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Allosteric regulation of protease activity by small molecules.
scientific article
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4356121
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20539873%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
review article
1 reference
stated in
Europe PubMed Central
title
Allosteric regulation of protease activity by small molecules
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4356121
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20539873%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
author
Aimee Shen
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4356121
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20539873%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
author name string
Aimee Shen
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
20539873
retrieved
28 July 2017
publication date
10 June 2010
1 reference
stated in
Europe PubMed Central
PMC publication ID
4356121
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20539873%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
published in
Molecular BioSystems
1 reference
stated in
Europe PubMed Central
PMC publication ID
4356121
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20539873%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
volume
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
4356121
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20539873%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
issue
8
1 reference
stated in
Europe PubMed Central
PMC publication ID
4356121
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20539873%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
page(s)
1431-1443
1 reference
stated in
Europe PubMed Central
PMC publication ID
4356121
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20539873%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
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Communication between the active sites and dimer interface of a herpesvirus protease revealed by a transition-state inhibitor
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
21 June 2018
myo-Inositol-1,2,3,4,5,6-hexakisphosphate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
21 June 2018
Cellular uptake of Clostridium difficile toxin B. Translocation of the N-terminal catalytic domain into the cytosol of eukaryotic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
21 June 2018
Mutation patterns and structural correlates in human immunodeficiency virus type 1 protease following different protease inhibitor treatments
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
21 June 2018
Evolutionarily conserved networks of residues mediate allosteric communication in proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
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21 June 2018
Irreversible inhibitors of serine, cysteine, and threonine proteases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
21 June 2018
Impact of recombinant DNA technology and protein engineering on structure-based drug design: case studies of HIV-1 and HCMV proteases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
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21 June 2018
Conformational change coupling the dimerization and activation of KSHV protease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
21 June 2018
Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
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21 June 2018
Molecular mechanism for dimerization to regulate the catalytic activity of human cytomegalovirus protease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
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21 June 2018
Evolutionary lines of cysteine peptidases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
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21 June 2018
A common enzyme connects notch signaling and Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
21 June 2018
The genetics and molecular pathology of Alzheimer's disease: roles of amyloid and the presenilins
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
21 June 2018
Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
21 June 2018
Peptide exosite inhibitors of factor VIIa as anticoagulants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
21 June 2018
The herpesvirus proteases as targets for antiviral chemotherapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
21 June 2018
Auto-inactivation by cleavage within the dimer interface of Kaposi's sarcoma-associated herpesvirus protease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
21 June 2018
Induction of the bovine trypsinogen-trypsin transition by peptides sequentially similar to the N-terminus of trypsin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
21 June 2018
Crystal structures of a ligand-free and malonate-bound human caspase-1: implications for the mechanism of substrate binding.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1039%2FC003913F
retrieved
21 January 2018
Dynamic activation of an allosteric regulatory protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
30 October 2018
Peptidic small molecule activators of the stress sensor DegS.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
30 October 2018
Autocatalytic processing of Clostridium difficile toxin B. Binding of inositol hexakisphosphate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
30 October 2018
Auto-catalytic cleavage of Clostridium difficile toxins A and B depends on cysteine protease activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
30 October 2018
Flipping the safety catch of procaspase-3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
30 October 2018
Identification of early intermediates of caspase activation using selective inhibitors and activity-based probes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
30 October 2018
Enzyme dynamics during catalysis measured by NMR spectroscopy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
30 October 2018
Characterization of the cleavage site and function of resulting cleavage fragments after limited proteolysis of Clostridium difficile toxin B (TcdB) by host cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
30 October 2018
Mutagenesis of the Clostridium difficile toxin B gene and effect on cytotoxic activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4356121
retrieved
30 October 2018
Small molecules not direct activators of caspases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20539873
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Commonly used caspase inhibitors designed based on substrate specificity profiles lack selectivity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20539873
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
MEROPS: the peptidase database
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20539873
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Two-state allosteric behavior in a single-domain signaling protein
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20539873
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1039/C003913F
1 reference
stated in
Europe PubMed Central
PMC publication ID
4356121
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20539873%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
PMC publication ID
4356121
1 reference
stated in
Europe PubMed Central
PMC publication ID
4356121
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20539873%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
PubMed publication ID
20539873
1 reference
stated in
Europe PubMed Central
PMC publication ID
4356121
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20539873%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 February 2020
ResearchGate publication ID
44665313
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