(Q33648434)

28 July 2017

title

Vaccinia virus protein F1L is a caspase-9 inhibitor (English)

1 reference

28 July 2017

Vaccinia virus

1 reference

Dayong Zhai

1

1 reference

28 July 2017

Eric Yu

2

1 reference

28 July 2017

Chaofang Jin

3

1 reference

28 July 2017

Kate Welsh

4

1 reference

28 July 2017

Chung-wei Shiau

5

1 reference

28 July 2017

Lili Chen

6

1 reference

28 July 2017

Guy S Salvesen

7

1 reference

28 July 2017

Robert Liddington

8

1 reference

28 July 2017

John C Reed

9

1 reference

28 July 2017

language of work or name

English

0 references

publication date

18 December 2009

1 reference

Journal of Biological Chemistry

28 July 2017

published in

1 reference

28 July 2017

volume

285

1 reference

28 July 2017

issue

8

1 reference

28 July 2017

page(s)

5569-5580

1 reference

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

28 July 2017

cites work

1 reference

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Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligands

21 June 2018

1 reference

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Autophagy in the Pathogenesis of Disease

21 June 2018

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Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1

21 June 2018

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The apoptosome: signalling platform of cell death

21 June 2018

1 reference

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Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

The vaccinia virus protein F1L interacts with Bim and inhibits activation of the pro-apoptotic protein Bax

21 June 2018

1 reference

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Apoptosome: a platform for the activation of initiator caspases

21 June 2018

1 reference

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The apoptosome activates caspase-9 by dimerization

21 June 2018

1 reference

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Interaction of F1L with the BH3 domain of Bak is responsible for inhibiting vaccinia-induced apoptosis

21 June 2018

1 reference

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Near death experiences: poxvirus regulation of apoptotic death

21 June 2018

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The vaccinia virus F1L protein interacts with the proapoptotic protein Bak and inhibits Bak activation

21 June 2018

1 reference

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Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1.

21 June 2018

1 reference

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Structure of the apoptotic protease-activating factor 1 bound to ADP

21 June 2018

1 reference

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Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

21 June 2018

1 reference

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Humanin binds and nullifies Bid activity by blocking its activation of Bax and Bak

21 June 2018

1 reference

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Viral proteins targeting mitochondria: controlling cell death

21 June 2018

1 reference

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Caspase activation, inhibition, and reactivation: a mechanistic view

21 June 2018

1 reference

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Association of active caspase 8 with the mitochondrial membrane during apoptosis: potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death

21 June 2018

1 reference

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Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes

21 June 2018

1 reference

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Cell death: critical control points

21 June 2018

1 reference

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Mechanisms of caspase activation

21 June 2018

1 reference

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Vaccinia virus encodes a previously uncharacterized mitochondrial-associated inhibitor of apoptosis

21 June 2018

1 reference

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Characterization of the anti-apoptotic mechanism of Bcl-B

21 June 2018

1 reference

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The CD95(APO-1/Fas) DISC and beyond

21 June 2018

1 reference

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A unified model for apical caspase activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

Mechanism of XIAP-mediated inhibition of caspase-9

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

Mitochondrially localized active caspase-9 and caspase-3 result mostly from translocation from the cytosol and partly from caspase-mediated activation in the organelle. Lack of evidence for Apaf-1-mediated procaspase-9 activation in the mitochondria

21 June 2018

1 reference

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Viral homologs of BCL-2: role of apoptosis in the regulation of virus infection

21 June 2018

1 reference

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Poxviruses and apoptosis: a time to die.

21 June 2018

1 reference

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Reprieval from execution: the molecular basis of caspase inhibition

21 June 2018

1 reference

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Dimer formation drives the activation of the cell death protease caspase 9

21 June 2018

1 reference

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Cop, a caspase recruitment domain-containing protein and inhibitor of caspase-1 activation processing

21 June 2018

1 reference

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Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex

21 June 2018

1 reference

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A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

21 June 2018

1 reference

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Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes

21 June 2018

1 reference

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ICEBERG: a novel inhibitor of interleukin-1beta generation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

Purification and use of recombinant inhibitor of apoptosis proteins as caspase inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

Caspase-9 and APAF-1 form an active holoenzyme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

Caspases: preparation and characterization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

Caspase-9 can be activated without proteolytic processing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

Mitochondrial release of caspase-2 and -9 during the apoptotic process

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

Immunohistochemical analysis of in vivo patterns of expression of CPP32 (Caspase-3), a cell death protease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

Target protease specificity of the viral serpin CrmA. Analysis of five caspases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820784

Modified vaccinia virus Ankara protein F1L is a novel BH3-domain-binding protein and acts together with the early viral protein E3L to block virus-associated apoptosis

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M109.078113

Pre-processed caspase-9 contained in mitochondria participates in apoptosis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M109.078113

Apaf-1 oligomerizes into biologically active approximately 700-kDa and inactive approximately 1.4-MDa apoptosome complexes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20022954

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20022954

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.078113

1 reference

28 July 2017

1 reference

28 July 2017

1 reference