(Q33828482)

29 July 2017

title

An angiotensin II type 1 receptor activation switch patch revealed through evolutionary trace analysis (English)

1 reference

29 July 2017

5

Stig Haunsø

1 reference

29 July 2017

10

Jakob Lerche Hansen

0 references

Olivier Lichtarge

9

object named as

Olivier Lichtarge

1 reference

29 July 2017

Marie Mi Bonde

1

1 reference

29 July 2017

Rong Yao

2

1 reference

29 July 2017

Jian-Nong Ma

3

1 reference

29 July 2017

Srinivasan Madabushi

4

1 reference

29 July 2017

Ethan S Burstein

6

1 reference

29 July 2017

Jennifer L Whistler

7

1 reference

29 July 2017

Søren P Sheikh

8

1 reference

29 July 2017

Jakob Lerche Hansen

10

1 reference

29 July 2017

language of work or name

English

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publication date

21 March 2010

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29 July 2017

published in

Biochemical Pharmacology

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29 July 2017

volume

80

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29 July 2017

issue

1

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29 July 2017

page(s)

86-94

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Ligand binding and micro-switches in 7TM receptor structures

29 July 2017

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1 reference

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Molecular determinants of angiotensin II type 1 receptor functional selectivity

4 July 2018

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Crystal structure of opsin in its G-protein-interacting conformation

4 July 2018

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Structural motifs of importance for the constitutive activity of the orphan 7TM receptor EBI2: analysis of receptor activation in the absence of an agonist

4 July 2018

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GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

4 July 2018

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Clustal W and Clustal X version 2.0

4 July 2018

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Conformational complexity of G-protein-coupled receptors

4 July 2018

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Kinins promote B2 receptor endocytosis and delay constitutive B1 receptor endocytosis

4 July 2018

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4 July 2018

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beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor

4 July 2018

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Pleiotropic AT1 receptor signaling pathways mediating physiological and pathogenic actions of angiotensin II.

4 July 2018

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Single mutations at Asn295 and Leu305 in the cytoplasmic half of transmembrane alpha-helix domain 7 of the AT1 receptor induce promiscuous agonist specificity for angiotensin II fragments: a pseudo-constitutive activity

4 July 2018

1 reference

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Structure of bovine rhodopsin in a trigonal crystal form.

4 July 2018

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The Role of a Conserved Region of the Second Intracellular Loop in AT1 Angiotensin Receptor Activation and Signaling

4 July 2018

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Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors

4 July 2018

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Constitutive internalization of constitutively active agiotensin II AT(1A) receptor mutants is blocked by inverse agonists

4 July 2018

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Prediction and confirmation of a site critical for effector regulation of RGS domain activity

4 July 2018

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Systematic identification of mutations that constitutively activate the angiotensin II type 1A receptor by screening a randomly mutated cDNA library with an original pharmacological bioassay

4 July 2018

1 reference

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Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

4 July 2018

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A regulator of G protein signaling interaction surface linked to effector specificity

4 July 2018

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Mutation of a highly conserved aspartic acid in the beta2 adrenergic receptor: constitutive activation, structural instability, and conformational rearrangement of transmembrane segment 6.

4 July 2018

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C5a receptor activation. Genetic identification of critical residues in four transmembrane helices

4 July 2018

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Cellular trafficking of G protein-coupled receptor/beta-arrestin endocytic complexes

4 July 2018

1 reference

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The functional topography of transmembrane domain 3 of the M1 muscarinic acetylcholine receptor, revealed by scanning mutagenesis.

4 July 2018

1 reference

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Constitutive activity of glucagon receptor mutants

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864232

A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation

4 July 2018

1 reference

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Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864232

Functional interaction of transmembrane helices 3 and 6 in rhodopsin. Replacement of phenylalanine 261 by alanine causes reversion of phenotype of a glycine 121 replacement mutant.

4 July 2018

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Pharmacology of muscarinic acetylcholine receptor subtypes (m1-m5): high throughput assays in mammalian cells

4 July 2018

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An evolutionary trace method defines binding surfaces common to protein families

4 July 2018

1 reference

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A missense mutation in the second transmembrane segment of the luteinizing hormone receptor causes familial male-limited precocious puberty

4 July 2018

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Basic local alignment search tool

4 July 2018

1 reference

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The human angiotensin AT(1) receptor supports G protein-independent extracellular signal-regulated kinase 1/2 activation and cellular proliferation

4 July 2018

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29 October 2018

1 reference

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Loss-of-function polymorphic variants of the human angiotensin II type 1 receptor

29 October 2018

1 reference

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Evolutionary trace of G protein-coupled receptors reveals clusters of residues that determine global and class-specific functions

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2864232

Structural clusters of evolutionary trace residues are statistically significant and common in proteins

29 October 2018

1 reference

12 December 2020

An Accurate, Sensitive, and Scalable Method to Identify Functional Sites in Protein Structures

1 reference

12 December 2020

Constitutive activation of the human vasoactive intestinal peptide 1 receptor, a member of the new class II family of G protein-coupled receptors

1 reference

12 December 2020

Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions

1 reference

12 December 2020

Oxyntomodulin differentially affects glucagon-like peptide-1 receptor beta-arrestin recruitment and signaling through Galpha(s)

1 reference

12 December 2020

Angiotensin II AT1 receptor constitutive activation: from molecular mechanisms to pathophysiology

1 reference

12 December 2020

Extracellular signal-regulated kinases control expression of G protein-coupled receptor kinase 2 (GRK2)

1 reference

12 December 2020

10.1016/J.BCP.2010.03.006

Identifiers

DOI

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29 July 2017

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29 July 2017

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