(Q33952766)

English

Methotrexate-induced side effects are not due to differences in pharmacokinetics in children with Down syndrome and acute lymphoblastic leukemia

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scholarly article

1 reference

Europe PubMed Central

30 July 2017

Methotrexate-induced side effects are not due to differences in pharmacokinetics in children with Down syndrome and acute lymphoblastic leukemia (English)

1 reference

Europe PubMed Central

30 July 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

lymphoblastic leukemia

1 reference

based on heuristic

inferred from title

4

object named as

Rob Pieters

1 reference

Europe PubMed Central

30 July 2017

author name string

Trudy D Buitenkamp

1

1 reference

Europe PubMed Central

30 July 2017

Ron A A Mathôt

2

1 reference

Europe PubMed Central

30 July 2017

Valerie de Haas

3

1 reference

Europe PubMed Central

30 July 2017

C Michel Zwaan

5

1 reference

Europe PubMed Central

30 July 2017

publication date

23 April 2010

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

95

1 reference

Europe PubMed Central

30 July 2017

7

1 reference

Europe PubMed Central

30 July 2017

1106-1113

1 reference

Europe PubMed Central

30 July 2017

Acute leukemias in children with Down syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

5 July 2018

Mechanism-based concepts of size and maturity in pharmacokinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

5 July 2018

Integrating molecular information into treatment of childhood acute lymphoblastic leukemia--a perspective from the BFM Study Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

5 July 2018

Ancestry and pharmacogenetics of antileukemic drug toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

5 July 2018

Acute lymphoblastic leukaemia: a model for the pharmacogenomics of cancer therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

5 July 2018

Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

5 July 2018

Down syndrome, drug metabolism and chromosome 21.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

5 July 2018

Down's syndrome and acute lymphoblastic leukaemia: clinical features and response to treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

5 July 2018

Classification of ex vivo methotrexate resistance in acute lymphoblastic and myeloid leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

5 July 2018

Risks of leukaemia and solid tumours in individuals with Down's syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

5 July 2018

Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

5 July 2018

Pharmacokinetics and toxicity of methotrexate in children with Down syndrome and acute lymphocytic leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

5 July 2018

Down syndrome and leukemia: unusual clinical aspects and unexpected methotrexate sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

5 July 2018

Methotrexate sensitivity in Down's syndrome: a hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

5 July 2018

Dexamethasone-based therapy for childhood acute lymphoblastic leukaemia: results of the prospective Dutch Childhood Oncology Group (DCOG) protocol ALL-9 (1997-2004).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

29 October 2018

Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

29 October 2018

Outcome and toxicity of chemotherapy for acute lymphoblastic leukemia in children with Down syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

29 October 2018

Polymorphisms in folate-related genes: association with side effects of high-dose methotrexate in childhood acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

29 October 2018

Prevalence, neonatal characteristics, and first-year mortality of Down syndrome: a national study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

29 October 2018

High-dose compared with intermediate-dose methotrexate in children with a first relapse of acute lymphoblastic leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

29 October 2018

Cytogenetic features of acute lymphoblastic and myeloid leukemias in pediatric patients with Down syndrome: an iBFM-SG study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

29 October 2018

A limited sampling strategy to estimate individual pharmacokinetic parameters of methotrexate in children with acute lymphoblastic leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

29 October 2018

Population pharmacokinetics of high-dose methotrexate in children with acute lymphoblastic leukaemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

29 October 2018

BFM-oriented treatment for children with acute lymphoblastic leukemia without cranial irradiation and treatment reduction for standard risk patients: results of DCLSG protocol ALL-8 (1991-1996).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

29 October 2018

Distinctive multidrug sensitivity and outcome of acute erythroblastic and megakaryoblastic leukemia in children with Down syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

29 October 2018

Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

29 October 2018

Role of folylpolyglutamate synthetase and folylpolyglutamate hydrolase in methotrexate accumulation and polyglutamylation in childhood leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

29 October 2018

Balanced designs in longitudinal population pharmacokinetic studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

29 October 2018

Down's syndrome in childhood acute lymphoblastic leukemia: clinical characteristics and treatment outcome in four consecutive BFM trials. Berlin-Frankfurt-Münster Group.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2895034

29 October 2018

Cellular cytotoxic drug sensitivity in children with acute leukemia and Down's syndrome: an explanation to differences in clinical outcome?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20418240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patient characteristics associated with high-risk methotrexate concentrations and toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20418240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo folic acid supplementation partially corrects in vitro methotrexate toxicity in patients with Down syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/20418240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myeloblasts from Down syndrome children with acute myeloid leukemia have increased in vitro sensitivity to cytosine arabinoside and daunorubicin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20418240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ignorability and parameter estimation in longitudinal pharmacokinetic studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20418240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Statistical graphics in pharmacokinetics and pharmacodynamics: a tutorial

1 reference

https://pubmed.ncbi.nlm.nih.gov/20418240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced folate carrier expression in acute lymphoblastic leukemia: a mechanism for ploidy but not lineage differences in methotrexate accumulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20418240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute leukaemia in children with Down syndrome: a population-based Nordic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20418240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical characteristics and outcome of children with Down syndrome and acute lymphoblastic leukemia: a Children's Cancer Group study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20418240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Individualized methotrexate dosing in children with relapsed acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20418240

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3324/HAEMATOL.2009.019778

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

1 reference

Europe PubMed Central

30 July 2017

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