(Q33707527)

English

Human Immunodeficiency virus type 1 Nef potently induces apoptosis in primary human brain microvascular endothelial cells via the activation of caspases

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scholarly article

1 reference

Europe PubMed Central

28 July 2017

Human Immunodeficiency virus type 1 Nef potently induces apoptosis in primary human brain microvascular endothelial cells via the activation of caspases (English)

1 reference

Europe PubMed Central

28 July 2017

0 references

apoptotic process

1 reference

based on heuristic

inferred from title

Roger J. Pomerantz

6

object named as

Roger J Pomerantz

1 reference

Europe PubMed Central

28 July 2017

author name string

Edward A Acheampong

1

1 reference

Europe PubMed Central

28 July 2017

Zahida Parveen

2

1 reference

Europe PubMed Central

28 July 2017

Lois W Muthoga

3

1 reference

Europe PubMed Central

28 July 2017

Mehrnush Kalayeh

4

1 reference

Europe PubMed Central

28 July 2017

Muhammad Mukhtar

5

1 reference

Europe PubMed Central

28 July 2017

publication date

1 April 2005

1 reference

Europe PubMed Central

28 July 2017

Journal of Virology

1 reference

Europe PubMed Central

28 July 2017

79

1 reference

Europe PubMed Central

28 July 2017

7

1 reference

Europe PubMed Central

28 July 2017

4257-4269

1 reference

Europe PubMed Central

28 July 2017

The pathophysiology of mitochondrial cell death

1 reference

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21 June 2018

Mechanisms of apoptosis

1 reference

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21 June 2018

Virus-induced neuronal apoptosis as pathological and protective responses of the host

1 reference

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21 June 2018

Apoptosis, subcellular particles, and autoimmunity.

1 reference

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21 June 2018

The domains of apoptosis: a genomics perspective

1 reference

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21 June 2018

Contribution of proteoglycans to human immunodeficiency virus type 1 brain invasion

1 reference

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21 June 2018

HIV-1-mediated apoptosis of neuronal cells: Proximal molecular mechanisms of HIV-1-induced encephalopathy

1 reference

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21 June 2018

Extracellular Nef protein targets CD4+ T cells for apoptosis by interacting with CXCR4 surface receptors

1 reference

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21 June 2018

Cell-type-specific gene delivery into neuronal cells in vitro and in vivo

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21 June 2018

Monocyte/macrophage traffic in HIV and SIV encephalitis

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21 June 2018

Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development

1 reference

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21 June 2018

Mechanisms of CD4+ T lymphocyte cell death in human immunodeficiency virus infection and AIDS

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21 June 2018

Apoptosis in HIV-1 infection.

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21 June 2018

Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation

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21 June 2018

Ethanol strongly potentiates apoptosis induced by HIV-1 proteins in primary human brain microvascular endothelial cells

1 reference

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21 June 2018

Switching from life to death: the Miz-ing link between Myc and p53.

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21 June 2018

Microglia in human immunodeficiency virus-associated neurodegeneration.

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21 June 2018

The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis

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21 June 2018

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21 June 2018

p53AIP1 regulates the mitochondrial apoptotic pathway.

1 reference

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21 June 2018

Lentiviral expression of HIV-1 Vpr induces apoptosis in human neurons

1 reference

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21 June 2018

Human immunodeficiency virus type 1 Nef binds to tumor suppressor p53 and protects cells against p53-mediated apoptosis.

1 reference

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21 June 2018

HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals

1 reference

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21 June 2018

Structure--function relationships in HIV-1 Nef.

1 reference

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21 June 2018

A structural view of mitochondria-mediated apoptosis

1 reference

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21 June 2018

HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell

1 reference

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21 June 2018

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

1 reference

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21 June 2018

HIV and SIV Nef modulate signal transduction and protein sorting in T cells

1 reference

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21 June 2018

Differences in cytokine and chemokine responses during neurological disease induced by polytropic murine retroviruses Map to separate regions of the viral envelope gene

1 reference

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21 June 2018

HIV type 1 nef gene inhibits tumor necrosis factor alpha-induced apoptosis and promotes cell proliferation through the action of MAPK and JNK in human glial cells

1 reference

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21 June 2018

Apoptosis enhancement by the HIV-1 Nef protein.

1 reference

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21 June 2018

Development of an in vitro blood-brain barrier model to study molecular neuropathogenesis and neurovirologic disorders induced by human immunodeficiency virus type 1 infection.

1 reference

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21 June 2018

Human immunodeficiency virus type 1 Vpr induces apoptosis in human neuronal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1061575

21 June 2018

HIV-1 Nef: a critical factor in viral-induced pathogenesis

1 reference

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21 June 2018

Spleen necrosis virus-derived C-type retroviral vectors for gene transfer to quiescent cells

1 reference

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21 June 2018

Recombinant nef HIV-IIIB protein is toxic to human neurons in culture

1 reference

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21 June 2018

p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

1 reference

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21 June 2018

Anti-human immunodeficiency virus type 1 gene therapy in human central nervous system-based cells: an initial approach against a potential viral reservoir

1 reference

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21 June 2018

Fractalkine modulates TNF-alpha secretion and neurotoxicity induced by microglial activation

1 reference

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21 June 2018

From receptors to stress-activated MAP kinases

1 reference

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21 June 2018

Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia

1 reference

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21 June 2018

The numerous effector functions of Nef.

1 reference

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21 June 2018

The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1061575

21 June 2018

Regulation of human immunodeficiency virus type 1 infectivity by the ERK mitogen-activated protein kinase signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1061575

21 June 2018

Unraveling the mechanisms of neurotoxicity in HIV type 1-associated dementia: inhibition of neuronal synaptic transmission by macrophage secretory products

1 reference

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21 June 2018

Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx

1 reference

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21 June 2018

Binding of c-Raf1 kinase to a conserved acidic sequence within the carboxyl-terminal region of the HIV-1 Nef protein

1 reference

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21 June 2018

HIV-1 Nef binding protein expressed on the surface of murine blood cells

1 reference

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21 June 2018

AIDS pathogenesis: the role of accessory gene mutations, leading to formation of long-lived persistently infected cells and/or apoptosis-inducing HIV-1 particles.

1 reference

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21 June 2018

Nef protein of HIV-1 induces apoptotic cytolysis of murine lymphoid cells independently of CD95 (Fas) and its suppression by serine/threonine protein kinase inhibitors

1 reference

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21 June 2018

Lysis of HIV-1-infected cells and inhibition of viral replication by universal receptor T cells

1 reference

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21 June 2018

Cytotoxic activity of the amino-terminal region of HIV type 1 Nef protein

1 reference

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21 June 2018

Daxx, a novel Fas-binding protein that activates JNK and apoptosis

1 reference

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21 June 2018

Evasion of cytotoxic T lymphocyte (CTL) responses by nef-dependent induction of Fas ligand (CD95L) expression on simian immunodeficiency virus-infected cells.

1 reference

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21 June 2018

Processing/activation of at least four interleukin-1beta converting enzyme-like proteases occurs during the execution phase of apoptosis in human monocytic tumor cells

1 reference

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21 June 2018

In vitro cytocidal effects of human immunodeficiency virus type 1 Nef on unprimed human CD4+ T cells without MHC restriction

1 reference

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21 June 2018

Synergy between the Mos/mitogen-activated protein kinase pathway and loss of p53 function in transformation and chromosome instability

1 reference

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21 June 2018

Apoptosis induced by HIV-1 infection of the central nervous system

1 reference

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21 June 2018

Clustered localization of oligomeric Nef protein of human immunodeficiency virus type 1 on the cell surface

1 reference

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21 June 2018

Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95

1 reference

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21 June 2018

Human immunodeficiency virus type 1 Nef protein on the cell surface is cytocidal for human CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1061575

21 June 2018

Soluble Nef antigen of HIV-1 is cytotoxic for human CD4+ T cells

1 reference

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21 June 2018

Human immunodeficiency virus type 1 Nef binds directly to Lck and mitogen-activated protein kinase, inhibiting kinase activity

1 reference

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21 June 2018

Human immunodeficiency virus encephalitis in SCID mice.

1 reference

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21 June 2018

Vacuolar myelopathy in transgenic mice expressing human immunodeficiency virus type 1 proteins under the regulation of the myelin basic protein gene promoter

1 reference

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21 June 2018

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

1 reference

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21 June 2018

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

1 reference

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21 June 2018

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

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21 June 2018

Cancer therapy and p53.

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21 June 2018

Human immunodeficiency virus type 1 infection of the nervous system: pathogenetic mechanisms

1 reference

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21 June 2018

Spontaneous and inducible epidermal hyperplasia in transgenic mice expressing HIV-1 Nef.

1 reference

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21 June 2018

Expression of human immunodeficiency virus type 1 in the nervous system of transgenic mice leads to neurological disease

1 reference

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21 June 2018

Cytokines, inflammation, and brain injury: role of tumor necrosis factor-alpha.

1 reference

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21 June 2018

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

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21 June 2018

Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes

1 reference

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21 June 2018

Molecular mechanisms of APO-1/Fas(CD95)-mediated apoptosis in tolerance and AIDS.

1 reference

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21 June 2018

A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

1 reference

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21 June 2018

Viral dynamics in human immunodeficiency virus type 1 infection

1 reference

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21 June 2018

Fas ligand mediates activation-induced cell death in human T lymphocytes

1 reference

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21 June 2018

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

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21 June 2018

Neuronal apoptosis in HIV infection in adults

1 reference

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21 June 2018

Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients

1 reference

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21 June 2018

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1 reference

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21 June 2018

Ordered appearance of human immunodeficiency virus type 1 nucleic acids following high multiplicity infection of macrophages

1 reference

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21 June 2018

Caspase-dependent and -independent T-cell death pathways in pathogenic simian immunodeficiency virus infection: relationship to disease progression

1 reference

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30 October 2018

Productive HIV-2 infection in the brain is restricted to macrophages/microglia.

1 reference

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30 October 2018

HIV-1 Tat-mediated apoptosis in human brain microvascular endothelial cells

1 reference

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30 October 2018

Preferential topography of proteins regulating vascularization and apoptosis in a MX1 xenotransplant after treatment with hypoxia, hyperthermia, ifosfamide, and irradiation.

1 reference

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30 October 2018

Primary isolated human brain microvascular endothelial cells express diverse HIV/SIV-associated chemokine coreceptors and DC-SIGN and L-SIGN.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1061575

30 October 2018

Involvement of brain cytokines in the neurobehavioral disturbances induced by HIV-1 glycoprotein120.

1 reference

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30 October 2018

Effect of N-acetylcysteine and L-NAME on aluminium phosphide induced cardiovascular toxicity in rats.

1 reference

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30 October 2018

HIV Nef increases T cell ERK MAP kinase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1061575

30 October 2018

HIV-1 penetrates coronary artery endothelial cells by transcytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1061575

30 October 2018

A novel mouse model of HIV-1 disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1061575

30 October 2018

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1061575

30 October 2018

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1061575

30 October 2018

HIV-1 Nef protein-induced apoptotic cytolysis of a broad spectrum of uninfected human blood cells independently of CD95(Fas).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1061575

30 October 2018

HIV type 1 Nef perturbs eye lens development in transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1061575

30 October 2018

Intrathecal IgG synthesis and albumin leakage are increased in subjects with HIV-1 neurologic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1061575

30 October 2018

Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1061575

30 October 2018

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1061575

30 October 2018

Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural requirements for the cytotoxicity of the N-terminal region of HIV type 1 Nef

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of the apoptosis-associated protein Grb3-3 in HIV-1-infected human CD4(+) lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 Nef protein prolonged recipient survival in rat liver allografting

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuropathogenesis of HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of mice deficient in interleukin-1 beta converting enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nef modulation of HIV type 1 gene expression and cytopathicity in tissues of HIV transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of HIV-1 nef in yeast: the 27 kDa Nef protein is myristylated and fractionates with the nucleus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P53: a determinant of the cell cycle response to DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal fluid p24 antigen levels and intrathecal immunoglobulin G synthesis are associated with cognitive disease severity in HIV-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 Nef-Induced Upregulation of DC-SIGN in Dendritic Cells Promotes Lymphocyte Clustering and Viral Spread

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and characterization of an interleukin-1beta-converting enzyme family protease that activates cysteine protease P32 (CPP32)

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurological complications of HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: identification by the combination of in situ polymerase chain reaction and immunohistochemistry

1 reference

https://pubmed.ncbi.nlm.nih.gov/15767427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.79.7.4257-4269.2005

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

ResearchGate publication ID

0 references

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