(Q34071693)

30 July 2017

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title

Classification of ex vivo methotrexate resistance in acute lymphoblastic and myeloid leukaemia (English)

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30 July 2017

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Rots MG

1

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30 July 2017

Pieters R

2

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30 July 2017

Kaspers GJ

3

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30 July 2017

Veerman AJ

4

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30 July 2017

Peters GJ

5

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30 July 2017

Jansen G

6

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30 July 2017

language of work or name

English

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publication date

1 September 2000

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British Journal of Haematology

30 July 2017

published in

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30 July 2017

volume

110

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30 July 2017

issue

4

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30 July 2017

page(s)

791-800

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Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates

30 July 2017

cites work

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https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Anti-folate resistance in leukemia: treatment with “high-dose” methotrexate and citrovorum factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Karnofsky memorial lecture. Ode to methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Distinguishing between folate receptor-alpha-mediated transport and reduced folate carrier-mediated transport in L1210 leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Polyglutamation of methotrexate. Is methotrexate a prodrug?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Purification and properties of human cytosolic folylpoly-gamma-glutamate synthetase and organization, localization, and differential splicing of its gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Heterogeneity in the specific activity and methotrexate sensitivity of dihydrofolate reductase from blast cells of acute myelogenous leukemia patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Methotrexate resistance in an in vivo mouse tumor due to a non-active-site dihydrofolate reductase mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Expression cloning of a human cDNA encoding folylpoly(gamma-glutamate) synthetase and determination of its primary structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

The cellular pharmacology of methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Isolation and characterization of genomic sequences involved in the regulation of the human reduced folate carrier gene (RFC1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Methotrexate cytotoxicity determination using the MTT assay following enzymatic depletion of thymidine and hypoxanthine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

A structurally altered human reduced folate carrier with increased folic acid transport mediates a novel mechanism of antifolate resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

In vitro drug sensitivity of normal peripheral blood lymphocytes and childhood leukaemic cells from bone marrow and peripheral blood

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

MRP3, an organic anion transporter able to transport anti-cancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Accumulation of methotrexate polyglutamates in lymphoblasts is a determinant of antileukemic effects in vivo. A rationale for high-dose methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Assignment of human dihydrofolate reductase gene to band q23 of chromosome 5 and of related pseudogene psi HD1 to chromosome 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Methotrexate transport and resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Everything you always wanted to know about cellular drug resistance in childhood acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Molecular cloning of the human placental folate transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Folate receptor type beta is a neutrophilic lineage marker and is differentially expressed in myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

A single amino acid difference within the folate transporter encoded by the murine RFC-1 gene selectively alters its interaction with folate analogues. Implications for intrinsic antifolate resistance and directional orientation of the transporter w

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Gene amplification in cultured animal cells

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Carrier-mediated membrane transport of folates in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Characterization of a mutation in the reduced folate carrier in a transport defective L1210 murine leukemia cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Marked improvements in outcome with chemotherapy alone in paediatric acute myeloid leukemia: results of the United Kingdom Medical Research Council's 10th AML trial. MRC Childhood Leukaemia Working Party.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Mutations in the reduced folate carrier gene which confer dominant resistance to 5,10-dideazatetrahydrofolate

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Isolation of a human cDNA that complements a mutant hamster cell defective in methotrexate uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Structural organization of the human reduced folate carrier gene: evidence for 5' heterogeneity in lymphoblast mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Isolation of human cDNAs that restore methotrexate sensitivity and reduced folate carrier activity in methotrexate transport-defective Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Impaired membrane transport in methotrexate-resistant CCRF-CEM cells involves early translation termination and increased turnover of a mutant reduced folate carrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Human gamma-glutamyl hydrolase: cloning and characterization of the enzyme expressed in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

Transcript heterogeneity of the human reduced folate carrier results from the use of multiple promoters and variable splicing of alternative upstream exons

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2141.2000.02070.X

10.1046/J.1365-2141.2000.02070.X

21 January 2018

Identifiers

DOI

1 reference

30 July 2017

1 reference