(Q34073898)

30 July 2017

title

Mapping topoisomerase sites in mitochondrial DNA with a poisonous mitochondrial topoisomerase I (Top1mt). (English)

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30 July 2017

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1

Ilaria Dalla Rosa

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Yves Pommier

6

object named as

Yves Pommier

1 reference

30 July 2017

Shar-Yin N Huang

2

1 reference

30 July 2017

Keli Agama

3

1 reference

30 July 2017

Salim Khiati

4

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30 July 2017

Hongliang Zhang

5

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30 July 2017

language of work or name

English

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publication date

5 May 2014

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Journal of Biological Chemistry

30 July 2017

published in

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30 July 2017

volume

289

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30 July 2017

issue

26

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30 July 2017

page(s)

18595-18602

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Increased negative supercoiling of mtDNA in TOP1mt knockout mice and presence of topoisomerases IIα and IIβ in vertebrate mitochondria

30 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Mitochondrial topoisomerase I (top1mt) is a novel limiting factor of doxorubicin cardiotoxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I.

5 July 2018

1 reference

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Minimizing the damage: repair pathways keep mitochondrial DNA intact

5 July 2018

1 reference

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A kinetic clutch governs religation by type IB topoisomerases and determines camptothecin sensitivity

5 July 2018

1 reference

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Mitophagy: mechanisms, pathophysiological roles, and analysis

5 July 2018

1 reference

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Mitochondrial topoisomerase I is critical for mitochondrial integrity and cellular energy metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

R loops: from transcription byproducts to threats to genome stability

5 July 2018

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The interface of transcription and DNA replication in the mitochondria

5 July 2018

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Interfacial inhibitors: targeting macromolecular complexes

5 July 2018

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Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Distinguishing the roles of Topoisomerases I and II in relief of transcription-induced torsional stress in yeast rRNA genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Cellular strategies for regulating DNA supercoiling: a single-molecule perspective

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

DNA topoisomerases and their poisoning by anticancer and antibacterial drugs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Quantitative evaluation of the mitochondrial DNA depletion syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Adaptation of topoisomerase I paralogs to nuclear and mitochondrial DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Mitochondrial topoisomerase I sites in the regulatory D-loop region of mitochondrial DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

DNA replication and transcription in mammalian mitochondria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Initiation and beyond: multiple functions of the human mitochondrial transcription machinery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Topoisomerase I inhibitors: camptothecins and beyond

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Synthesis and mechanism of action studies of a series of norindenoisoquinoline topoisomerase I poisons reveal an inhibitor with a flipped orientation in the ternary DNA-enzyme-inhibitor complex as determined by X-ray crystallographic analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Thirteen-exon-motif signature for vertebrate nuclear and mitochondrial type IB topoisomerases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Nonlinear partial differential equations and applications: The mechanism of topoisomerase I poisoning by a camptothecin analog

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Human mitochondrial topoisomerase I

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

DNA topoisomerases: structure, function, and mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Topoisomerase I-mediated DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Analysis of the biased distribution of topoisomerase I break sites on replicating simian virus 40 DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Hypernegative supercoiling of the DNA template during transcription elongation in vitro.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Comparison of topoisomerase I inhibition, DNA damage, and cytotoxicity of camptothecin derivatives presently in clinical trials

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Sequence and organization of the human mitochondrial genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Elongation of displacement-loop strands in human and mouse mitochondrial DNA is arrested near specific template sequences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Supercoiling of the DNA template during transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Eukaryotic topoisomerase I-DNA interaction is stabilized by helix curvature

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Displacement-loop replication initiation sequence in animal mitochondrial DNA exists as a family of discrete lengths

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4140277

Substitutions of Asn-726 in the active site of yeast DNA topoisomerase I define novel mechanisms of stabilizing the covalent enzyme-DNA intermediate.

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.555367

Substitution of conserved residues within the active site alters the cleavage religation equilibrium of DNA topoisomerase I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.555367

DNA cleavage assay for the identification of topoisomerase I inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.555367

Subcellular localization of the camptothecin analogues, topotecan and gimatecan

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.555367

Clinical and molecular features of mitochondrial DNA depletion due to mutations in deoxyguanosine kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.555367

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

21 January 2018

1 reference

12 December 2020

Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin

1 reference

12 December 2020

Lipid bilayer partitioning and stability of camptothecin drugs

1 reference

12 December 2020

Alterations in the catalytic activity of yeast DNA topoisomerase I result in cell cycle arrest and cell death

1 reference

12 December 2020

Mechanism of mitochondrial DNA replication in mouse L-cells: Kinetics of synthesis and turnover of the initiation sequence

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M114.555367

1 reference

30 July 2017

1 reference

30 July 2017

1 reference