(Q33905646)

29 July 2017

title

Multixenobiotic resistance as a cellular defense mechanism in aquatic organisms (English)

1 reference

29 July 2017

Bard SM

1

1 reference

29 July 2017

publication date

1 April 2000

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29 July 2017

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29 July 2017

volume

48

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29 July 2017

issue

4

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29 July 2017

page(s)

357-389

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The multidrug resistance (mdr1) gene product functions as an ATP channel

29 July 2017

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What have we learnt thus far from mice with disrupted P-glycoprotein genes?

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P-glycoprotein structure and evolutionary homologies

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7 January 2021

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A P-glycoprotein protects Caenorhabditis elegans against natural toxins

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7 January 2021

cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats

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7 January 2021

Coinduction of MDR-1 multidrug-resistance and cytochrome P-450 genes in rat liver by xenobiotics.

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7 January 2021

A homologue of the mammalian multidrug resistance gene (mdr) is functionally expressed in the intestine of Xenopus laevis

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7 January 2021

Immunochemical relationships of cytochrome P4503A-like proteins in teleost fish

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7 January 2021

Mechanisms regulating cell resistance to adriamycin. Evidence that drug accumulation in resistant cells is modulated by phosphorylation of a plasma membrane glycoprotein

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7 January 2021

Correlation of protein kinase C translocation, P-glycoprotein phosphorylation and reduced drug accumulation in multidrug resistant human KB cells

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7 January 2021

Multidrug-resistant human KB carcinoma cells are highly resistant to the protein phosphatase inhibitors okadaic acid and calyculin A. Analysis of potential mechanisms involved in toxin resistance.

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7 January 2021

P-glycoprotein genes in the winter flounder, Pleuronectes americanus: isolation of two types of genomic clones carrying 3' terminal exons

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7 January 2021

Induction of multidrug resistance in human cells by transient exposure to different chemotherapeutic drugs.

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7 January 2021

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

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7 January 2021

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

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7 January 2021

Altered expression of the xenobiotic transporter P-glycoprotein in liver and liver tumours of mummichog Fundulus heteroclitus from a creosote-contaminated environment

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Cloning and characterisation of a novel P-glycoprotein homologue from barley

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

The brown protein of Drosophila melanogaster is similar to the white protein and to components of active transport complexes

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7 January 2021

Cmdr1, a chicken P-glycoprotein, confers multidrug resistance and interacts with estradiol

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7 January 2021

The biochemistry of P-glycoprotein-mediated multidrug resistance

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7 January 2021

Mechanism of action of P-glycoprotein in relation to passive membrane permeation.

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https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

The role of passive transbilayer drug movement in multidrug resistance and its modulation

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https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Carcinogen-induced mdr overexpression is associated with xenobiotic resistance in rat preneoplastic liver nodules and hepatocellular carcinomas

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https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

P-glycoprotein induction in rat liver epithelial cells in response to acute 3-methylcholanthrene treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Up-regulation of P-glycoprotein expression in rat liver cells by acute doxorubicin treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Overexpression of the multidrug resistance gene product in adult rat hepatocytes during primary culture

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Expression of a multidrug-resistance gene in human tumors and tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum

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https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Regulation of 2-acetylaminofluorene-and 3-methylcholanthrene-mediated induction of multidrug resistance and cytochrome P450IA gene family expression in primary hepatocyte cultures and rat liver

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https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

In Vivo Induction of Liver P-Glycoprotein Expression by Xenobiotics in Monkeys

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7 January 2021

Regulation of P-glycoprotein gene expression in hepatocyte cultures and liver cell lines by a trans-acting transcriptional repressor

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7 January 2021

Absence of cooperativity for MgATP and verapamil effects on the ATPase activity of P-glycoprotein containing membrane vesicles

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7 January 2021

The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver

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https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Characterization of phosphorylation-defective mutants of human P-glycoprotein expressed in mammalian cells

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7 January 2021

Protein kinase C-mediated phosphorylation does not regulate drug transport by the human multidrug resistance P-glycoprotein

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7 January 2021

Immunohistochemical detection of P-glycoprotein in teleost tissues using mammalian polyclonal and monoclonal antibodies.

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7 January 2021

Complete in vivo reversal of P-glycoprotein pump function in the blood-brain barrier visualized with positron emission tomography

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7 January 2021

ABC Transporters: From Microorganisms to Man

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7 January 2021

P-glycoprotein and cell volume-activated chloride channels

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7 January 2021

Is the multidrug transporter a flippase?

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7 January 2021

1 reference

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7 January 2021

Overexpression of P-glycoprotein in mammalian tumor cell lines after fractionated X irradiation in vitro.

1 reference

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7 January 2021

The ATP-dependent glutathione S-conjugate export pump

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

ABC transporters in Archaea: two genes encoding homologs of the nucleotide-binding components in the methanogen Methanosarcina mazei S-6.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Quantitative structure-activity relationship of multidrug resistance reversal agents

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Comparison of archaeal and bacterial genomes: computer analysis of protein sequences predicts novel functions and suggests a chimeric origin for the archaea

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7 January 2021

Phase I/II trial of dexverapamil, epirubicin, and granulocyte-macrophage-colony stimulating factor in patients with advanced pancreatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

The multixenobiotic resistance mechanism in aquatic organisms

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Expression of P-glycoprotein gene in marine sponges. Identification and characterization of the 125 kDa drug-binding glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

P-glycoprotein deficiency in a subpopulation of CF-1 mice enhances avermectin-induced neurotoxicity

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7 January 2021

Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice

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7 January 2021

Tobacco budworm P-glycoprotein: biochemical characterization and its involvement in pesticide resistance

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7 January 2021

Multidrug resistance mediated by the multidrug resistance protein (MRP) gene.

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7 January 2021

Phase II trial of dexverapamil and epirubicin in patients with non-responsive metastatic breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

The P-glycoprotein gene family of Caenorhabditis elegans. Cloning and characterization of genomic and complementary DNA sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Site-directed fluorescence labeling of P-glycoprotein on cysteine residues in the nucleotide binding domains.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids

1 reference

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7 January 2021

Multiple pathways of organic anion secretion in renal proximal tubule revealed by confocal microscopy

1 reference

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7 January 2021

Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Gene amplification-associated cytogenetic aberrations and protein changes in vincristine-resistant Chinese hamster, mouse, and human cells

1 reference

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7 January 2021

Daunomycin secretion by killfish renal proximal tubules

1 reference

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7 January 2021

Excretory transport of xenobiotics by dogfish shark rectal gland tubules

1 reference

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7 January 2021

Protein kinase C regulation of p-glycoprotein-mediated xenobiotic secretion in renal proximal tubule

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Steroid hormones inhibit binding of Vinca alkaloid to multidrug resistance related P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Use of fluorescent dyes as molecular probes for the study of multidrug resistance

1 reference

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7 January 2021

Identification of members of the P-glycoprotein multigene family

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

P-glycoprotein as multidrug transporter: a critical review of current multidrug resistant cell lines

1 reference

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7 January 2021

Structural characteristics of compounds that modulate P-glycoprotein-associated multidrug resistance

1 reference

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7 January 2021

Unchanged cytochrome P450 3A (CYP3A) expression and metabolism of midazolam, triazolam, and dexamethasone in mdr(-/-) mouse liver microsomes.

1 reference

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7 January 2021

Detection of a P-glycoprotein related pump in Chironomus larvae and its inhibition by verapamil and cyclosporin A.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Polyaromatic alkaloids from marine invertebrates as cytotoxic compounds and inhibitors of multidrug resistance caused by P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Stability and covalent modification of P-glycoprotein in multidrug-resistant KB cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Chemical synthesis and biological properties of novel fluorescent antifolates in Pgp- and MRP-overexpressing tumour cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

A mechanism for P-glycoprotein action in multidrug resistance: are we there yet?

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Modulation of P-glycoprotein expression by cytochrome P450 3A inducers in male and female rat livers.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Getting in or out: early segregation between importers and exporters in the evolution of ATP-binding cassette (ABC) transporters

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

The drug resistance-related protein LRP is the human major vault protein

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https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

The physiological function of drug-transporting P-glycoproteins

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

P-glycoprotein-mediated secretion of a fluorescent cyclosporin analogue by teleost renal proximal tubules

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Metabolic activation of 2-acetylaminofluorene is required for induction of multidrug resistance gene expression in rat liver cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Induction of multidrug resistance gene expression during cholestasis in rats and nonhuman primates.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Inhibitory effects of extracts from the marine alga Caulerpa taxifolia and of toxin from Caulerpa racemosa on multixenobiotic resistance in the marine sponge Geodia cydonium

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Assessment of risk reduction strategies for the management of agricultural nonpoint source pesticide runoff in estuarine ecosystems

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

A general pattern for substrate recognition by P-glycoprotein.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Modulation of MDR1 and CYP3A expression by dexamethasone: evidence for an inverse regulation in adrenals

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Stimulation of P-glycoprotein-mediated drug transport by prazosin and progesterone. Evidence for a third drug-binding site.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Using purified P-glycoprotein to understand multidrug resistance.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

The P-glycoprotein efflux pump: how does it transport drugs?

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Human multidrug-resistant cell lines: increased mdr1 expression can precede gene amplification

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Involvement of an ABC transporter in a developmental pathway regulating hypocotyl cell elongation in the light

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

The rectal gland of Squalus acanthias: a model for the transport of chloride

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Hepatobiliary and intestinal clearance of amphiphilic cationic drugs in mice in which both mdr1a and mdr1b genes have been disrupted

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

The chemosensitizers of multixenobiotic resistance mechanism in aquatic invertebrates: a new class of pollutants

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Cellular resistance to cancer chemotherapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Multiple cytochrome P-450 subfamilies are co-induced with P-glycoprotein by both phenothiazine and 2-acetylaminofluorene in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Murine mdr-1, mdr-2, and mdr-3 gene expression: no coinduction with the Cyp1a-1 and Nmo-1 genes in liver by 2,3,7,8-tetrachlorodibenzo-p-dioxin

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Multixenobiotic Resistance in Urechis caupo Embryos: Protection From Environmental Toxins

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https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Sister of P-glycoprotein expression in different tissues

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https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Co-ordinate regulation of the cystic fibrosis and multidrug resistance genes in cystic fibrosis knockout mice

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https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Both P-glycoprotein Nucleotide-binding Sites Are Catalytically Active

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Sequence of mdr3 cDNA encoding a human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

P-glycoprotein: clinical significance and methods of analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Increased genotoxicity of acetylaminofluorene by modulators of multixenobiotic resistance mechanism: studies with the fresh water clam Corbicula fluminea

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

A potato cDNA encoding a homologue of mammalian multidrug resistant P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

The barrier function of CYP3A4 and P-glycoprotein in the small bowel

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

A marine natural product, patellamide D, reverses multidrug resistance in a human leukemic cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Cell-volume regulation: P-glycoprotein--a cautionary tale

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

P-glycoprotein transports corticosterone and is photoaffinity-labeled by the steroid

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

High-affinity maltose/trehalose transport system in the hyperthermophilic archaeon Thermococcus litoralis.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Reactive oxygen species participate in mdr1b mRNA and P-glycoprotein overexpression in primary rat hepatocyte cultures.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

Down-regulation of the mdr gene by thyroid hormone during Xenopus laevis development.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-445X%2800%2900088-6

7 January 2021

10.1016/S0166-445X(00)00088-6

Identifiers

DOI

1 reference

29 July 2017

1 reference