(Q31032576)

28 June 2017

title

Integrative methods for analyzing big data in precision medicine (English)

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28 June 2017

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3

Nataša Pržulj

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28 June 2017

author name string

Vladimir Gligorijević

series ordinal

1

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28 June 2017

Noël Malod-Dognin

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2

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28 June 2017

publication date

17 December 2015

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28 June 2017

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28 June 2017

volume

16

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28 June 2017

issue

5

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28 June 2017

page(s)

741-758

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Predictive, personalized, preventive, participatory (P4) cancer medicine.

28 June 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Survival of nationally shared, HLA-matched kidney transplants from cadaveric donors. The UNOS Scientific Renal Transplant Registry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Finishing the euchromatic sequence of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Challenges in Biomarker Discovery: Combining Expert Insights with Statistical Analysis of Complex Omics Data.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Omics and integrated omics for the promotion of food and nutrition science

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Quantitative image analysis of cellular heterogeneity in breast tumors complements genomic profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Radiomics: the process and the challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Radiomics: extracting more information from medical images using advanced feature analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Whole-brain functional imaging at cellular resolution using light-sheet microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The $1,000 genome, the $100,000 analysis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The National Institutes of Health's Big Data to Knowledge (BD2K) initiative: capitalizing on biomedical big data

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Defining a comprehensive verotype using electronic health records for personalized medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Heterogeneity of Parkinson's disease in the early clinical stages using a data driven approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The US Food and Drug Administration perspective on cancer biomarker development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The microeconomics of personalized medicine: today's challenge and tomorrow's promise

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Drug repositioning: identifying and developing new uses for existing drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The complete genome of an individual by massively parallel DNA sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Targeted capture and massively parallel sequencing of 12 human exomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Genetic diagnosis by whole exome capture and massively parallel DNA sequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Single-cell sequencing-based technologies will revolutionize whole-organism science

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Genetics. Genome mosaicism--one human, multiple genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Charting a dynamic DNA methylation landscape of the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

21 January 2018

Mapping human epigenomes

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Cancer epigenetics: from mechanism to therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Epigenetic reprogramming in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Advancing biopharmaceutical process science through transcriptome analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Quantifying the relationship between co-expression, co-regulation and gene function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Use of a cDNA microarray to analyse gene expression patterns in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

A microRNA expression signature of human solid tumors defines cancer gene targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Gene expression profiling predicts clinical outcome of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Modification-specific proteomics: characterization of post-translational modifications by mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Mass spectrometry-based proteomics turns quantitative

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

A novel genetic system to detect protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Conserved pathways within bacteria and yeast as revealed by global protein network alignment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Topological network alignment uncovers biological function and phylogeny

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Systematic identification of functional orthologs based on protein network comparison

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

A genetic approach to Mammalian glycan function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Recognition of bacterial glycosphingolipids by natural killer T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Siglecs: sialic-acid-binding immunoglobulin-like lectins in cell-cell interactions and signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Roles of heparan-sulphate glycosaminoglycans in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Fluxomics - connecting ‘omics analysis and phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Five years of GWAS discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

An integrated map of genetic variation from 1,092 human genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Accurate and comprehensive sequencing of personal genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Non-invasive prenatal measurement of the fetal genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Exhaustive benchmarking of the yeast two-hybrid system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Gene: a gene-centered information resource at NCBI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The UniProt-GO Annotation database in 2011.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The ENCODE (ENCyclopedia Of DNA Elements) Project

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The NIH Roadmap Epigenomics Mapping Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

4DGenome: a comprehensive database of chromatin interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

MethylomeDB: a database of DNA methylation profiles of the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Expression Atlas update--a database of gene and transcript expression from microarray- and sequencing-based functional genomics experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

COXPRESdb in 2015: coexpression database for animal species by DNA-microarray and RNAseq-based expression data with multiple quality assessment systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

GeneFriends: a human RNA-seq-based gene and transcript co-expression database

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

UniProt: a hub for protein information

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The neXtProt knowledgebase on human proteins: current status

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

21 January 2018

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Proteomics. Tissue-based map of the human proteome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The IntAct molecular interaction database in 2012

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The BioGRID interaction database: 2015 update

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Online predicted human interaction database

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

STRING v10: protein-protein interaction networks, integrated over the tree of life

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

HMDB 3.0--The Human Metabolome Database in 2013

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

KEGG: Kyoto Encyclopedia of Genes and Genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

SMPDB 2.0: big improvements to the Small Molecule Pathway Database

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The Reactome pathway knowledgebase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

SugarBind database (SugarBindDB): a resource of pathogen lectins and corresponding glycan targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

UniCarbKB: building a knowledge platform for glycoproteomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

KEGG as a glycome informatics resource

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The NCBI dbGaP database of genotypes and phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The Cancer Genome Atlas Pan-Cancer analysis project

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

DrugBank 4.0: shedding new light on drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

PubChem: a public information system for analyzing bioactivities of small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

T3DB: a comprehensively annotated database of common toxins and their targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Databases on food phytochemicals and their health-promoting effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The UCLA multimodal connectivity database: a web-based platform for brain connectivity matrix sharing and analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The WU-Minn Human Connectome Project: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Structure, function and diversity of the healthy human microbiome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

21 January 2018

Big data bioinformatics.

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Methods for biological data integration: perspectives and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Learning the parts of objects by non-negative matrix factorization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Comprehensive molecular characterization of human colon and rectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Comprehensive molecular portraits of human breast tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Integrated genomic analyses of ovarian carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

A computational method for clinically relevant cancer stratification and driver mutation module discovery using personal genomics profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Clustering cancer gene expression data: a comparative study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Metagenes and molecular pattern discovery using matrix factorization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

KeyPathwayMiner 4.0: condition-specific pathway analysis by combining multiple omics studies and networks with Cytoscape.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Principles and methods of integrative genomic analyses in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Integrative clustering of multiple genomic data types using a joint latent variable model with application to breast and lung cancer subtype analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Integrative subtype discovery in glioblastoma using iCluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Patient-specific data fusion defines prognostic cancer subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Bayesian joint analysis of heterogeneous genomics data

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

JOINT AND INDIVIDUAL VARIATION EXPLAINED (JIVE) FOR INTEGRATED ANALYSIS OF MULTIPLE DATA TYPES.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Network-based stratification of tumor mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

21 January 2018

Cancer genome landscapes

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Pattern discovery and cancer gene identification in integrated cancer genomic data

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Drug repositioning: a machine-learning approach through data integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Drug repositioning by kernel-based integration of molecular structure, molecular activity, and phenotype data

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

PREDICT: a method for inferring novel drug indications with application to personalized medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Inferring drug-disease associations from integration of chemical, genomic and phenotype data using network propagation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Drug repositioning through incomplete bi-cliques in an integrated drug-target-disease network

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Identification of links between small molecules and miRNAs in human cancers based on transcriptional responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Exploiting drug-disease relationships for computational drug repositioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Predicting new molecular targets for known drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Drug target identification using side-effect similarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Human symptoms-disease network

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Prediction of drug-target interaction networks from the integration of chemical and genomic spaces.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Method for comparing the structures of protein ligand-binding sites and application for predicting protein-drug interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Ligand-protein inverse docking and its potential use in the computer search of protein targets of a small molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

An introduction to ROC analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Associating genes and protein complexes with disease via network propagation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Network-based drug repositioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

MicroRNAs as lung cancer biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

MicroRNAs in cancer: biomarkers, functions and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Long non-coding RNAs: insights into functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Predicting lncRNA-disease associations and constructing lncRNA functional similarity network based on the information of miRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Extracting insights from the shape of complex data using topology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Continuous time Bayesian network classifiers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Integrating 'omic' information: a bridge between genomics and systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Defining genetic interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Integration of molecular network data reconstructs Gene Ontology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Exploring the potential of public proteomics data

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Preparing for Precision Medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

Genomics: The single life

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPMIC.201500396

21 January 2018

Identifiers

DOI

10.1002/PMIC.201500396

1 reference

28 June 2017

1 reference