(Q33562444)

28 July 2017

6 references

28 September 2019

16 November 2019

18 December 2019

22 December 2019

22 December 2020

19 July 2021

Regulation of p63 protein stability via ubiquitin-proteasome pathway (English)

1 reference

ubiquitin-proteasome system

28 July 2017

main subject

0 references

1 reference

28 September 2019

macromolecular substance

1 reference

16 November 2019

1 reference

18 December 2019

2 references

22 December 2019

22 December 2020

1 reference

22 December 2019

proteasome endopeptidase complex

1 reference

19 July 2021

Chenghua Li

1

1 reference

28 July 2017

Zhi-Xiong Xiao

series ordinal

2

1 reference

28 July 2017

language of work or name

English

0 references

publication date

15 April 2014

7 references

BioMed Research International

28 July 2017

28 September 2019

16 November 2019

18 December 2019

22 December 2019

22 December 2020

19 July 2021

7 references

28 July 2017

28 September 2019

16 November 2019

18 December 2019

22 December 2019

22 December 2020

19 July 2021

2014

1 reference

28 July 2017

page(s)

175721

1 reference

Creative Commons Attribution 3.0 Unported

28 July 2017

copyright license

6 references

28 September 2019

16 November 2019

18 December 2019

22 December 2019

22 December 2020

Pin1 modulates p63α protein stability in regulation of cell survival, proliferation and tumor formation

19 July 2021

0 references

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

DNA damage-activated ABL-MyoD signaling contributes to DNA repair in skeletal myoblasts.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

ΔNp63α represses nuclear translocation of PTEN by inhibition of NEDD4-1 in keratinocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Arsenic suppresses cell survival via Pirh2-mediated proteasomal degradation of ΔNp63 protein

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Pirh2 E3 ubiquitin ligase modulates keratinocyte differentiation through p63.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

TAp63 is a master transcriptional regulator of lipid and glucose metabolism

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

DNA damage down-regulates ΔNp63α and induces apoptosis independent of wild type p53.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Regulation of skin aging and heart development by TAp63.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

c-Abl phosphorylation of ΔNp63α is critical for cell viability

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

DNA damage in oocytes induces a switch of the quality control factor TAp63α from dimer to tetramer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

ΔNp63α is an oncogene that targets chromatin remodeler Lsh to drive skin stem cell proliferation and tumorigenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

DeltaNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

MDM2 and Fbw7 cooperate to induce p63 protein degradation following DNA damage and cell differentiation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Cables1 protects p63 from proteasomal degradation to ensure deletion of cells after genotoxic stress

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Regulation of p53 family member isoform DeltaNp63alpha by the nuclear factor-kappaB targeting kinase IkappaB kinase beta

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

TAp63 induces senescence and suppresses tumorigenesis in vivo

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Identification and functional characterization of two new transcriptional variants of the human p63 gene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Plk1 regulates liver tumor cell death by phosphorylation of TAp63.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

TAp63 prevents premature aging by promoting adult stem cell maintenance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Stxbp4 regulates DeltaNp63 stability by suppression of RACK1-dependent degradation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Homeodomain protein Dlx3 induces phosphorylation-dependent p63 degradation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Phosphorylation and stabilization of TAp63gamma by IkappaB kinase-beta

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

p63 Is essential for the proliferative potential of stem cells in stratified epithelia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

p63: the phantom of the tumor suppressor

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

The E3 ubiquitin ligase Itch controls the protein stability of p63

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Itch/AIP4 associates with and promotes p63 protein degradation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

p63 regulates an adhesion programme and cell survival in epithelial cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

DNA-binding and transactivation activities are essential for TAp63 protein degradation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

TAp63alpha induces apoptosis by activating signaling via death receptors and mitochondria

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

DeltaNp63alpha up-regulates the Hsp70 gene in human cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

The ubiquitin-protein ligase Itch regulates p73 stability

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

The protein stability and transcriptional activity of p63alpha are regulated by SUMO-1 conjugation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

RACK1 and stratifin target DeltaNp63alpha for a proteasome degradation in head and neck squamous cell carcinoma cells upon DNA damage

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Gadd45a regulates matrix metalloproteinases by suppressing DeltaNp63alpha and beta-catenin via p38 MAP kinase and APC complex activation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

p73 and p63 protein stability: the way to regulate function?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Differential expression of p63 isoforms in normal tissues and neoplastic cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

The human MDM2 oncoprotein increases the transcriptional activity and the protein level of the p53 homolog p63.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

p63 Gene mutations in eec syndrome, limb-mammary syndrome, and isolated split hand-split foot malformation suggest a genotype-phenotype correlation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

p53 associates with and targets Delta Np63 into a protein degradation pathway

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

AIS is an oncogene amplified in squamous cell carcinoma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

p63 is a p53 homologue required for limb and epidermal morphogenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Cloning and functional analysis of human p51, which structurally and functionally resembles p53

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

A new human p53 homologue

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4009111

Unique domain functions of p63 isotypes that differentially regulate distinct aspects of epidermal homeostasis

14 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F175721

Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F175721

Quality control in oocytes: domain-domain interactions regulate the activity of p63.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F175721

Perp is a p63-regulated gene essential for epithelial integrity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F175721

p53 gene family p51(p63)-encoded, secondary transactivator p51B(TAp63alpha) occurs without forming an immunoprecipitable complex with MDM2, but responds to genotoxic stress by accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F175721

Destabilization of DeltaNp63alpha by Nedd4-mediated ubiquitination and Ubc9-mediated sumoylation, and its implications on dorsoventral patterning of the zebrafish embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F175721

HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F175721

The Hippo pathway kinase Lats2 prevents DNA damage-induced apoptosis through inhibition of the tyrosine kinase c-Abl

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F175721

A complex between FAK, RACK1, and PDE4D5 controls spreading initiation and cancer cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F175721

p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F175721

The promyelocytic leukaemia protein tumour suppressor functions as a transcriptional regulator of p63.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F175721

MDM2 and MDMX can interact differently with ARF and members of the p53 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2014%2F175721

Inactivation of the p53-homologue p73 by the mdm2-oncoprotein

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24822180

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1155/2014/175721

1 reference

28 July 2017

1 reference

28 July 2017

1 reference