(Q32062435)

6 July 2017

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title

Regulation of the G1 to S transition by the ubiquitin pathway (English)

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6 July 2017

L M DeSalle

1

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6 July 2017

M Pagano

series ordinal

2

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6 July 2017

language of work or name

English

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publication date

1 February 2001

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6 July 2017

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6 July 2017

volume

490

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6 July 2017

issue

3

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6 July 2017

page(s)

179-189

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Basic Medical Research Award. The ubiquitin system

6 July 2017

cites work

1 reference

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21 January 2018

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The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases

21 January 2018

1 reference

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Proteolysis and the cell cycle: with this RING I do thee destroy

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Proteolysis and the G1-S transition: the SCF connection

21 January 2018

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Universal control mechanism regulating onset of M-phase

21 January 2018

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Driving the cell cycle: M phase kinase, its partners, and substrates

21 January 2018

1 reference

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CDK inhibitors: positive and negative regulators of G1-phase progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

The yeast cell cycle gene CDC34 encodes a ubiquitin-conjugating enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

An inhibitor of p34CDC28 protein kinase activity from Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

21 January 2018

1 reference

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Linkage of replication to start by the Cdk inhibitor Sic1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

The cyclin-dependent kinase inhibitor p40SIC1 imposes the requirement for Cln G1 cyclin function at Start

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

SIC1 is ubiquitinated in vitro by a pathway that requires CDC4, CDC34, and cyclin/CDK activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Combinatorial control in ubiquitin-dependent proteolysis: don't Skp the F-box hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Identification of a family of human F-box proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

A family of mammalian F-box proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

A novel member of the F-box/WD40 gene family, encoding dactylin, is disrupted in the mouse dactylaplasia mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Regulation of the Hedgehog and Wingless signalling pathways by the F-box/WD40-repeat protein Slimb

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

The SCF ubiquitin ligase protein slimb regulates centrosome duplication in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

SCF and Cullin/Ring H2-based ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Ubiquitin-like proteins: new wines in new bottles

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

G1 phase progression: cycling on cue

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Deregulated cyclin E induces chromosome instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

The SCF(HOS/beta-TRCP)-ROC1 E3 ubiquitin ligase utilizes two distinct domains within CUL1 for substrate targeting and ubiquitin ligation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Identification of a set of genes with developmentally down-regulated expression in the mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

A new NEDD8-ligating system for cullin-4A

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Conjugation of the ubiquitin-like protein NEDD8 to cullin-2 is linked to von Hippel-Lindau tumor suppressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Covalent modification of all members of human cullin family proteins by NEDD8

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Saccharomyces cerevisiae cdc15 mutants arrested at a late stage in anaphase are rescued by Xenopus cDNAs encoding N-ras or a protein with beta-transducin repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

The F-box protein family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

IkappaBalpha ubiquitination is catalyzed by an SCF-like complex containing Skp1, cullin-1, and two F-box/WD40-repeat proteins, betaTrCP1 and betaTrCP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

beta-TrCP mediates the signal-induced ubiquitination of IkappaBbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Ubiquitin-mediated processing of NF-kappa B transcriptional activator precursor p105. Reconstitution of a cell-free system and identification of the ubiquitin-carrier protein, E2, and a novel ubiquitin-protein ligase, E3, involved in conjugation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

SCF(beta)(-TrCP) ubiquitin ligase-mediated processing of NF-kappaB p105 requires phosphorylation of its C-terminus by IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

HOS, a human homolog of Slimb, forms an SCF complex with Skp1 and Cullin1 and targets the phosphorylation-dependent degradation of IkappaB and beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Identification and characterization of an IkappaB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Direct Phosphorylation of IB by IKK and IKK: Discrimination Between Free and NF-B-Bound Substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Molecular dissection of the interactions among IkappaBalpha, FWD1, and Skp1 required for ubiquitin-mediated proteolysis of IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Beta-catenin as oncogene: the smoking gun.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Frequent beta-catenin abnormalities in bone and soft-tissue tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

A common human skin tumour is caused by activating mutations in beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Five human genes encoding F-box proteins: chromosome mapping and analysis in human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Cyclin E-CDK2 is a regulator of p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Proteasome-dependent degradation of p27/kip1 in gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Ubiquitin-mediated proteolysis: biological regulation via destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Ubiquitination of the G1 cyclin Cln2p by a Cdc34p-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

There's the rub: a novel ubiquitin-like modification linked to cell cycle regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Association of human SCF(SKP2) subunit p19(SKP1) with interphase centrosomes and mitotic spindle poles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2801%2902121-4

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-5793(01)02121-4

1 reference

6 July 2017

1 reference