(Q31034463)

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Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidation

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1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidation (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Peter I Mackenzie

object named as

Peter I Mackenzie

3

0 references

author name string

Verawan Uchaipichat

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Leanne K Winner

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

David J Elliot

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

J Andrew Williams

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

John O Miners

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

1 April 2006

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

British Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

61

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

427-439

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Selectivity of substrate (trifluoperazine) and inhibitor (amitriptyline, androsterone, canrenoic acid, hecogenin, phenylbutazone, quinidine, quinine, and sulfinpyrazone) "probes" for human udp-glucuronosyltransferases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Drug-drug interactions for UDP-glucuronosyltransferase substrates: a pharmacokinetic explanation for typically observed low exposure (AUCi/AUC) ratios

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Database analyses for the prediction of in vivo drug-drug interactions from in vitro data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Predicting human drug glucuronidation parameters: application of in vitro and in silico modeling approaches.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

In vitro-in vivo correlations for drugs eliminated by glucuronidation: investigations with the model substrate zidovudine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Inhibition-based metabolic drug-drug interactions: predictions from in vitro data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Sense and nonsense in the prediction of drug-drug interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Quantitative prediction of in vivo drug-drug interactions from in vitro data based on physiological pharmacokinetics: use of maximum unbound concentration of inhibitor at the inlet to the liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Nonspecific binding of drugs to human liver microsomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Microsomal prediction of in vivo clearance of CYP2C9 substrates in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Extrapolating in vitro data on drug metabolism to in vivo pharmacokinetics: evaluation of the pharmacokinetic interaction between amitriptyline and fluoxetine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Glucuronidation of 3'-azido-3'-deoxythymidine (zidovudine) by human liver microsomes: relevance to clinical pharmacokinetic interactions with atovaquone, fluconazole, methadone, and valproic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Quantitative prediction of in vivo drug clearance and drug interactions from in vitro data on metabolism, together with binding and transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

In vitro approaches to predicting drug interactions in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Clinical pharmacokinetics of fluconazole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Pharmacokinetics and bioavailability of fluconazole in patients with AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Intravascular distribution of zidovudine: role of plasma proteins and whole blood components.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Quaternary N-glucuronides of 10-hydroxylated amitriptyline metabolites in human urine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Drug glucuronidation in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Clinical pharmacokinetics of 3'-azido-3'-deoxythymidine (zidovudine) and catabolites with formation of a toxic catabolite, 3'-amino-3'-deoxythymidine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

21 June 2018

Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02588.X

21 January 2018

Effect of albumin on phenytoin and tolbutamide metabolism in human liver microsomes: an impact more than protein binding

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02588.X

21 January 2018

Pharmacophore and quantitative structure activity relationship modelling of UDP-glucuronosyltransferase 1A1 (UGT1A1) substrates

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02588.X

21 January 2018

Isoform selectivity and kinetics of morphine 3- and 6-glucuronidation by human udp-glucuronosyltransferases: evidence for atypical glucuronidation kinetics by UGT2B7.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02588.X

21 January 2018

Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02588.X

21 January 2018

In vitro analysis of human drug glucuronidation and prediction of in vivo metabolic clearance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02588.X

21 January 2018

The comparative interaction of human and bovine serum albumins with CYP2C9 in human liver microsomes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2006.02588.X

21 January 2018

Effect of fluconazole on zidovudine pharmacokinetics in patients infected with human immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

25 November 2018

Correlation between in-vitro microsomal enzyme activity and whole organ hepatic elimination kinetics: analysis with a dispersion model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885031

25 November 2018

Prediction of pharmacokinetic alterations caused by drug-drug interactions: metabolic interaction in the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/16542204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and bioavailability of zidovudine in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16542204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro metabolic interaction studies: experience of the Food and Drug Administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16542204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma and cerebrospinal fluid pharmacokinetics of 3'-azido-3'-deoxythymidine: a novel pyrimidine analog with potential application for the treatment of patients with AIDS and related diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16542204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preventing drug interactions by online prescription screening in community pharmacies and medical practices

1 reference

https://pubmed.ncbi.nlm.nih.gov/16542204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UDP-glucuronosyltransferase1A1 directly binds to albumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16542204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The disposition and metabolism of [14C]fluconazole in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/16542204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of albumin on the estimation, in vitro, of phenytoin Vmax and Km values: implications for clinical correlation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16542204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of in vivo drug-drug interactions between tolbutamide and various sulfonamides in humans based on in vitro experiments

1 reference

https://pubmed.ncbi.nlm.nih.gov/16542204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic and inhibitor studies of 4-methylumbelliferone and 1-naphthol glucuronidation in human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16542204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereoselective metabolism of fenoldopam and its metabolites in human liver microsomes, cytosol, and slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/16542204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucuronidation in vitro and in vivo. Comparison of intestinal and hepatic conjugation of morphine, naloxone, and buprenorphine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16542204

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2125.2006.02588.X

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

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