(Q31142265)

29 June 2017

Bis(glutathionyl)spermine and other novel trypanothione analogues in Trypanosoma cruzi (English)

1 reference

29 June 2017

0 references

Sandra L Oza

2

0 references

Alan Fairlamb

object named as

Alan H Fairlamb

series ordinal

4

0 references

Mark R Ariyanayagam

series ordinal

1

object named as

Mark R Ariyanayagam

1 reference

29 June 2017

Angela Mehlert

3

1 reference

PubMed ID

12750367

29 June 2017

language of work or name

English

0 references

publication date

15 May 2003

1 reference

Journal of Biological Chemistry

29 June 2017

1 reference

29 June 2017

278

1 reference

29 June 2017

30

1 reference

29 June 2017

27612-27619

1 reference

Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

29 June 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Roles of the glutathione- and thioredoxin-dependent reduction systems in the Escherichia coli and saccharomyces cerevisiae responses to oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Metabolism and functions of trypanothione in the Kinetoplastida

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Identification and functional characterization of thioredoxin from Trypanosoma brucei brucei.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Cloning, expression and reconstitution of the trypanothione-dependent peroxidase system of Crithidia fasciculata

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Trypanosoma cruzi expresses a plant-like ascorbate-dependent hemoperoxidase localized to the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Trypanothione-dependent synthesis of deoxyribonucleotides by Trypanosoma brucei ribonucleotide reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Disruption of the trypanothione reductase gene of Leishmania decreases its ability to survive oxidative stress in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Down-regulation of Leishmania donovani trypanothione reductase by heterologous expression of a trans-dominant mutant homologue: effect on parasite intracellular survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Purification and characterization of trypanothione reductase from Crithidia fasciculata, a newly discovered member of the family of disulfide-containing flavoprotein reductases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Glutathione and trypanothione in parasitic hydroperoxide metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Purification of glutathionylspermidine and trypanothione synthetases from Crithidia fasciculata

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Trypanothione as a target in the design of antitrypanosomal and antileishmanial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

The biosynthesis of trypanothione and N1-glutathionylspermidine in Crithidia fasciculata.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Identification and biosynthesis of N1,N9-bis(glutathionyl)aminopropylcadaverine (homotrypanothione) in Trypanosoma cruzi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Characterization of Trypanosoma brucei gamma-glutamylcysteine synthetase, an essential enzyme in the biosynthesis of trypanothione (diglutathionylspermidine).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Regulation of a high-affinity diamine transport system in Trypanosoma cruzi epimastigotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Cloning and characterization of the two enzymes responsible for trypanothione biosynthesis in Crithidia fasciculata.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

A single enzyme catalyses formation of Trypanothione from glutathione and spermidine in Trypanosoma cruzi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Glutathionylspermidine metabolism in Escherichia coli. Purification, cloning, overproduction, and characterization of a bifunctional glutathionylspermidine synthetase/amidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Characterization of recombinant glutathionylspermidine synthetase/amidase from Crithidia fasciculata

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Diamine auxotrophy may be a universal feature of Trypanosoma cruzi epimastigotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Levels of polyamines, glutathione and glutathione-spermidine conjugates during growth of the insect trypanosomatid Crithidia fasciculata.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Entamoeba histolytica lacks trypanothione metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Ovothiol and trypanothione as antioxidants in trypanosomatids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Determination of biothiols by bromobimane labeling and high-performance liquid chromatography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Site-directed mutagenesis of the redox-active cysteines of Trypanosoma cruzi trypanothione reductase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Nucleotide sequences provide evidence of genetic exchange among distantly related lineages of Trypanosoma cruzi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Differentiation of PC12 cells induced by N8-acetylspermidine and by N8-acetylspermidine deacetylase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Genetic analysis of spermidine synthase from Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Crystal structure of Trypanosoma cruzi trypanothione reductase in complex with trypanothione, and the structure-based discovery of new natural product inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

In vivo effects of difluoromethylornithine on trypanothione and polyamine levels in bloodstream forms of Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Ornithine Decarboxylase Gene Deletion Mutants ofLeishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Absence of plasma amine oxidase in some frequently used animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

Effect of N8-acetylspermidine deacetylase inhibition on the growth of L1210 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M302750200

21 January 2018

Identifiers

DOI

10.1074/JBC.M302750200

1 reference

29 June 2017

1 reference

PubMed ID

12750367