility in adults: reversal with galantamine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Kynurenic acid as an antagonist of α7 nicotinic acetylcholine receptors in the brain: facts and challenges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

An expanding range of targets for kynurenine metabolites of tryptophan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Kynurenines in the mammalian brain: when physiology meets pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Glutamatergic synapse formation is promoted by α7-containing nicotinic acetylcholine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Pre- and postnatal exposure to kynurenine causes cognitive deficits in adulthood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Kynurenic acid: a metabolite with multiple actions and multiple targets in brain and periphery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Administration of kynurenine during adolescence, but not during adulthood, impairs social behavior in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Glutamate and nicotinic receptor interactions in working memory: importance for the cognitive impairment of schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Fluctuations in endogenous kynurenic acid control hippocampal glutamate and memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Downregulated kynurenine 3-monooxygenase gene expression and enzyme activity in schizophrenia and genetic association with schizophrenia endophenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Exposure to kynurenic acid during adolescence produces memory deficits in adulthood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Impaired kynurenine pathway metabolism in the prefrontal cortex of individuals with schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Psychological Stress-Induced, IDO1-Dependent Tryptophan Catabolism: Implications on Immunosuppression in Mice and Humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Early life programming and neurodevelopmental disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Cortical kynurenine pathway metabolism: a novel target for cognitive enhancement in Schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Prenatal infection and schizophrenia: a review of epidemiologic and translational studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

CSF concentrations of brain tryptophan and kynurenines during immune stimulation with IFN-alpha: relationship to CNS immune responses and depression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Epidemiology-driven neurodevelopmental animal models of schizophrenia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

A unifying hypothesis of schizophrenia: abnormal immune system development may help explain roles of prenatal hazards, post-pubertal onset, stress, genes, climate, infections, and brain dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Gestational methylazoxymethanol acetate administration: a developmental disruption model of schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

The astrocyte-derived alpha7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Neonatal infection with neurotropic influenza A virus induces the kynurenine pathway in early life and disrupts sensorimotor gating in adult Tap1-/- mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

The dynamic effects of nicotine on the developing brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

The effects of prenatal stress on learning in adult offspring is dependent on the timing of the stressor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

The concept of progressive brain change in schizophrenia: implications for understanding schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Regulation of spine morphology and spine density by NMDA receptor signaling in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Astrocytic localization of kynurenine aminotransferase II in the rat brain visualized by immunocytochemistry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Elevations of endogenous kynurenic acid produce spatial working memory deficits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Brain volume in first-episode schizophrenia: systematic review and meta-analysis of magnetic resonance imaging studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Association study between kynurenine 3-monooxygenase gene and schizophrenia in the Japanese population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Behavioural pharmacology: 40+ years of progress, with a focus on glutamate receptors and cognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Critical period plasticity in local cortical circuits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Increased cortical kynurenate content in schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Interferon-gamma-induced tryptophan degradation: neuropsychiatric and immunological consequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Longitudinal study of brain morphology in first episode schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Synthesis and biochemical evaluation of N-(4-phenylthiazol-2-yl)benzenesulfonamides as high-affinity inhibitors of kynurenine 3-hydroxylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

GABAA, NMDA and AMPA receptors: a developmentally regulated 'ménage à trois'.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Cellular and synaptic localization of NMDA and non-NMDA receptor subunits in neocortex: organizational features related to cortical circuitry, function and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Developments of a water-maze procedure for studying spatial learning in the rat

1 reference

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20 June 2018

Implications of normal brain development for the pathogenesis of schizophrenia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Is schizophrenia a neurodevelopmental disorder?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Chronic effects of γ-interferon on quinolinic acid and indoleamine-2,3-dioxygenase in brain of C57BL6 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Developmental changes in brain kynurenic acid concentrations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4074218

20 June 2018

Presynaptic kynurenate-sensitive receptors inhibit glutamate release

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

Differences in distribution of ages of onset in males and females with schizophrenia.

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

L-kynurenine treatment alters contextual fear conditioning and context discrimination but not cue-specific fear conditioning.

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

Endogenous kynurenic acid disrupts prepulse inhibition

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

The alpha7 nicotinic receptors in human fetal brain and spinal cord

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

Prenatal inhibition of the tryptophan-kynurenine pathway alters synaptic plasticity and protein expression in the rat hippocampus

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

Changes in synaptic transmission and protein expression in the brains of adult offspring after prenatal inhibition of the kynurenine pathway

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

Impaired recruitment of the hippocampus during conscious recollection in schizophrenia

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

Prenatal exposure to a repeated variable stress paradigm elicits behavioral and neuroendocrinological changes in the adult offspring: potential relevance to schizophrenia.

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

Upregulation of the initiating step of the kynurenine pathway in postmortem anterior cingulate cortex from individuals with schizophrenia and bipolar disorder

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

Long-lasting effects of inescapable-predator stress on brain tryptophan metabolism and the behavior of juvenile mice.

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

Elevated levels of kynurenic acid in the cerebrospinal fluid of male patients with schizophrenia

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

α7-Nicotinic acetylcholine receptors: an old actor for new different roles

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

Micromolar Brain Levels of Kynurenic Acid are Associated with a Disruption of Auditory Sensory Gating in the Rat

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

Prenatal exposure to maternal stress and subsequent schizophrenia. The May 1940 invasion of The Netherlands

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

Kynurenine 3-monooxygenase (KMO) polymorphisms in schizophrenia: An association study

1 reference

https://api.crossref.org/works/10.1007%2FS00213-014-3452-2

21 January 2018

Perinatal kynurenine pathway metabolism in the normal and asphyctic rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/24590052

12 December 2020

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inferred from PubMed ID database lookup

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10.1007/S00213-014-3452-2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24590052%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

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0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24590052%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24590052%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

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