(Q28620349)

English

Substrate specificity and phosphorylation of antiviral and anticancer nucleoside analogues by human deoxyribonucleoside kinases and ribonucleoside kinases

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scholarly article

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3 February 2017

1 reference

Europe PubMed Central

Substrate specificity and phosphorylation of antiviral and anticancer nucleoside analogues by human deoxyribonucleoside kinases and ribonucleoside kinases (English)

1 reference

3 February 2017

phosphorylation

0 references

3

object named as

Anna Karlsson

1 reference

3 February 2017

author name string

An R. Van Rompay

1

1 reference

3 February 2017

Magnus Johansson

2

1 reference

3 February 2017

publication date

1 November 2003

1 reference

3 February 2017

Pharmacology & Therapeutics

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3 February 2017

100

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3 February 2017

2

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3 February 2017

119–139

1 reference

3 February 2017

The partial purification and properties of uridine kinase from Ehrlich ascites tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity of antiretroviral nucleoside and nucleotide analogues: is mitochondrial toxicity the only mechanism?

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common resistance mechanisms to deoxynucleoside analogues in variants of the human erythroleukaemic line K562.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human Nm23/nucleoside diphosphate kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular signaling pathways affect the function of ribonucleotide reductase mRNA binding proteins: mRNA stabilization, drug resistance, and malignancy (Review).

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Feedback onhibition of uridine kinase by cytidine triphosphate and uridine triphosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and expression of a cDNA encoding uridine kinase from mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical characteristics of gemcitabine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions between deoxyribonucleotide and DNA synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism and action of purine nucleoside analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zidovudine-induced mitochondrial disorder with massive liver steatosis, myopathy, lactic acidosis, and mitochondrial DNA depletion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of human adenosine kinase at 1.5 A resolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of uridine kinase. Evidence for a regulatory site

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA depletion: mutations in thymidine kinase gene with myopathy and SMA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential inhibitory effects of several pyrimidine 2',3'-dideoxynucleoside 5'-triphosphates on the activities of reverse transcriptase and various cellular DNA polymerases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human thymidine kinase gene: molecular cloning and nucleotide sequence of a cDNA expressible in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The herpesvirus encoded dUTPase as a potential chemotherapeutic target

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential incorporation of 1-beta-D-arabinofuranosylcytosine and 9-beta-D-arabinofuranosylguanine into nuclear and mitochondrial DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of enzymic activity by metabolites. I. Uridine-cytidine kinase of Novikoff ascites rat tumor

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophoretically distinct forms of uridine kinase in the rat. Tissue distribution and age-dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deoxycytidine deaminase-resistant stereoisomer is the active form of (+/-)-2',3'-dideoxy-3'-thiacytidine in the inhibition of hepatitis B virus replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

3'-Deoxythymidin-2'-ene permeation of human lymphocyte H9 cells by nonfacilitated diffusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical pharmacology and resistance to 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, a novel analogue of cladribine in human leukemic cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in pyrimidine metabolism in L5178Y leukemia cells resistant to 6-azauridine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pre-steady-state kinetic analysis of substrate binding to human recombinant deoxycytidine kinase: a model for nucleoside kinase action

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human placental adenosine kinase. Kinetic mechanism and inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of uridine triphosphate in the phosphorylation of 1-beta-D-arabinofuranosylcytosine by Ehrlich ascites tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eukaryotic DNA replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis induces efflux of the mitochondrial matrix enzyme deoxyguanosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased uridine kinase (ATP: uridine 5'-phosphotransferase; EC 2.7.1.48) activity in human and rat tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advances in clinical diagnosis and treatment of severe acute respiratory syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of anti-human immunodeficiency virus nucleoside analogs on mitochondrial DNA and its implication for delayed toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria as a target for inducing death of malignant hematopoietic cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human thymidine kinase 1. Regulation in normal and malignant cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of three testis-specific genes (TSA303, TSA806, TSA903) by a differential mRNA display method

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of purine deoxyribonucleoside kinases from human leukemia cells: substrate activation by purine and pyrimidine deoxyribonucleosides

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and expression of human deoxycytidine kinase cDNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uridine - Cytidine Kinase from Foetal and Adult Rat Liver. Purification and Study of Some Properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of dUTPase and uracil-DNA repair in cancer chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of synthesis of ribonucleotide reductase and relationship to DNA replication in various systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyrimidine Biosynthesis during Development of Rat Cerebellum

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-human immunodeficiency virus type 1 activity and in vitro toxicity of 2'-deoxy-3'-thiacytidine (BCH-189), a novel heterocyclic nucleoside analog

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro transcription of DNA containing 2-chloro-2'-deoxyadenosine monophosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A deoxyribonucleotidase in mitochondria: involvement in regulation of dNTP pools and possible link to genetic disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and characterization of the multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deoxyguanosine kinase. Distinct molecular forms in mitochondria and cytosol

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclopentenyl cytosine inhibits cytidine triphosphate synthetase in paediatric acute non-lymphocytic leukaemia: a promising target for chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human thymidine kinase 2: molecular cloning and characterisation of the enzyme activity with antiviral and cytostatic nucleoside substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced cytotoxicity of nucleoside analogs by overexpression of mitochondrial deoxyguanosine kinase in cancer cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytosine arabinoside influx and nucleoside transport sites in acute leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effect of an adenosine kinase inhibitor in septic shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of anticancer nucleoside analogs by human mitochondrial deoxyguanosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential patterns of intracellular metabolism of 2',3'-didehydro-2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine, two potent anti-human immunodeficiency virus compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Submitochondrial localization and characteristics of thymidine kinase molecular forms in parental and kinase-deficient hela cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleoside transporters: molecular biology and implications for therapeutic development

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA structure and polymerase fidelity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the anti-hepatitis B nucleoside analog 1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil (FIAU) by human cytosolic and mitochondrial thymidine kinase and implications for cytotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structures of Toxoplasma gondii adenosine kinase reveal a novel catalytic mechanism and prodrug binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of mutational loss of adenosine kinase and deoxycytidine kinase on deoxyATP accumulation and deoxyadenosine toxicity in cultured CEM human T-lymphoblastoid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initial studies on the cellular pharmacology of 2',3-dideoxycytidine, an inhibitor of HTLV-III infectivity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retroviral transfer of deoxycytidine kinase into tumor cell lines enhances nucleoside toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential induction of apoptosis by fludarabine monophosphate in leukemic B and normal T cells in chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of RNA transcription: a biochemical mechanism of action against chronic lymphocytic leukemia cells by fludarabine

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine kinase inhibitors. 2. Synthesis, enzyme inhibition, and antiseizure activity of diaryltubercidin analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perspectives on the molecular mechanism of inhibition and toxicity of nucleoside analogs that target HIV-1 reverse transcriptase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arabinosylguanine-induced apoptosis of T-lymphoblastic cells: incorporation into DNA is a necessary step

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleotide specificity of human deoxycytidine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA replication fidelity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lethal mutagenesis of HIV with mutagenic nucleoside analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2'-O-Acyl/alkyl-substituted arabinosyl nucleosides as inhibitors of human mitochondrial thymidine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel ribofuranosylnucleoside lead compounds for potent and selective inhibitors of mitochondrial thymidine kinase-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of the cellular pharmacokinetics and toxicity of 2',2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-Chloro-2'-deoxyadenosine, an antileukemic drug, has an early effect on cellular mitochondrial function

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of deoxycytidine kinase and phosphorylation of 2-chlorodeoxyadenosine in human normal and tumour cells and tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The separated enantiomers of 2'-deoxy-3'-thiacytidine (BCH 189) both inhibit human immunodeficiency virus replication in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of retroviral dUTPases in replication and virulence

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purine salvage pathways in myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleoside analogues and nucleobases in cancer treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The intracellular localization of deoxycytidine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian deoxyribonucleoside kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationships among Ara-CTP pools, formation of (Ara-C)DNA, and cytotoxicity of human leukemic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The deoxyguanosine kinase gene is mutated in individuals with depleted hepatocerebral mitochondrial DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and expression of human deoxyguanosine kinase cDNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2',2'-Difluoro-deoxycytidine (gemcitabine) incorporation into RNA and DNA of tumour cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration of the pharmacokinetics of high-dose ara-C by its metabolite, high ara-U in patients with acute leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of mouse mitochondrial thymidine kinase 2 cDNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of nucleosides and nucleoside analogs by mammalian nucleoside monophosphate kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fludarabine: pharmacokinetics, mechanisms of action, and rationales for combination therapies

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: Possible role of nucleoside kinase(s)

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mammalian thymidine kinase 2. Direct photoaffinity labeling with [32P]dTTP of the enzyme from spleen, liver, heart and brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic mechanism and inhibition of human liver thymidine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine kinase from rabbit liver. II. Substrate and inhibitor specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of residues involved in the substrate specificity of human and murine dCK

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance to 1-beta-D-arabinofuranosylcytosine in human T-lymphoblasts mediated by mutations within the deoxycytidine kinase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial genome: structure, transcription, translation and replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial injury. Lessons from the fialuridine trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STUDIES ON 5-HYDROXYURIDINE

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uridine kinase: altered enzyme with decreased affinities for uridine and CTP

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical antitumor activity of 2-chloro-9-(2-deoxy-2-fluoro-beta-D- arabinofuranosyl)adenine (Cl-F-ara-A).

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation and drug resistance mechanisms of mammalian ribonucleotide reductase, and the significance to DNA synthesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-activity studies on mammalian adenosine kinase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial toxicity of antiviral drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Some properties of uridine-cytidine kinase from a human malignant lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of viral and human dUTPase in Epstein-Barr virus-associated diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-nucleoside inhibitors of mitochondrial thymidine kinase (TK-2) differentially inhibit the closely related herpes simplex virus type 1 TK and Drosophila melanogaster multifunctional deoxynucleoside kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complete hematologic and cytogenetic response to 2-amino-9-beta-D-arabinosyl-6-methoxy-9H-guanine in a patient with chronic myelogenous leukemia in T-cell blastic phase: a case report and review of the literature.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and characterization of full-length mouse thymidine kinase 2: the N-terminal sequence directs import of the precursor protein into mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uridine kinase in embryonic rat liver. Modulation of enzyme activity by 5-azacytidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine--a cardioprotective and therapeutic agent

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical pharmacology of (+)- and (-)-2',3'-dideoxy-3'-thiacytidine as anti-hepatitis B virus agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial and submitochondrial localization of human deoxyguanosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine kinase inhibitor GP515 improves experimental colitis in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diverging substrate specificity of pure human thymidine kinases 1 and 2 against antiviral dideoxynucleosides

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of deoxyguanosine toxicity for human T and B lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zidovudine phosphorylation and mitochondrial toxicity in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The treatment of chronic progressive multiple sclerosis with cladribine

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the mechanism of activation of 9-beta-D-arabinofuranosyladenine in human lymphoid cells using mutants deficient in nucleoside kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties of uridine-cytidine kinase derived from L1210 leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deoxyadenosine metabolism and cytotoxicity in cultured mouse T lymphoma cells: a model for immunodeficiency disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Advances in the therapy of chronic lymphocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The intracellular phosphorylation of (-)-2'-deoxy-3'-thiacytidine (3TC) and the incorporation of 3TC 5'-monophosphate into DNA by HIV-1 reverse transcriptase and human DNA polymerase gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties: I. In vitro characterization and acute antinociceptive eff

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple forms of uridine kinase in normal and neoplastic rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and expression of uridine/cytidine kinase cDNA from human fibrosarcoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria as Cell Targets of AZT (Zidovudine)

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization and ordering of acid alpha-glucosidase (GAA) and thymidine kinase (TK1) by fluorescence in situ hybridization

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in kinetic properties of pure recombinant human and mouse deoxycytidine kinase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual mechanisms of 9-beta-D-arabinofuranosylguanine resistance in CEM T-lymphoblast leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology of purine nucleoside analogues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development and optimization of anti-HIV nucleoside analogs and prodrugs: A review of their cellular pharmacology, structure-activity relationships and pharmacokinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of adenosine kinase from Toxoplasma gondii at 1.8 Å resolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human deoxythymidine kinase. I. Purification and general properties of the cytoplasmic and mitochondrial isozymes derived from blast cells of acute myelocytic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance of mammalian tumour cells toward pyrimidine analogues. A review

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deoxycytidine kinase, thymidine kinase and cytidine deaminase and the formation of Ara-CTP in leukemic cells in different phases of the cell cycle

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro biological activity of 9-beta-D-arabinofuranosyl-2-fluoroadenine and the biochemical actions of its triphosphate on DNA polymerases and ribonucleotide reductase from HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FISH localization of the soluble thymidine kinase gene (TK1) to human 17q25, a region of chromosomal loss in sporadic breast tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA depletion and dGK gene mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural basis for substrate specificities of cellular deoxyribonucleoside kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase II placebo-controlled trial of fozivudine tidoxil for HIV infection: pharmacokinetics, tolerability, and efficacy

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effects of 2-thiouracil and 2-thiouracil metabolites on enzymes involved in pyrimidine nucleotide biosynthesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation pathways of 5-fluorouracil in rat organs and in PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assignment of the human deoxycytidine kinase (DCK) gene to chromosome 4 band q13.3-q21.1

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional compartmentation of dCTP pools. Preferential utilization of salvaged deoxycytidine for DNA repair in human lymphoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and properties of human placental adenosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate specificity of mitochondrial 2'-deoxyguanosine kinase. Efficient phosphorylation of 2-chlorodeoxyadenosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive and negative regulation of the human thymidine kinase promoter mediated by CCAAT binding transcription factors NF-Y/CBF, dbpA, and CDP/cut.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine kinase initiates the major route of ribavirin activation in a cultured human cell line

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of deoxycytidine analog monophosphates by UMP-CMP kinase: molecular characterization of the human enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uridine kinase activities and pyrimidine nucleoside phosphorylation in fluoropyrimidine-sensitive and -resistant cell lines of the Novikoff hepatoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-activity relationships for phosphorylation of nucleoside analogs to monophosphates by nucleoside kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Viral thymidine kinases and their relatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human deoxycytidine kinase is located in the cell nucleus

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial basis for immune deficiency. Evidence from purine nucleoside phosphorylase-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of human adenosine kinase cDNA: sequence similarity to microbial ribokinases and fructokinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a peptide antibody against a C-terminal part of human and mouse cytosolic thymidine kinase, which is a marker for cell proliferation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymes of uracil metabolism in the Ehrlich ascites tumour and mammalian liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyrimidine metabolism. II. Enzymatic pathways of uracil anabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the effects of adenosine kinase inhibitors on acute thermal nociception in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The bottleneck in AZT activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitumor mechanisms and metabolism of the novel antitumor nucleoside analogues, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine and 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)uracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fludarabine-mediated inhibition of nucleotide excision repair induces apoptosis in quiescent human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective assays for thymidine kinase 1 and 2 and deoxycytidine kinase and their activities in extracts from human cells and tissues.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual effect of 5-azacytidine on the synthesis of liver ribonucleic acids. Lack of the relationship between metabolic transformation of orotic acid in vitro and its incorporation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uridine kinase: properties, biological significance and chemotherapeutic aspects (a review)

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral neuropathy and antiretroviral drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase 2 clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gemcitabine. A review of its pharmacology and clinical potential in non-small cell lung cancer and pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanism of methotrexate action in inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance to mitochondrial- and Fas-mediated apoptosis in human leukemic cells with acquired resistance to 9-beta-D-arabinofuranosylguanosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assignment of the gene for human adenosine kinase to chromosome 10 using a somatic cell hybrid clone panel

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Substrate specificity of human recombinant mitochondrial deoxyguanosine kinase with cytostatic and antiviral purine and pyrimidine analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of thymidine and uridine on the phosphorylation of 3'-azido-3'-deoxythymidine (zidovudine) in human mononuclear cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleoside transporters of mammalian cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development and molecular characterization of a 2',2'-difluorodeoxycytidine-resistant variant of the human ovarian carcinoma cell line A2780.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxicity of 3'-azido-3'-deoxythymidine correlates with 3'-azidothymidine-5'-monophosphate (AZTMP) levels, whereas anti-human immunodeficiency virus (HIV) activity correlates with 3'-azidothymidine-5'-triphosphate (AZTTP) levels in cultured CEM T

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular distribution of pyrimidine nucleoside phosphorylating activities in rat thymus

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2',3'-Didehydro-3'-deoxythymidine: regulation of its metabolic activation by modulators of thymidine-5'-triphosphate biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of the human deoxyguanosine kinase gene (DGUOK) to chromosome 2p13

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular metabolism of 2',3'-dideoxycytidine, a compound active against human immunodeficiency virus in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uracil metabolism--UMP synthesis from orotic acid or uridine and conversion of uracil to beta-alanine: enzymes and cDNAs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uridine kinase molecular species and uridine uptake in some variants of rat hepatomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New developments in anti-HIV chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine kinase from human liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and expression of the adenosine kinase gene from rat and human tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of deoxyadenosine and nucleoside analog phosphorylation by human placental adenosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Role of Adenosine and 2'-Deoxyadenosine in Mammalian Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of uridine kinase quaternary structure. Dissociation by the inhibitor CTP

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deoxyribonucleoside kinases belonging to the thymidine kinase 2 (TK2)-like group vary significantly in substrate specificity, kinetics and feed-back regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eukaryotic DNA polymerases, a growing family

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uridine kinase activities in developing, adult and neoplastic rat tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nucleoside analogues: mechanisms of drug resistance and reversal strategies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of human dCK suggests strategies to improve anticancer and antiviral therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific toxicity of 2-chlorodeoxyadenosine toward resting and proliferating human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human cytosolic thymidine kinase. Purification and physical characterization of the enzyme from HeLa cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lethal mutagenesis of HIV by mutagenic ribonucleoside analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genotoxicity and mitochondrial damage in human lymphocytic cells chronically exposed to 3'-azido-2',3'-dideoxythymidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic analysis of 2',3'-dideoxycytidine incorporation into cultured human T lymphoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arabinosylguanine is phosphorylated by both cytoplasmic deoxycytidine kinase and mitochondrial deoxyguanosine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The intermediates of aggrecanase-dependent cleavage of aggrecan in rat chondrosarcoma cells treated with interleukin-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/14609716

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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