(Q33351201)

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Genetically polymorphic OCT1: another piece in the puzzle of the variable pharmacokinetics and pharmacodynamics of the opioidergic drug tramadol

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Europe PubMed Central

PubMed publication ID

26 July 2017

Genetically polymorphic OCT1: another piece in the puzzle of the variable pharmacokinetics and pharmacodynamics of the opioidergic drug tramadol (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

pharmacodynamics

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based on heuristic

inferred from title

Irmgard Tegeder

4

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

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J Lötsch

3

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author name string

M V Tzvetkov

1

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

A R Saadatmand

2

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

J C Stingl

5

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

J Brockmöller

6

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Europe PubMed Central

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26 July 2017

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publication date

11 May 2011

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Europe PubMed Central

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26 July 2017

Clinical Pharmacology & Therapeutics

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Europe PubMed Central

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26 July 2017

90

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Europe PubMed Central

PubMed publication ID

26 July 2017

1

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Europe PubMed Central

PubMed publication ID

26 July 2017

143-150

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Europe PubMed Central

PubMed publication ID

26 July 2017

Impact of CYP2D6 genotype on postoperative tramadol analgesia

1 reference

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Interaction of the central analgesic, tramadol, with the uptake and release of 5-hydroxytryptamine in the rat brain in vitro

1 reference

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Tramadol, M1 metabolite and enantiomer affinities for cloned human opioid receptors expressed in transfected HN9.10 neuroblastoma cells

1 reference

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Polymorphic CYP2D6 mediates O-demethylation of the opioid analgesic tramadol

1 reference

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21 January 2018

The metabolism of tramadol by human liver microsomes

1 reference

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21 January 2018

Tramadol as a new probe for cytochrome P450 2D6 phenotyping: a population study

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

21 January 2018

Effects of the CYP2D6 gene duplication on the pharmacokinetics and pharmacodynamics of tramadol

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

21 January 2018

Glucuronidation of racemic O-desmethyltramadol, the active metabolite of tramadol.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

21 January 2018

Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

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Polyspecific organic cation transporters: structure, function, physiological roles, and biopharmaceutical implications

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

21 January 2018

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

21 January 2018

The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

21 January 2018

Identification of genetic variations of the human organic cation transporter hOCT1 and their functional consequences

1 reference

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21 January 2018

Evolutionary conservation predicts function of variants of the human organic cation transporter, OCT1

1 reference

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21 January 2018

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

1 reference

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Influx and efflux transport as determinants of melphalan cytotoxicity: Resistance to melphalan in MDR1 overexpressing tumor cell lines

1 reference

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21 January 2018

Interindividual variation in the pharmacokinetics of Delta9-tetrahydrocannabinol as related to genetic polymorphisms in CYP2C9.

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https://api.crossref.org/works/10.1038%2FCLPT.2011.56

21 January 2018

Bioinformatic and functional analysis of TGFBR1 polymorphisms.

1 reference

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21 January 2018

Allele-specific change of concentration and functional gene dose for the prediction of steady-state serum concentrations of amitriptyline and nortriptyline in CYP2C19 and CYP2D6 extensive and intermediate metabolizers

1 reference

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21 January 2018

Analgesic efficacy of tramadol, pregabalin and ibuprofen in menthol-evoked cold hyperalgesia

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

21 January 2018

Effect of the CYP2D6*10 C188T polymorphism on postoperative tramadol analgesia in a Chinese population

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

21 January 2018

Cellular localization of the organic cation transporters, OCT1 and OCT2, in brain microvessel endothelial cells and its implication for MPTP transport across the blood-brain barrier and MPTP-induced dopaminergic toxicity in rodents.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

21 January 2018

Personalized therapy in pain management: where do we stand?

1 reference

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21 January 2018

The risk of motor vehicle accidents involving drivers with prescriptions for codeine or tramadol.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

21 January 2018

Post-mortem SNP analysis of CYP2D6 gene reveals correlation between genotype and opioid drug (tramadol) metabolite ratios in blood

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

21 January 2018

Physical dependence potential of daily tramadol dosing in humans

1 reference

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21 January 2018

Serotonin syndrome with tramadol and citalopram

1 reference

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21 January 2018

A functional polymorphism in the NAD(P)H oxidase subunit CYBA is related to gene expression, enzyme activity, and outcome in non-Hodgkin lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

21 January 2018

Amelogenin-based sex identification as a strategy to control the identity of DNA samples in genetic association studies

1 reference

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21 January 2018

A comparison of bayesian methods for haplotype reconstruction from population genotype data

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

21 January 2018

CYP2D6 genotyping by a multiplex primer extension reaction.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

21 January 2018

The hypoalgesic effect of tramadol in relation to CYP2D6*

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

7 January 2021

based on heuristic

inferred from DOI database lookup

Is tramadol an antidepressant?

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

7 January 2021

based on heuristic

inferred from DOI database lookup

Enantioselective pharmacokinetics of tramadol in CYP2D6 extensive and poor metabolizers

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

7 January 2021

based on heuristic

inferred from DOI database lookup

Concentrations of tramadol and O-desmethyltramadol enantiomers in different CYP2D6 genotypes

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2011.56

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/CLPT.2011.56

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

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0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 July 2017

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