(Q33715954)

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The type of Aβ-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid β-peptide (APP48) transgenic mice

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1 March 2020

The type of Aβ-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid β-peptide (APP48) transgenic mice (English)

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1 March 2020

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1 March 2020

Dietmar R. Thal

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1 March 2020

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Ajeet Rijal Upadhaya

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1 March 2020

Frederik Scheibe

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1 March 2020

Irina Kosterin

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1 March 2020

Dorothee Abramowski

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1 March 2020

Janina Gerth

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1 March 2020

Stefan Liebau

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1 March 2020

Haruyasu Yamaguchi

8

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1 March 2020

Jochen Walter

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1 March 2020

Matthias Staufenbiel

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1 March 2020

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18 November 2013

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1 March 2020

Acta Neuropathologica Communications

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1 March 2020

1

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1 March 2020

77

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1 March 2020

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0 references

Drain of the brain: low-affinity p75 neurotrophin receptor affords a molecular sink for clearance of cortical amyloid β by the cholinergic modulator system

1 reference

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21 June 2018

Neurotrophin receptor p75 mediates the uptake of the amyloid beta (Aβ) peptide, guiding it to lysosomes for degradation in basal forebrain cholinergic neurons.

1 reference

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21 June 2018

Amyloid β precursor protein as a molecular target for amyloid β--induced neuronal degeneration in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Membrane trafficking pathways in Alzheimer's disease

1 reference

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21 June 2018

Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Effects of synaptic modulation on beta-amyloid, synaptophysin, and memory performance in Alzheimer's disease transgenic mice.

1 reference

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21 June 2018

Morphological and functional abnormalities in mitochondria associated with synaptic degeneration in prion disease.

1 reference

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21 June 2018

The presence of sodium dodecyl sulphate-stable Abeta dimers is strongly associated with Alzheimer-type dementia.

1 reference

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21 June 2018

ER stress-mediated apoptotic pathway induced by Abeta peptide requires the presence of functional mitochondria.

1 reference

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21 June 2018

Overexpression of tau proteins antagonizes amyloid-beta-potentiated apoptosis through mitochondria-caspase-3 pathway in N2a cells

1 reference

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21 June 2018

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

1 reference

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21 June 2018

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Amyloid-beta E22Delta variant induces synaptic alteration in mouse hippocampal slices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Internalized antibodies to the Abeta domain of APP reduce neuronal Abeta and protect against synaptic alterations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Selective vulnerability of different types of commissural neurons for amyloid beta-protein-induced neurodegeneration in APP23 mice correlates with dendritic tree morphology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Alzheimer's disease beta-amyloid peptides are released in association with exosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Occurrence and co-localization of amyloid beta-protein and apolipoprotein E in perivascular drainage channels of wild-type and APP-transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy

1 reference

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21 June 2018

Abeta42 is essential for parenchymal and vascular amyloid deposition in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

1 reference

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21 June 2018

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

1 reference

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21 June 2018

Pathogenic mechanisms of Alzheimer's disease analyzed in the APP23 transgenic mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Intraneuronal Abeta42 accumulation in human brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Estimation of the number of synapses in the cerebral cortex: methodological considerations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Diffuse plaques associated with astroglial amyloid beta protein, possibly showing a disappearing stage of senile plaques.

1 reference

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21 June 2018

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

The pathogenesis of senile plaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Stereological principles for morphometry in electron microscopic cytology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Synaptic patterns on different cell types in the different laminae of the cat visual cortex. An electron microscope study

1 reference

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21 June 2018

Amyloid plaque core protein in Alzheimer disease and Down syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease

1 reference

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21 June 2018

Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

21 June 2018

Some morphometric aspects of the brain in senile dementia of the alzheimer type

1 reference

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21 January 2018

Consistent immunohistochemical detection of intracellular beta-amyloid42 in pyramidal neurons of Alzheimer's disease entorhinal cortex

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo.

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice.

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

Intraneuronal amyloid β oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo.

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

Transgenic expression of intraneuronal Aβ42 but not Aβ40 leads to cellular Aβ lesions, degeneration, and functional impairment without typical Alzheimer's disease pathology.

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

Dispersible amyloid β-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (APP) transgenic mice.

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques.

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

Early intraneuronal accumulation and increased aggregation of phosphorylated Abeta in a mouse model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach.

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

Reorganization of inhibitory synapses and increased PSD length of perforated excitatory synapses in hippocampal area CA1 of dystrophin-deficient mdx mice.

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

Neprilysin-sensitive synapse-associated amyloid-beta peptide oligomers impair neuronal plasticity and cognitive function.

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches.

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

A new amyloid beta variant favoring oligomerization in Alzheimer's-type dementia.

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

Mitochondrial amyloid-beta levels are associated with the extent of mitochondrial dysfunction in different brain regions and the degree of cognitive impairment in Alzheimer's transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

30 October 2018

Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

30 October 2018

Qualitative and quantitative differences in senile plaque dystrophic neurites of Alzheimer's disease and normal aged brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4046770

30 October 2018

Neuron loss in APP transgenic mice

1 reference

https://api.crossref.org/works/10.1186%2F2051-5960-1-77

21 January 2018

Interhemispheric asymmetries of the modular structure in human temporal cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/24252227

12 December 2020

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inferred from PubMed ID database lookup

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10.1186/2051-5960-1-77

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1 March 2020

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24252227%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

Europe PubMed Central

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1 March 2020

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