(Q33688799)

28 July 2017

1 reference

title

The biochemistry of Alzheimer's disease (English)

1 reference

28 July 2017

0 references

Stege GJ

1

1 reference

28 July 2017

Bosman GJ

series ordinal

2

1 reference

28 July 2017

1 June 1999

1 reference

28 July 2017

1 reference

28 July 2017

14

1 reference

28 July 2017

6

1 reference

28 July 2017

437-446

1 reference

https://scigraph.springernature.com/pub.10.2165/00002512-199914060-00004

28 July 2017

0 references

cites work

NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation

1 reference

12 December 2020

Alzheimer-associated presenilins 1 and 2: neuronal expression in brain and localization to intracellular membranes in mammalian cells.

1 reference

12 December 2020

Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation

1 reference

12 December 2020

Shift from fetal-type to Alzheimer-type phosphorylated Tau proteins in SKNSH-SY 5Y cells treated with okadaic acid.

1 reference

12 December 2020

Apolipoprotein E is localized to the cytoplasm of human cortical neurons: a light and electron microscopic study

1 reference

12 December 2020

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

12 December 2020

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

12 December 2020

Microglia in degenerative neurological disease.

1 reference

12 December 2020

Two-dimensional characterization of paired helical filament-tau from Alzheimer's disease: demonstration of an additional 74-kDa component and age-related biochemical modifications.

1 reference

12 December 2020

Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

1 reference

12 December 2020

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

12 December 2020

Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease

1 reference

12 December 2020

Expression of alpha B-crystallin in Alzheimer's disease.

1 reference

12 December 2020

Acetylcholinesterase accelerates assembly of amyloid-beta-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme.

1 reference

12 December 2020

Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro

1 reference

12 December 2020

In situ evidence for DNA fragmentation in Huntington's disease striatum and Alzheimer's disease temporal lobes

1 reference

12 December 2020

Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein

1 reference

12 December 2020

Evidence that the precursor protein of non-A beta component of Alzheimer's disease amyloid (NACP) has an extended structure primarily composed of random-coil.

1 reference

12 December 2020

Ultrastructure of the cells forming amyloid fibers in Alzheimer disease and scrapie

1 reference

12 December 2020

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

1 reference

12 December 2020

Alpha 1-antichymotrypsin regulates Alzheimer beta-amyloid peptide fibril formation

1 reference

12 December 2020

Receptor-mediated activation of G proteins is reduced in postmortem brains from Alzheimer's disease patients.

1 reference

12 December 2020

The Alzheimer amyloid precursor proteoglycan (appican) is present in brain and is produced by astrocytes but not by neurons in primary neural cultures.

1 reference

12 December 2020

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

12 December 2020

Evidence for a six-transmembrane domain structure of presenilin 1.

1 reference

12 December 2020

Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.

1 reference

12 December 2020

Plaques, tangles and dementia. A quantitative study.

1 reference

12 December 2020

Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease

1 reference

12 December 2020

The seven-transmembrane spanning topography of the Alzheimer disease-related presenilin proteins in the plasma membranes of cultured cells

1 reference

12 December 2020

Apo E allele frequencies in Alzheimer's disease, Lewy body dementia, Alzheimer's disease with cerebrovascular disease and vascular dementia

1 reference

12 December 2020

ApoE-4 and age at onset of Alzheimer's disease: the NIMH genetics initiative.

1 reference

12 December 2020

On the spurious endoproteolytic processing of the presenilin proteins in cultured cells and tissues

1 reference

12 December 2020

Image analysis of beta-amyloid load in Alzheimer's disease and relation to dementia severity

1 reference

12 December 2020

Frameshift mutants of beta amyloid precursor protein and ubiquitin-B in Alzheimer's and Down patients

1 reference

12 December 2020

beta-Amyloid neurotoxicity: a discussion of in vitro findings

1 reference

12 December 2020

An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistence of fibrillar A beta-amyloid in rat brain

1 reference

12 December 2020

Differential induction of immediate early gene proteins in cultured neurons by beta-amyloid (A beta): association of c-Jun with A beta-induced apoptosis.

1 reference

12 December 2020

Presenilins, amyloid-beta and Alzheimer's disease

1 reference

12 December 2020

Apolipoprotein E increases the fibrillogenic potential of synthetic peptides derived from Alzheimer's, gelsolin and AA amyloids

1 reference

12 December 2020

Paired helical filament-like phosphorylation of tau, deposition of beta/A4-amyloid and memory impairment in rat induced by chronic inhibition of phosphatase 1 and 2A

1 reference

12 December 2020

Up-regulation of Bcl-2 is associated with neuronal DNA damage in Alzheimer's disease.

1 reference

12 December 2020

Metabotropic glutamate receptors increase amyloid precursor protein processing in astrocytes: inhibition by cyclic AMP.

1 reference

12 December 2020

The synaptic protein NACP is abnormally expressed during the progression of Alzheimer's disease

1 reference

12 December 2020

The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

1 reference

12 December 2020

Cell death in Alzheimer's disease evaluated by DNA fragmentation in situ

1 reference

12 December 2020

Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor.

1 reference

12 December 2020

Presenilins: genes for life and death

1 reference

12 December 2020

Neuritic pathology and dementia in Alzheimer's disease.

1 reference

12 December 2020

The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways

1 reference

12 December 2020

Aspartate residue 7 in amyloid beta-protein is critical for classical complement pathway activation: implications for Alzheimer's disease pathogenesis

1 reference

12 December 2020

Alzheimer presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation

1 reference

12 December 2020

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

12 December 2020

Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration

1 reference

12 December 2020

Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans.

1 reference

12 December 2020

Microglia: Intrinsic immuneffector cell of the brain

1 reference

12 December 2020

Acute phase proteins are present in amorphous plaques in the cerebral but not in the cerebellar cortex of patients with Alzheimer's disease.

1 reference

12 December 2020

The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease

1 reference

12 December 2020

Alzheimer’s Disease and Cellular Aging: Membrane-Related Events as Clues to Primary Mechanisms

1 reference

12 December 2020

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

1 reference

12 December 2020

Apolipoprotein E alleles as risk factors in Alzheimer's disease

1 reference

12 December 2020

Normal and abnormal biology of the beta-amyloid precursor protein

1 reference

12 December 2020

Characterization of the precursor protein of the non-A beta component of senile plaques (NACP) in the human central nervous system.

1 reference

12 December 2020

Neuroglial-mediated immunoinflammatory responses in Alzheimer's disease: complement activation and therapeutic approaches

1 reference

12 December 2020

The genetics of Alzheimer's disease

1 reference

12 December 2020

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

1 reference

12 December 2020

Apolipoprotein E and Alzheimer's disease: a review of recent studies

1 reference

12 December 2020

Pattern of brain destruction in Parkinson's and Alzheimer's diseases.

1 reference

12 December 2020

Alzheimer's amyloid precursor protein is expressed on the surface of hematopoietic cells upon activation.

1 reference

12 December 2020

Amyloid beta protein primes cultured rat microglial cells for an enhanced phorbol 12-myristate 13-acetate-induced respiratory burst activity

1 reference

12 December 2020

Alzheimer transgenic mouse models come of age.

1 reference

12 December 2020

Interaction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer disease

1 reference

12 December 2020

Immunohistochemical evidence for apoptosis in Alzheimer's disease.

1 reference

12 December 2020

Non-A beta component of Alzheimer's disease amyloid (NAC) is amyloidogenic

1 reference

12 December 2020

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

1 reference

12 December 2020

Altered presynaptic protein NACP is associated with plaque formation and neurodegeneration in Alzheimer's disease

1 reference

12 December 2020

Processing of presenilin 1 in brains of patients with Alzheimer's disease and controls.

1 reference

12 December 2020

The phosphorylation of tau: a critical stage in neurodevelopment and neurodegenerative processes.

1 reference

12 December 2020

Mechanisms of neuronal death in brain aging and Alzheimer's disease: role of endocrine-mediated calcium dyshomeostasis

1 reference

12 December 2020

beta-Amyloid Ca(2+)-channel hypothesis for neuronal death in Alzheimer disease

1 reference

12 December 2020

Phospholipase C isozymes in the human brain and their changes in Alzheimer's disease.

1 reference

12 December 2020

In vivo and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesis

1 reference

12 December 2020

Proteins immunologically related to erythrocyte anion transporter band 3 are altered in brain areas affected by Alzheimer's disease.

1 reference

12 December 2020

Microglia: a sensor for pathological events in the CNS

1 reference

12 December 2020

Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E.

1 reference

12 December 2020

1 reference

12 December 2020

Degradation of proteins in the membrane-cytoskeleton complex in Alzheimer's disease. Might amyloidogenic APP processing be just the tip of the iceberg?

1 reference

12 December 2020

Neurocytopathic effects of beta-amyloid-stimulated monocytes: a potential mechanism for central nervous system damage in Alzheimer disease

1 reference

12 December 2020

Amyloid fibril toxicity in Alzheimer's disease and diabetes

1 reference

12 December 2020

Apoptosis mediated neurotoxicity induced by chronic application of beta amyloid fragment 25-35.

1 reference

12 December 2020

The neuropathological diagnosis of Alzheimer disease.

1 reference

12 December 2020

Neurodegeneration induced by beta-amyloid peptides in vitro: the role of peptide assembly state

1 reference

12 December 2020

Physiological production of the beta-amyloid protein and the mechanism of Alzheimer's disease

1 reference

12 December 2020

Membrane alterations in Alzheimer's disease and aging

1 reference

12 December 2020

Inflammation, A beta deposition, and neurofibrillary tangle formation as correlates of Alzheimer's disease neurodegeneration.

1 reference

12 December 2020

Age, neurofibrillary changes, A beta-amyloid and the onset of Alzheimer's disease

1 reference

12 December 2020

Correlates of p53- and Fas (CD95)-mediated apoptosis in Alzheimer's disease.

1 reference

12 December 2020

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

12 December 2020

Apoptosis is induced by beta-amyloid in cultured central nervous system neurons

1 reference

12 December 2020

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies

1 reference

12 December 2020

Isoform-specific binding of apolipoprotein E to beta-amyloid

1 reference

12 December 2020

Alzheimer's disease. Clinical molecular genetics

1 reference

12 December 2020

Concentration-dependent inhibitory effects of apolipoprotein E on Alzheimer's beta-amyloid fibril formation in vitro.

1 reference

12 December 2020

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

1 reference

12 December 2020

Down's syndrome and Alzheimer's disease: a review

1 reference

12 December 2020

10.2165/00002512-199914060-00004

Identifiers

DOI

1 reference

Dimensions Publication ID

28 July 2017

1006041795

0 references

Fatcat ID

release_enb7a2sh25f2dl2zt7ab6b4x2u

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/enb7a2sh25f2dl2zt7ab6b4x2u

24 November 2022

mapped directly with Wikidata item

1 reference