(Q33698044)

28 July 2017

title

Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin gene (English)

1 reference

28 July 2017

Shelley L Berger

5

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author name string

Yanlin Yu

1

1 reference

28 July 2017

Pingyao Zeng

2

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28 July 2017

Jingbo Xiong

3

1 reference

28 July 2017

Ziyang Liu

4

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28 July 2017

Glenn Merlino

6

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28 July 2017

language of work or name

English

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publication date

13 September 2010

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28 July 2017

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28 July 2017

volume

5

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28 July 2017

issue

9

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28 July 2017

page(s)

e12710

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Creative Commons CC0 License

28 July 2017

copyright license

start time

13 September 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

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The membrane cytoskeletal crosslinker ezrin is required for metastasis of breast carcinoma cells

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Src-dependent ezrin phosphorylation in adhesion-mediated signaling

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The membrane-cytoskeleton linker ezrin is necessary for osteosarcoma metastasis

21 June 2018

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Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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DNA methylation patterns and epigenetic memory

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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ERM proteins in cell adhesion and membrane dynamics

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938331

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938331

Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938331

Alterations in DNA methylation: a fundamental aspect of neoplasia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938331

Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938331

Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938331

Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938331

Chromatin as an essential part of the transcriptional mechanim

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938331

Merlin and ERM proteins: unappreciated roles in cancer development?

21 June 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012710

Ezrin immunoreactivity is associated with increasing malignancy of astrocytic tumors but is absent in oligodendrogliomas

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012710

The homeoprotein six1 transcriptionally activates multiple protumorigenic genes but requires ezrin to promote metastasis.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012710

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012710

Epigenetic up-regulation of C-C chemokine receptor 7 and C-X-C chemokine receptor 4 expression in melanoma cells

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012710

Epigenetic regulation of c-ROS receptor tyrosine kinase expression in malignant gliomas

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012710

Dependence of histone modifications and gene expression on DNA hypermethylation in cancer.

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2938331

Gene expression patterns associated with the metastatic phenotype in rodent and human tumors

30 October 2018

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12 December 2020

Constitutive c-Met signaling through a nonautocrine mechanism promotes metastasis in a transgenic transplantation model

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12 December 2020

High levels of ezrin expressed by human pancreatic adenocarcinoma cell lines with high metastatic potential

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12 December 2020

Ezrin in primary cutaneous melanoma

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12 December 2020

Epigenetic silencing of the PTEN gene in melanoma

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12 December 2020

The fundamental role of epigenetic events in cancer

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12 December 2020

10.1371/JOURNAL.PONE.0012710

Identifiers

DOI

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28 July 2017

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28 July 2017

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