(Q33714237)

28 July 2017

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title

Pharmacokinetics of opioids in liver disease (English)

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28 July 2017

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1

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28 July 2017

Lötsch J

2

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PubMed ID

10451781

28 July 2017

Geisslinger G

series ordinal

3

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28 July 2017

1 July 1999

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Clinical Pharmacokinetics

28 July 2017

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28 July 2017

37

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28 July 2017

1

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28 July 2017

17-40

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https://scigraph.springernature.com/pub.10.2165/00003088-199937010-00002

28 July 2017

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cites work

Comparative pharmacokinetics of fentanyl and alfentanil.

1 reference

12 December 2020

Disposition of methadone in methadone maintenance

1 reference

12 December 2020

Morphine-6-O-beta-D-glucuronide but not morphine-3-O-beta-D-glucuronide binds to mu-, delta- and kappa- specific opioid binding sites in cerebral membranes

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of remifentanil in volunteer subjects with severe liver disease.

1 reference

12 December 2020

Interindividual and interethnic differences in the demethylation and glucuronidation of codeine

1 reference

12 December 2020

Presystemic glucuronidation of morphine in humans and rhesus monkeys: subcellular distribution of the UDP-glucuronyltransferase in the liver and intestine

1 reference

12 December 2020

UDP-glucuronyltransferase in perfused rat liver and in microsomes - III. Effects of galactosamine and carbon tetrachloride on the glucuronidation of 1-naphthol and bilirubin

1 reference

12 December 2020

Long lasting respiratory depression induced by morphine-6-glucuronide?

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of remifentanil in persons with renal failure compared with healthy volunteers.

1 reference

12 December 2020

Effects of liver disease on urinary excretion of methadone and metabolites in maintenance patients: quantitation by direct probe chemical ionization mass spectrometry

1 reference

12 December 2020

Effects of age on plasma protein binding of sufentanil.

1 reference

12 December 2020

Morphine-3-glucuronide may functionally antagonize morphine-6-glucuronide induced antinociception and ventilatory depression in the rat

1 reference

12 December 2020

Tricyclic antidepressants inhibit opioid receptor binding in human brain and hepatic morphine glucuronidation

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12 December 2020

Pharmacokinetics, efficacy, and safety of analgesia with a focus on tramadol HCl.

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12 December 2020

Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic

1 reference

12 December 2020

Fentanyl pharmacokinetics in anaesthetized patients with cirrhosis.

1 reference

12 December 2020

Sufentanil pharmacokinetics in patients with cirrhosis.

1 reference

12 December 2020

The Pharmacokinetics of Sufentanil in Surgical Patients

1 reference

12 December 2020

High-dose morphine and methadone in cancer patients. Clinical pharmacokinetic considerations of oral treatment

1 reference

12 December 2020

d-Methadone is antinociceptive in the rat formalin test

1 reference

12 December 2020

Properties of mu 3 opiate alkaloid receptors in macrophages, astrocytes, and HL-60 human promyelocytic leukemia cells.

1 reference

12 December 2020

Hepatic enzyme activity is the major factor determining elimination rate of high-clearance drugs in cirrhosis

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12 December 2020

Systemic availability of orally administered meperidine

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12 December 2020

Potency ratios of morphine and morphine-6beta-glucuronide analgesia elicited from the periaqueductal gray, locus coeruleus or rostral ventromedial medulla of rats.

1 reference

12 December 2020

Pharmacokinetics of tramadol and bioavailability of enteral tramadol formulations. 2nd communication: drops with ethanol.

1 reference

12 December 2020

Sufentanil Citrate: A New Opioid Analgesic for Use in Anesthesia

1 reference

12 December 2020

Postoperative course after sufentanil or fentanyl anesthesia for coronary artery surgery

1 reference

12 December 2020

Dihydrocodeine: a new opioid substrate for the polymorphic CYP2D6 in humans

1 reference

12 December 2020

Tramadol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in acute and chronic pain states

1 reference

12 December 2020

The influence of smoking on the intersubject variation in pentazocine elimination

1 reference

12 December 2020

Morphine-3-glucuronide has a minor effect on morphine antinociception. Pharmacodynamic modeling.

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12 December 2020

Pharmacokinetic and pharmacodynamic modeling in vivo

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12 December 2020

Biotransformation of tramadol in man and animal (author's transl)

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12 December 2020

Impaired elimination of meperidine in patients with liver disease

1 reference

12 December 2020

Preliminary pharmacokinetics and pharmacodynamics of an ultra-short-acting opioid: remifentanil (GI87084B).

1 reference

12 December 2020

Pharmacokinetics of high-dose meperidine in surgical patients

1 reference

12 December 2020

Pharmacokinetics of fentanyl in the elderly

1 reference

12 December 2020

Dextropropoxyphene kinetics after single and repeated oral doses in man.

1 reference

12 December 2020

Pharmacokinetics of sufentanil in neurosurgical patients undergoing hyperventilation.

1 reference

12 December 2020

Clinical pharmacokinetics of morphine

1 reference

12 December 2020

Cardio-Respiratory Toxicity of Propoxyphene and Norpropoxyphene in Conscious Rabbits*

1 reference

12 December 2020

Structure and function of uridine diphosphate glucuronosyltransferases

1 reference

12 December 2020

Pharmacokinetics of continuous infusion fentanyl in newborns.

1 reference

12 December 2020

The Clinical Pharmacology of Meperidine—Comparison of Routes of Administration

1 reference

12 December 2020

Normorphine, a neurotoxic metabolite?

1 reference

12 December 2020

Pharmacokinetics and effects on intracranial pressure of sufentanil in head trauma patients

1 reference

12 December 2020

Propoxyphene-induced wide QRS complex dysrhythmia responsive to sodium bicarbonate--a case report

1 reference

12 December 2020

Pharmacokinetics of tilidine and metabolites in man

1 reference

12 December 2020

Plasma morphine and morphine-6-glucuronide during chronic morphine therapy for cancer pain: plasma profiles, steady-state concentrations and the consequences of renal failure

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12 December 2020

Lack of morphine-6-glucuronide antinociception after morphine treatment. Is morphine-3-glucuronide involved?

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12 December 2020

Pharmacokinetics of sufentanil in obese patients

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12 December 2020

Pharmacokinetics of dextropropoxyphene and nordextropropoxyphene in elderly hospital patients after single and multiple doses of distalgesic. Preliminary analysis of results

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12 December 2020

Intrathecal morphine-3-glucuronide does not antagonize spinal antinociception by morphine or morphine-6-glucuronide in rats.

1 reference

12 December 2020

Context-sensitive half-time in multicompartment pharmacokinetic models for intravenous anesthetic drugs

1 reference

12 December 2020

Pharmacokinetics of high-dose fentanyl. A study in patients undergoing cardiac surgery.

1 reference

12 December 2020

Hepatic extraction of morphine is impaired in cirrhosis

1 reference

12 December 2020

Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite.

1 reference

12 December 2020

Human pharmacokinetics of intravenous, sublingual, and buccal buprenorphine

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12 December 2020

Lack of Analgesic Activity of Morphine-6-glucuronide after Short-term Intravenous Administration in Healthy Volunteers

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12 December 2020

Effect of GF120918, a potent P-glycoprotein inhibitor, on morphine pharmacokinetics and pharmacodynamics in the rat

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12 December 2020

Sufentanil disposition in patients undergoing renal transplantation: influence of choice of kinetic model.

1 reference

12 December 2020

Disposition and analgesic effects of systemic morphine, morphine-6-glucuronide and normorphine in rat.

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12 December 2020

Codeine increases pain thresholds to copper vapor laser stimuli in extensive but not poor metabolizers of sparteine.

1 reference

12 December 2020

Human pharmacokinetic study of immediate-release (codeine phosphate) and sustained-release (codeine Contin) codeine

1 reference

12 December 2020

Methadone in man: Pharmacokinetic and excretion studies in acute and chronic treatment

1 reference

12 December 2020

Alfentanil infusions in patients requiring intensive care

1 reference

12 December 2020

EEG quantitation of narcotic effect: the comparative pharmacodynamics of fentanyl and alfentanil

1 reference

12 December 2020

Central nervous system toxicity associated with meperidine use in hepatic disease

1 reference

12 December 2020

Evidence for P-glycoprotein-modulated penetration of morphine-6-glucuronide into brain capillary endothelium

1 reference

12 December 2020

Comparison of infusions of alfentanil or pethidine for sedation of ventilated patients on the ITU.

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of methadone in patients with chronic pain

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12 December 2020

Effects of morphine-3-glucuronide on the antinociceptive activity of peptide and nonpeptide opioid receptor agonists in mice

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12 December 2020

The metabolism and bioavailability of morphine in patients with severe liver cirrhosis

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12 December 2020

Morphine-3-glucuronide: evidence to support its putative role in the development of tolerance to the antinociceptive effects of morphine in the rat

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12 December 2020

Controlled-release oral morphine sulfate in the treatment of cancer pain with pharmacokinetic correlation

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12 December 2020

The analgesic activity of morphine-6-glucuronide

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12 December 2020

Influence of age and gender on the pharmacokinetics and pharmacodynamics of remifentanil. I. Model development.

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12 December 2020

Remifentanil versus alfentanil: comparative pharmacokinetics and pharmacodynamics in healthy adult male volunteers

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12 December 2020

Effects of aging and liver disease on disposition of lorazepam

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12 December 2020

Concentrations of morphine, morphine-6-glucuronide and morphine-3-glucuronide in serum and cerebrospinal fluid following morphine administration to patients with morphine-resistant pain.

1 reference

12 December 2020

Complementary and synergistic antinociceptive interaction between the enantiomers of tramadol

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12 December 2020

Pharmacokinetics of morphine-6-glucuronide and its formation from morphine after intravenous administration

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12 December 2020

d-Propoxyphene kinetics after single oral and intravenous doses in man

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12 December 2020

Evaluation of the methadone-alcohol interaction. I. Alterations of plasma concentration kinetics

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12 December 2020

Pharmacokinetics of single-dose i.v. morphine in normal volunteers and patients with end-stage renal failure

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12 December 2020

Tissue redistribution of fentanyl and termination of its effects in rats.

1 reference

12 December 2020

Differential alterations of cytochrome P450 proteins in livers from patients with severe chronic liver disease

1 reference

12 December 2020

Meperidine disposition in man: Influence of urinary pH and route of administration

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12 December 2020

Identification and quantitative determination of fentanyl metabolites in patients by gas chromatography--mass spectrometry.

1 reference

12 December 2020

Different effects of inhibitors on the O- and N-demethylation of codeine in human liver microsomes

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12 December 2020

Oral administration of codeine in the presence of ethanol: a pharmacokinetic study in man

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12 December 2020

Morphine pharmacokinetics and metabolism in humans. Enterohepatic cycling and relative contribution of metabolites to active opioid concentrations

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12 December 2020

The pharmacokinetics of morphine and morphine glucuronides in kidney failure

1 reference

12 December 2020

Protein binding of the analgesics alfentanil and sufentanil in maternal and neonatal plasma

1 reference

12 December 2020

Meperidine kinetics in man; Intravenous injection in surgical patients and volunteers

1 reference

12 December 2020

Kinetics of morphine in patients with renal failure

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12 December 2020

The metabolism and excretion of buprenorphine in humans

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12 December 2020

Morphine-3-glucuronide: silent regulator of morphine actions.

1 reference

12 December 2020

Modification by preoperative betablockade of the renin response to infrarenal aortic cross-clamping

1 reference

12 December 2020

Alfentanil pharmacokinetics in cardiac surgical patients.

1 reference

12 December 2020

Patient-controlled analgesia (PCA) with codeine for postoperative pain relief in ten extensive metabolisers and one poor metaboliser of dextromethorphan

1 reference

12 December 2020

Age and fentanyl pharmacokinetics.

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12 December 2020

Buprenorphine kinetics

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12 December 2020

Disposition and metabolism of codeine after single and chronic doses in one poor and seven extensive metabolisers

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12 December 2020

Stereoselective disposition of methadone in man.

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12 December 2020

Sublingual buprenorphine used postoperatively: ten hour plasma drug concentration analysis

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12 December 2020

Bioavailability of sublingual buprenorphine

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12 December 2020

Effect of severe alcoholic liver disease on the disposition of methadone in maintenance patients

1 reference

12 December 2020

Clinical pharmacokinetics of methadone

1 reference

12 December 2020

Variability of fentanyl pharmacokinetics in man. Computer predicted plasma concentrations for three intravenous dosage regimens.

1 reference

12 December 2020

Dextropropoxyphene induced hepatotoxicity: a report of nine cases

1 reference

12 December 2020

Morphine metabolism in man

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12 December 2020

Enhanced bioavailability and decreased clearance of analgesics in patients with cirrhosis

1 reference

12 December 2020

The pharmacokinetics of alfentanil in children.

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12 December 2020

Morphine-3-glucuronide--a potent antagonist of morphine analgesia

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12 December 2020

Morphine and phenytoin binding to plasma proteins in renal and hepatic failure

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12 December 2020

Pharmacokinetics of unchanged morphine in normal and cirrhotic subjects.

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12 December 2020

Enhanced bioavailability of pethidine and pentazocine in patients with cirrhosis of the liver

1 reference

12 December 2020

Release of latent glucuronosyltransferase activity contributes to the sparing of glucuronidation in experimental liver injuries

1 reference

12 December 2020

Marked QRS complex abnormalities and sodium channel blockade by propoxyphene reversed with lidocaine

1 reference

12 December 2020

Conjugation pathways in liver disease

1 reference

12 December 2020

Pharmacology of tramadol

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12 December 2020

Bioavailability of enteral tramadol formulations. 1st communication: capsules

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12 December 2020

Morphine 6-glucuronide and morphine 3-glucuronide as molecular chameleons with unexpected lipophilicity.

1 reference

12 December 2020

Pharmacokinetics of fentanyl in patients undergoing abdominal aortic surgery.

1 reference

12 December 2020

Hepatic encephalopathy

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12 December 2020

Both phenolic and acyl glucuronidation pathways of diflunisal are impaired in liver cirrhosis

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12 December 2020

Morphine and morphine metabolite concentrations in cerebrospinal fluid and plasma in cancer pain patients after slow-release oral morphine administration

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12 December 2020

Effects of age on meperidine disposition.

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12 December 2020

Linearity of pharmacokinetics and model estimation of sufentanil.

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12 December 2020

The relationship of pharmacokinetics to pharmacological activity: morphine, methadone and naloxone

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12 December 2020

Clinical pharmacokinetics of the newer intravenous anaesthetic agents

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12 December 2020

Morphine and metabolite behavior after different routes of morphine administration: demonstration of the importance of the active metabolite morphine-6-glucuronide

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12 December 2020

Murine macrophage cell lines contain mu 3-opiate receptors

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12 December 2020

Explanation for potency of repeated oral doses of morphine?

1 reference

12 December 2020

The effect of choline deficiency on the activity of a phosphatidylcholine-requiring enzyme: activity and properties of UDP-glucuronyltransferase in choline-deficient rats

1 reference

12 December 2020

Pharmacokinetics of intravenous and oral dihydrocodeine and its acid metabolites

1 reference

12 December 2020

Propoxyphene and norpropoxyphene plasma concentrations after oral propoxyphene in cirrhotic patients with and without surgically constructed portacaval shunt

1 reference

12 December 2020

Single dose pharmacokinetics and bioavailability of methadone in man studied with a stable isotope method

1 reference

12 December 2020

Alfentanil pharmacokinetics and metabolism in humans.

1 reference

12 December 2020

Poor permeability of morphine 3-glucuronide and morphine 6-glucuronide through the blood-brain barrier in the rat

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12 December 2020

Pharmacokinetics and pharmacodynamics of pentazocine in children.

1 reference

12 December 2020

Involvement of cytochrome P450 3A4 in N-dealkylation of buprenorphine in human liver microsomes

1 reference

12 December 2020

Plasma Protein Binding ofd-Propoxyphene in Normal Subjects and Anephric Patients

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12 December 2020

Propoxyphene overdose in Chinese subjects

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12 December 2020

Effect of chrysene and carbon tetrachloride administration on rat hepatic microsomal monooxygenase and UDPglucuronosyltransferase activity

1 reference

12 December 2020

The bioavailability and pharmacokinetics of morphine after intravenous, oral and buccal administration in healthy volunteers

1 reference

12 December 2020

Accumulation of normeperidine, an active metabolite of meperidine, in patients with renal failure of cancer

1 reference

12 December 2020

Comparative pharmacokinetics and pharmacodynamics of remifentanil, its principle metabolite (GR90291) and alfentanil in dogs

1 reference

12 December 2020

D-propoxyphene and norpropoxyphene kinetics after the oral administration of D-propoxyphene: a new approach to liver function?

1 reference

12 December 2020

A double blind comparison of high doses fentanyl and sufentanil in men. Influence on cardiovascular, respiratory and metabolic parameters

1 reference

12 December 2020

Pharmacokinetics, Pharmacodynamics, and Rational Opioid Selection

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12 December 2020

Propoxyphene and norpropoxyphene kinetics after single and repeated doses of propoxyphene

1 reference

12 December 2020

[Hepatotoxicity caused by dextropropoxyphene. Two cases, one of them with recurrence]

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12 December 2020

Subcutaneous fentanyl and sufentanil infusion substitution for morphine intolerance in cancer pain management

1 reference

12 December 2020

The effects of age and chronic liver disease on the elimination of temazepam

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12 December 2020

Single-dose kinetics and bioavailability of pentazocine

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12 December 2020

The visceral and somatic antinociceptive effects of dihydrocodeine and its metabolite, dihydromorphine. A cross-over study with extensive and quinidine-induced poor metabolizers

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12 December 2020

Biliary secretion of methadone and methadone metabolites in man.

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12 December 2020

Meperidine binding to isolated alpha 1-acid glycoprotein and albumin

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12 December 2020

The effect of cirrhosis on the disposition and elimination of meperidine in man

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12 December 2020

The Pharmacokinetics of Alfentanil (R39209): A New Opioid Analgesic

1 reference

12 December 2020

Opioid receptor activity of GI 87084B, a novel ultra-short acting analgesic, in isolated tissues

1 reference

12 December 2020

Impact of environmental and genetic factors on codeine analgesia

1 reference

12 December 2020

Pharmacodynamics and Pharmacokinetics of Methadone during the Perioperative Period

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12 December 2020

Presystemic metabolism of meperidine to normeperidine in normal and cirrhotic subjects

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12 December 2020

The effects of age and liver disease on the disposition and elimination of diazepam in adult man

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12 December 2020

The hypoalgesic effect of tramadol in relation to CYP2D6*

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12 December 2020

Disposition of morphine-6-glucuronide and morphine in healthy volunteers

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12 December 2020

Normal metabolism of morphine in cirrhosis

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12 December 2020

Dose comparison of remifentanil and alfentanil for loss of consciousness

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12 December 2020

Dose-independent pharmacokinetics of fentanyl.

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12 December 2020

Pharmacokinetics of morphine and its glucuronides after intravenous infusion of morphine and morphine-6-glucuronide in healthy volunteers*

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12 December 2020

Effect of age and parenchymal liver disease on the disposition and elimination of chlordiazepoxide (librium).

1 reference

12 December 2020

Pharmacokinetics of methadone during maintenance therapy: Pulse labeling with deuterated methadone in the steady state

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12 December 2020

Hepatotoxicity of dextropropoxyphene

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12 December 2020

Modulation of morphine-6-glucuronide penetration into the brain by P-glycoprotein.

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12 December 2020

Morphine-6-glucuronide, a potent mu agonist.

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12 December 2020

Codeine disposition in smokers and nonsmokers

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12 December 2020

Plasma and cerebrospinal fluid concentrations of morphine and morphine glucuronides after oral morphine. The influence of renal failure.

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12 December 2020

Alcoholic liver disease: information in search of knowledge?

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12 December 2020

The influence of hepatic plasma flow on alfentanil plasma concentration plateaus achieved with an infusion model in humans: measurement of alfentanil hepatic extraction coefficient.

1 reference

12 December 2020

Analgesia by dihydrocodeine is not due to formation of dihydromorphine: evidence from nociceptive activity in rat thalamus.

1 reference

12 December 2020

Comparative analysis of buprenorphine- and norbuprenorphine-induced analgesic effects based on pharmacokinetic-pharmacodynamic modeling

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12 December 2020

Involvement of cytochrome P450 3A4 enzyme in the N-demethylation of methadone in human liver microsomes

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12 December 2020

Mechanism for reduced drug clearance in patients with cirrhosis

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12 December 2020

Interaction of methadone and ethanol metabolism.

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12 December 2020

Role of opioidergic and serotonergic mechanisms in cough and antitussives

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12 December 2020

Effects of liver disease on fecal excretion of methadone and its unconjugated metabolites in maintenance patients. Quantitation by direct probe chemical ionization mass spectrometry

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12 December 2020

Respiratory depression following morphine and morphine-6-glucuronide in normal subjects.

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12 December 2020

Concentrations of morphine and morphine metabolites in CSF and plasma during continuous subcutaneous morphine administration in cancer pain patients.

1 reference

12 December 2020

Liver blood flow. I. Intrinsic and nervous control of liver blood flow.

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12 December 2020

An evaluation of the effects of smoking on codeine pharmacokinetics and bioavailability in normal human volunteers

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12 December 2020

Clinical pharmacokinetics of fentanyl and its newer derivatives.

1 reference

12 December 2020

Pharmacokinetics of continuous infusions of fentanyl in critically ill children.

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12 December 2020

Plasma concentrations of fentanyl with subcutaneous infusion in palliative care patients

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12 December 2020

Extrahepatic metabolism of morphine occurs in humans

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12 December 2020

Codeine and morphine in extensive and poor metabolizers of sparteine: pharmacokinetics, analgesic effect and side effects

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12 December 2020

Effect of prior morphine-3-glucuronide exposure on morphine disposition and antinociception

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12 December 2020

Human metabolism of orally administered pentazocine

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12 December 2020

Codeine kinetics as determined by radioimmunoassay

1 reference

12 December 2020

The influence of pharmacogenetics on opioid analgesia: studies with codeine and oxycodone in the Sprague-Dawley/Dark Agouti rat model

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12 December 2020

Alfentanil infusions on the intensive therapy unit.

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12 December 2020

Opioid pharmacokinetics in relation to their effects

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12 December 2020

Selective effect of liver disease on the activities of specific metabolizing enzymes: investigation of cytochromes P450 2C19 and 2D6.

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12 December 2020

Plasma concentrations of morphine, morphine-3-glucuronide, and morphine-6-glucuronide after intravenous and oral administration to healthy volunteers: relationship to nonanalgesic actions

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12 December 2020

Morphine tolerance in hepatic cirrhosis

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12 December 2020

Dextropropoxyphene induced hepatotoxicity mimicking biliary tract disease

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12 December 2020

The apparent affinity of morphine-3-glucuronide at mu1-opioid receptors results from morphine contamination: demonstration using HPLC and radioligand binding

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12 December 2020

Determinants of drug disposition in patients with cirrhosis.

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12 December 2020

Contribution of the human kidney to the metabolic clearance of drugs

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12 December 2020

Morphine-6-glucuronide concentrations and opioid-related side effects: a survey in cancer patients

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12 December 2020

Effect of cardiopulmonary bypass on fentanyl distribution and elimination.

1 reference

12 December 2020

Uptake, 3-, and 6-glucuronidation of morphine in isolated cells from stomach, intestine, colon, and liver of the guinea pig.

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12 December 2020

Opioid Agonist-Antagonist Drugs in Acute and Chronic Pain States

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12 December 2020

The Metabolism of Morphine and Heroin in Man

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12 December 2020

Intravenous fentanyl kinetics.

1 reference

12 December 2020

UDP glucuronosyltransferase in the cirrhotic rat liver

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12 December 2020

Clinical pharmacokinetics of alfentanyl (author's transl)

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12 December 2020

The pharmacokinetics of the new short-acting opioid remifentanil (GI87084B) in healthy adult male volunteers

1 reference

12 December 2020

On the metabolism of ethyl-DL-trans-2-dimethylamino-1-phenyl-cyclohex-3-ene-trans-1-carboxylate-hydrochloride (Tilidine-HCl). 2nd Communication: Studies with 14C-labelled substance on rats and dogs

1 reference

12 December 2020

Pre-translational regulation of cytochrome P450 genes is responsible for disease-specific changes of individual P450 enzymes among patients with cirrhosis.

1 reference

12 December 2020

Receptor binding, analgesic and antitussive potency of tramadol and other selected opioids

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12 December 2020

Electroencephalographic quantitation of opioid effect: comparative pharmacodynamics of fentanyl and sufentanil

1 reference

12 December 2020

Buprenorphine: a review of its pharmacological properties and therapeutic efficacy

1 reference

12 December 2020

Measured context-sensitive half-times of remifentanil and alfentanil.

1 reference

12 December 2020

Continuous infusions of fentanyl and alfentanil in intensive care (abstract).

1 reference

12 December 2020

Effects of different hepatic pathologies on disposition of alfentanil in anaesthetized patients.

1 reference

12 December 2020

Serum protein binding of fentanyl. The effect of postoperative acute phase reaction with elevated alpha 1-acid glycoprotein and methodologic problems in determination by equilibrium dialysis

1 reference

12 December 2020

Plasma protein binding and distribution of fentanyl, sufentanil, alfentanil and lofentanil in blood

1 reference

12 December 2020

Enterohepatic circulation of morphine

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12 December 2020

Buprenorphine disposition in patients with renal impairment: single and continuous dosing, with special reference to metabolites

1 reference

12 December 2020

Analgesic efficacy and CSF pharmacokinetics of intrathecal morphine-6-glucuronide: comparison with morphine

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12 December 2020

Plasma and tissue protein binding of drugs in pharmacokinetics

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12 December 2020

Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation

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12 December 2020

Renal glucuronidation of morphine in the human foetus

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12 December 2020

Sufentanil pharmacokinetics in pediatric cardiovascular patients.

1 reference

12 December 2020

Single-dose and steady-state kinetics of morphine and its metabolites in cancer patients--a comparison of two oral formulations

1 reference

12 December 2020

Morphine formation from codeine in rat brain: a possible mechanism of codeine analgesia.

1 reference

12 December 2020

Methadone disposition in patients with chronic liver disease

1 reference

12 December 2020

Human buprenorphine N-dealkylation is catalyzed by cytochrome P450 3A4.

1 reference

12 December 2020

Pharmacokinetics of alfentanil in man

1 reference

12 December 2020

The role of cytochrome P450 3A4 in alfentanil clearance. Implications for interindividual variability in disposition and perioperative drug interactions.

1 reference

12 December 2020

Pharmacokinetics of remifentanil (GI87084B) and its major metabolite (GI90291) in patients undergoing elective inpatient surgery.

1 reference

12 December 2020

Alfentanil pharmacokinetics in patients with cirrhosis.

1 reference

12 December 2020

Pharmacokinetics of methadone during maintenance treatment: adaptive changes during the induction phase

1 reference

12 December 2020

Pharmacokinetics of sufentanil in general surgical patients under different conditions of anaesthesia.

1 reference

12 December 2020

Lack of effect of morphine-3-glucuronide on the spinal antinociceptive actions of morphine in the rat: an electrophysiological study.

1 reference

12 December 2020

Kinetics of intravenous and intramuscular morphine

1 reference

12 December 2020

Bioavailability and first-pass metabolism of oral pentazocine in man

1 reference

12 December 2020

The role of membrane lipids in the regulation of membrane-bound enzymes

1 reference

12 December 2020

Normal disposition of oxazepam in acute viral hepatitis and cirrhosis

1 reference

12 December 2020

Pharmacologie du tramadol

1 reference

12 December 2020

10.2165/00003088-199937010-00002

Identifiers

DOI

1 reference

PubMed ID

10451781

Dimensions Publication ID

28 July 2017

0 references

1 reference

PubMed ID

10451781