(Q33286452)

English

Non-homologous recombination of deoxyribonucleoside kinases from human and Drosophila melanogaster yields human-like enzymes with novel activities

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 July 2017

Non-homologous recombination of deoxyribonucleoside kinases from human and Drosophila melanogaster yields human-like enzymes with novel activities (English)

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Drosophila melanogaster

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object named as

Monica L Gerth

1

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author name string

Stefan Lutz

2

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Europe PubMed Central

PubMed publication ID

25 July 2017

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publication date

22 May 2007

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Europe PubMed Central

PubMed publication ID

25 July 2017

Journal of Molecular Biology

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Europe PubMed Central

PubMed publication ID

25 July 2017

370

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Europe PubMed Central

PubMed publication ID

25 July 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

742-751

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

Mutagenesis of non-conserved active site residues improves the activity and narrows the specificity of human thymidine kinase 2

1 reference

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Structure-guided SCHEMA recombination of distantly related beta-lactamases

1 reference

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Kinetic properties of mutant deoxyguanosine kinase in a case of reversible hepatic mtDNA depletion

1 reference

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Structure-guided recombination creates an artificial family of cytochromes P450.

1 reference

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Gemcitabine resistance due to deoxycytidine kinase deficiency can be reverted by fruitfly deoxynucleoside kinase, DmdNK, in human uterine sarcoma cells

1 reference

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21 June 2018

Evolution of highly active enzymes by homology-independent recombination

1 reference

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A second-generation system for unbiased reading frame selection

1 reference

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21 June 2018

Substrate specificity and phosphorylation of antiviral and anticancer nucleoside analogues by human deoxyribonucleoside kinases and ribonucleoside kinases

1 reference

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Enhanced crossover SCRATCHY: construction and high-throughput screening of a combinatorial library containing multiple non-homologous crossovers.

1 reference

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The creation of ITCHY hybrid protein libraries

1 reference

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SWISS-MODEL: An automated protein homology-modeling server

1 reference

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21 June 2018

Structure of human dCK suggests strategies to improve anticancer and antiviral therapy

1 reference

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Structural Basis for Feedback Inhibition of the Deoxyribonucleoside Salvage Pathway: Studies of the Drosophila Deoxyribonucleoside Kinase

1 reference

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Mosquito has a single multisubstrate deoxyribonucleoside kinase characterized by unique substrate specificity

1 reference

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21 June 2018

Structure and function of cellular deoxyribonucleoside kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986717

21 June 2018

A few amino acid substitutions can convert deoxyribonucleoside kinase specificity from pyrimidines to purines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986717

21 June 2018

Creating multiple-crossover DNA libraries independent of sequence identity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1986717

21 June 2018

Structural basis for substrate specificities of cellular deoxyribonucleoside kinases

1 reference

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21 June 2018

Libraries of hybrid proteins from distantly related sequences

1 reference

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Rapid generation of incremental truncation libraries for protein engineering using alpha-phosphothioate nucleotides.

1 reference

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21 June 2018

Retroviral transduction of cancer cell lines with the gene encoding Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.

1 reference

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21 June 2018

Functional expression of a multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster and its C-terminal deletion mutants

1 reference

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A combinatorial approach to hybrid enzymes independent of DNA homology

1 reference

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Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling

1 reference

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How to measure and predict the molar absorption coefficient of a protein

1 reference

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Identification of important residues within the putative nucleoside binding site of HSV-1 thymidine kinase by random sequence selection: analysis of selected mutants in vitro

1 reference

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A deoxythymidine kinase deficient mutant of Escherichia coli. II. Mapping and transduction studies with phage phi 80.

1 reference

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1 reference

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The role of cytoplasmic deoxycytidine kinase in the mitochondrial effects of the anti-human immunodeficiency virus compound, 2‘,3‘-dideoxycytidine

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Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: illuminating the role of main-chain reorganization

1 reference

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1 reference

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12 December 2020

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10.1016/J.JMB.2007.05.021

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 July 2017

ResearchGate publication ID

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