(Q31088092)

28 June 2017

title

Amyloid-β metabolism in Niemann-Pick C disease models and patients (English)

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Niemann–Pick disease, type C

28 June 2017

main subject

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15

Henrik Zetterberg

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28 June 2017

14

Kaj Blennow

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28 June 2017

16

Erik Portelius

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28 June 2017

10

Gunnar Brinkmalm

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28 June 2017

1

Niklas Mattsson

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28 June 2017

9

Ulf Andreasson

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28 June 2017

Maria Olsson

2

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28 June 2017

Mikael K Gustavsson

3

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28 June 2017

Marko Kosicek

4

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28 June 2017

Martina Malnar

5

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28 June 2017

Jan-Eric Månsson

6

1 reference

28 June 2017

Maria Blomqvist

7

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28 June 2017

Johan Gobom

8

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28 June 2017

Charles Vite

11

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28 June 2017

Silva Hecimovic

12

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28 June 2017

Caroline Hastings

13

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28 June 2017

publication date

1 September 2012

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28 June 2017

published in

Metabolic Brain Disease

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28 June 2017

volume

27

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28 June 2017

issue

4

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28 June 2017

page(s)

573-585

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Paired helical filament tau (PHFtau) in Niemann-Pick type C disease is similar to PHFtau in Alzheimer's disease

28 June 2017

cites work

1 reference

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Effect of immunotherapy with bapineuzumab on cerebrospinal fluid biomarker levels in patients with mild to moderate Alzheimer disease

21 January 2018

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Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein

21 January 2018

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Macroautophagy is not directly involved in the metabolism of amyloid precursor protein

21 January 2018

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Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo

21 January 2018

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Changes in cholesterol metabolism are associated with PS1 and PS2 gene regulation in SK-N-BE.

21 January 2018

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The cholesterol transport inhibitor U18666a regulates amyloid precursor protein metabolism and trafficking in N2aAPP "Swedish" cells

21 January 2018

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Variation in NPC1, the gene encoding Niemann-Pick C1, a protein involved in intracellular cholesterol transport, is associated with Alzheimer disease and/or aging in the Polish population

21 January 2018

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Amyloid beta as a regulator of lipid homeostasis

21 January 2018

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Evaluation of plasma Abeta(40) and Abeta(42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment

21 January 2018

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21 January 2018

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21 January 2018

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Effects of membrane lipids on the activity and processivity of purified γ-secretase

21 January 2018

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Inhibition of cathepsin B reduces beta-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate beta-secretase of Alzheimer's disease

21 January 2018

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Intracellular accumulation of amyloidogenic fragments of amyloid-beta precursor protein in neurons with Niemann-Pick type C defects is associated with endosomal abnormalities

21 January 2018

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Increased expression of the lysosomal cholesterol transporter NPC1 in Alzheimer's disease

21 January 2018

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Altered levels and distribution of amyloid precursor protein and its processing enzymes in Niemann-Pick type C1-deficient mouse brains

21 January 2018

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Chronic exposure to U18666A is associated with oxidative stress in cultured murine cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9332-8

Cholesterol accumulation in Niemann Pick type C (NPC) model cells causes a shift in APP localization to lipid rafts

21 January 2018

1 reference

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Cholesterol movement in Niemann-Pick type C cells and in cells treated with amphiphiles

21 January 2018

1 reference

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Niemann-Pick type C cells show cholesterol dependent decrease of APP expression at the cell surface and its increased processing through the beta-secretase pathway

21 January 2018

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Gamma-secretase-dependent amyloid-beta is increased in Niemann-Pick type C: a cross-sectional study

21 January 2018

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Miglustat treatment may reduce cerebrospinal fluid levels of the axonal degeneration marker tau in niemann-pick type C.

21 January 2018

1 reference

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BACE1 inhibition induces a specific cerebrospinal fluid β-amyloid pattern that identifies drug effects in the central nervous system

21 January 2018

1 reference

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A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid

21 January 2018

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Neurodegenerative lysosomal disorders: a continuum from development to late age.

21 January 2018

1 reference

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Growth factors and cytokines/chemokines as surrogate biomarkers in cerebrospinal fluid and blood for diagnosing Alzheimer's disease and mild cognitive impairment

21 January 2018

1 reference

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Simultaneous measurement of beta-amyloid(1-42), total tau, and phosphorylated tau (Thr181) in cerebrospinal fluid by the xMAP technology.

21 January 2018

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Miglustat for treatment of Niemann-Pick C disease: a randomised controlled study

21 January 2018

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Recommendations for the diagnosis and management of Niemann-Pick disease type C: an update

21 January 2018

1 reference

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Normalization of cholesterol homeostasis by 2-hydroxypropyl-β-cyclodextrin in neurons and glia from Niemann-Pick C1 (NPC1)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9332-8

Miglustat in patients with Niemann-Pick disease Type C (NP-C): a multicenter observational retrospective cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9332-8

Determination of beta-amyloid peptide signatures in cerebrospinal fluid using immunoprecipitation-mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9332-8

Characterization of amyloid beta peptides in cerebrospinal fluid by an automated immunoprecipitation procedure followed by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9332-8

Acute effect on the Aβ isoform pattern in CSF in response to γ-secretase modulator and inhibitor treatment in dogs

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11011-012-9332-8

Novel aβ isoforms in Alzheimer's disease - their role in diagnosis and treatment

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11011-012-9332-8

A novel pathway for amyloid precursor protein processing

21 January 2018

1 reference

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Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

21 January 2018

1 reference

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Type C Niemann-Pick disease: use of hydrophobic amines to study defective cholesterol transport

21 January 2018

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Cerebrospinal fluid profiles of amyloid β-related biomarkers in Alzheimer's disease

21 January 2018

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Niemann‐Pick type C disease: molecular mechanisms and potential therapeutic approaches

21 January 2018

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21 January 2018

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The regulation of beta-secretase by cholesterol and statins in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9332-8

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9332-8

Mutation analysis of feline Niemann-Pick C1 disease

21 January 2018

1 reference

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Structure-based design of potent and selective cell-permeable inhibitors of human beta-secretase (BACE-1).

21 January 2018

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A meta-analysis of cytokines in Alzheimer's disease

21 January 2018

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Clinical, electrophysiological, and serum biochemical measures of progressive neurological and hepatic dysfunction in feline Niemann-Pick type C disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9332-8

2-hydroxypropyl-beta-cyclodextrin raises hearing threshold in normal cats and in cats with Niemann-Pick type C disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9332-8

Accumulation and aggregation of amyloid beta-protein in late endosomes of Niemann-pick type C cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11011-012-9332-8

Presenilin redistribution associated with aberrant cholesterol transport enhances beta-amyloid production in vivo.

21 January 2018

1 reference

12 December 2020

Longitudinal cerebrospinal fluid biomarkers over four years in mild cognitive impairment

1 reference

12 December 2020

Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones

1 reference

12 December 2020

Interactions of Npc1 and amyloid accumulation/deposition in the APP/PS1 mouse model of Alzheimer's

1 reference

12 December 2020

Amino-truncated amyloid beta-peptide (Abeta5-40/42) produced from caspase-cleaved amyloid precursor protein is deposited in Alzheimer's disease brain.

1 reference

12 December 2020

Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells.

1 reference

12 December 2020

Niemann-Pick type C disease: accelerated neurofibrillary tangle formation and amyloid beta deposition associated with apolipoprotein E epsilon 4 homozygosity

1 reference

12 December 2020

An online nano-LC-ESI-FTICR-MS method for comprehensive characterization of endogenous fragments from amyloid β and amyloid precursor protein in human and cat cerebrospinal fluid

1 reference

12 December 2020

10.1007/S11011-012-9332-8

Identifiers

DOI

1 reference

Dimensions Publication ID

28 June 2017

1027604820

0 references

1 reference