(Q34104464)

31 July 2017

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title

L1CAM malfunction in the nervous system and human carcinomas (English)

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31 July 2017

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2

Peter Altevogt

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31 July 2017

Michael K E Schäfer

1

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31 July 2017

publication date

17 March 2010

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Cellular and Molecular Life Sciences

31 July 2017

published in

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31 July 2017

volume

67

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31 July 2017

issue

14

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31 July 2017

page(s)

2425-2437

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https://scigraph.springernature.com/pub.10.1007/s00018-010-0339-1

31 July 2017

exact match

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cites work

Cell adhesion molecule L1 in folded (horseshoe) and extended conformations

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00018-010-0339-1

Involvement of integrin alpha(v)beta(3) and cell adhesion molecule L1 in transendothelial migration of melanoma cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00018-010-0339-1

Functional expression of a full-length cDNA coding for rat neural cell adhesion molecule L1 mediates homophilic intercellular adhesion and migration of cerebellar neurons

21 January 2018

1 reference

12 December 2020

Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesion

1 reference

12 December 2020

Alcohol inhibits cell-cell adhesion mediated by human L1

1 reference

12 December 2020

ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles

1 reference

12 December 2020

Nephrogenic diabetes insipidus in a patient with L1 syndrome: a new report of a contiguous gene deletion syndrome including L1CAM and AVPR2.

1 reference

12 December 2020

L1 cell adhesion molecule (L1CAM) in invasive tumors.

1 reference

12 December 2020

Expanding the phenotypic spectrum of L1CAM-associated disease.

1 reference

12 December 2020

Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

1 reference

12 December 2020

Errors in corticospinal axon guidance in mice lacking the neural cell adhesion molecule L1.

1 reference

12 December 2020

Up-regulation of L1CAM in pancreatic duct cells is transforming growth factor beta1- and slug-dependent: role in malignant transformation of pancreatic cancer

1 reference

12 December 2020

Nuclear translocation and signalling of L1-CAM in human carcinoma cells requires ADAM10 and presenilin/gamma-secretase activity

1 reference

12 December 2020

Expression of L1-CAM and ADAM10 in human colon cancer cells induces metastasis.

1 reference

12 December 2020

Role of neuropsin in formation and maturation of Schaffer-collateral L1cam-immunoreactive synaptic boutons

1 reference

12 December 2020

Drug-induced expression of the cellular adhesion molecule L1CAM confers anti-apoptotic protection and chemoresistance in pancreatic ductal adenocarcinoma cells

1 reference

12 December 2020

Abnormalities in neuronal process extension, hippocampal development, and the ventricular system of L1 knockout mice.

1 reference

12 December 2020

L1-associated diseases: clinical geneticists divide, molecular geneticists unite.

1 reference

12 December 2020

Impaired expression of neural cell adhesion molecule L1 in the extrinsic nerve fibers in Hirschsprung's disease

1 reference

12 December 2020

Alterations in hippocampal GAP-43, BDNF, and L1 following sustained cerebral ischemia.

1 reference

12 December 2020

SCG3 transcript in peripheral blood is a prognostic biomarker for REST-deficient small cell lung cancer

1 reference

12 December 2020

NMDA-dependent proteolysis of presynaptic adhesion molecule L1 in the hippocampus by neuropsin

1 reference

12 December 2020

Genetic and clinical aspects of X-linked hydrocephalus (L1 disease): Mutations in the L1CAM gene

1 reference

12 December 2020

A developmental study of soluble L1.

1 reference

12 December 2020

Hirschsprung's disease, acrocallosal syndrome, and congenital hydrocephalus: report of 2 patients and literature review

1 reference

12 December 2020

Metalloproteinase-mediated release of the ectodomain of L1 adhesion molecule

1 reference

12 December 2020

Functional analysis of posttranslational cleavage products of the neuron-glia cell adhesion molecule, Ng-CAM.

1 reference

12 December 2020

New domains of neural cell-adhesion molecule L1 implicated in X-linked hydrocephalus and MASA syndrome

1 reference

12 December 2020

The cytoplasmic part of L1-CAM controls growth and gene expression in human tumors that is reversed by therapeutic antibodies

1 reference

12 December 2020

Anti-neuroblastoma antibody chCE7 binds to an isoform of L1-CAM present in renal carcinoma cells

1 reference

12 December 2020

Biosynthesis and membrane topography of the neural cell adhesion molecule L1.

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12 December 2020

Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes

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12 December 2020

L1 is associated with micrometastatic spread and poor outcome in colorectal cancer

1 reference

12 December 2020

Endocytosis of beta1 integrins is an early event in migration promoted by the cell adhesion molecule L1.

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12 December 2020

Enteric nervous system development and Hirschsprung's disease: advances in genetic and stem cell studies

1 reference

12 December 2020

The neural cell adhesion molecule L1 interacts with the AP-2 adaptor and is endocytosed via the clathrin-mediated pathway

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12 December 2020

Differential expression of alternatively spliced neural cell adhesion molecule L1 isoforms during oligodendrocyte maturation.

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12 December 2020

alpha5-integrin is crucial for L1CAM-mediated chemoresistance in pancreatic adenocarcinoma.

1 reference

12 December 2020

Disruption of the mouse L1 gene leads to malformations of the nervous system

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12 December 2020

Bravo/Nr-CAM is closely related to the cell adhesion molecules L1 and Ng-CAM and has a similar heterodimer structure

1 reference

12 December 2020

Serine phosphorylation by casein kinase II controls endocytic L1 trafficking and axon growth

1 reference

12 December 2020

The intracellular interactions of the L1 family of cell adhesion molecules.

1 reference

12 December 2020

Cell adhesion molecule L1 disrupts E-cadherin-containing adherens junctions and increases scattering and motility of MCF7 breast carcinoma cells

1 reference

12 December 2020

The differential role of L1 in ovarian carcinoma and normal ovarian surface epithelium

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12 December 2020

Octanol antagonism of ethanol teratogenesis.

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12 December 2020

Got RIP? Presenilin-dependent intramembrane proteolysis in growth factor receptor signaling

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12 December 2020

Ethanol inhibits L1 cell adhesion molecule activation of mitogen-activated protein kinases

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12 December 2020

A potential role for the plasmin(ogen) system in the posttranslational cleavage of the neural cell adhesion molecule L1.

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12 December 2020

L1 expression as a predictor of progression and survival in patients with uterine and ovarian carcinomas.

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12 December 2020

Cis and trans interactions of L1 with neuropilin-1 control axonal responses to semaphorin 3A.

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12 December 2020

L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1.

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12 December 2020

Neural cell recognition molecule L1: from cell biology to human hereditary brain malformations

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12 December 2020

A genetic screen for candidate tumor suppressors identifies REST

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12 December 2020

The L1 cell adhesion molecule is induced in renal cancer cells and correlates with metastasis in clear cell carcinomas

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12 December 2020

A modifier locus on chromosome 5 contributes to L1 cell adhesion molecule X-linked hydrocephalus in mice

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12 December 2020

FAK-MAPK-dependent adhesion disassembly downstream of L1 contributes to semaphorin3A-induced collapse

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12 December 2020

Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease.

1 reference

12 December 2020

Activation of the MAPK signal cascade by the neural cell adhesion molecule L1 requires L1 internalization

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12 December 2020

Pathological missense mutations of neural cell adhesion molecule L1 affect homophilic and heterophilic binding activities.

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12 December 2020

The cytoplasmic domain of the cell adhesion molecule L1 is not required for homophilic adhesion

1 reference

12 December 2020

Genome-wide association study identifies NRG1 as a susceptibility locus for Hirschsprung's disease

1 reference

12 December 2020

L1CAM mutation in a boy with hydrocephalus and duplex kidneys.

1 reference

12 December 2020

An updated and upgraded L1CAM mutation database

1 reference

12 December 2020

The L1 adhesion molecule supports alpha v beta 3-mediated migration of human tumor cells and activated T lymphocytes

1 reference

12 December 2020

A conserved role for Drosophila Neuroglian and human L1-CAM in central-synapse formation.

1 reference

12 December 2020

Ethanol does not inhibit the adhesive activity of Drosophila neuroglian or human L1 in Drosophila S2 tissue culture cells.

1 reference

12 December 2020

Cell adhesion molecule L1 affects the rate of differentiation of enteric neurons in the developing gut.

1 reference

12 December 2020

The cell adhesion molecule L1 is developmentally regulated in the renal epithelium and is involved in kidney branching morphogenesis

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12 December 2020

Kinetic analysis of L1 homophilic interaction: role of the first four immunoglobulin domains and implications on binding mechanism

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12 December 2020

L1 expression as a marker for poor prognosis, tumor progression, and short survival in patients with colorectal cancer

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12 December 2020

Neural cell recognition molecule L1: relating biological complexity to human disease mutations

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12 December 2020

The L1CAM extracellular region: a multi-domain protein with modular and cooperative binding modes

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12 December 2020

Abnormal renal phenotype in L1 knockout mice: a novel cause of CAKUT.

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12 December 2020

L1 interaction with ankyrin regulates mediolateral topography in the retinocollicular projection.

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12 December 2020

Brain development in mice lacking L1-L1 homophilic adhesion

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12 December 2020

Nuclear signalling by tumour-associated antigen EpCAM

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12 December 2020

Ankyrin binding mediates L1CAM interactions with static components of the cytoskeleton and inhibits retrograde movement of L1CAM on the cell surface

1 reference

12 December 2020

Release of the NILE and other glycoproteins from cultured PC12 rat pheochromocytoma cells and sympathetic neurons

1 reference

12 December 2020

Clinical aspects of the MASA syndrome in a large family, including expressing females.

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12 December 2020

Structural basis of Dscam isoform specificity

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12 December 2020

Neural recognition molecules of the immunoglobulin superfamily: signaling transducers of axon guidance and neuronal migration

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12 December 2020

Differential effects of ethanol antagonism and neuroprotection in peptide fragment NAPVSIPQ prevention of ethanol-induced developmental toxicity

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12 December 2020

Gene expression of neural cell adhesion molecule L1 in malignant gliomas and biological significance of L1 in glioma invasion.

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12 December 2020

Alternative use of a mini exon of the L1 gene affects L1 binding to neural ligands

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12 December 2020

Disease-associated mutations in L1 CAM interfere with ligand interactions and cell-surface expression

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12 December 2020

The soluble form of the cancer-associated L1 cell adhesion molecule is a pro-angiogenic factor.

1 reference

12 December 2020

Neuropilin is a receptor for the axonal chemorepellent Semaphorin III

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12 December 2020

L1 on ovarian carcinoma cells is a binding partner for Neuropilin-1 on mesothelial cells

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12 December 2020

Abnormal corticospinal function but normal axonal guidance in human L1CAM mutations

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12 December 2020

L1, a novel target of beta-catenin signaling, transforms cells and is expressed at the invasive front of colon cancers

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12 December 2020

Elevated levels of neural recognition molecule L1 in the cerebrospinal fluid of patients with Alzheimer disease and other dementia syndromes.

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12 December 2020

Ethanol inhibits L1 cell adhesion molecule tyrosine phosphorylation and dephosphorylation and activation of pp60(src).

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12 December 2020

L1 augments cell migration and tumor growth but not beta3 integrin expression in ovarian carcinomas

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12 December 2020

Neuropilin is a semaphorin III receptor

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12 December 2020

The cell adhesion molecule l1 is required for chain migration of neural crest cells in the developing mouse gut.

1 reference

12 December 2020

DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome

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12 December 2020

Neurite outgrowth promoting activity of G4 and its inhibition by monoclonal antibodies

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12 December 2020

Function and regulation of Dyrk1A: towards understanding Down syndrome

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12 December 2020

Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin alpha v beta 3

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12 December 2020

Polycomblike-2-deficient mice exhibit normal left-right asymmetry

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12 December 2020

Molecular analysis of the L1CAM gene in patients with X-linked hydrocephalus demonstrates eight novel mutations and suggests non-allelic heterogeneity of the trait

1 reference

12 December 2020

A nonneuronal isoform of cell adhesion molecule L1: tissue-specific expression and functional analysis

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12 December 2020

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

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12 December 2020

Mapping of a Hirschsprung's disease locus in 3p21

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12 December 2020

Neuronal expression of zinc finger transcription factor REST/NRSF/XBR gene

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12 December 2020

Neurite growth on different substrates: permissive versus instructive influences and the role of adhesive strength

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12 December 2020

Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance

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12 December 2020

The crystal structure of the ligand binding module of axonin-1/TAG-1 suggests a zipper mechanism for neural cell adhesion

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12 December 2020

Molecular mechanisms and neuroimaging criteria for severe L1 syndrome with X-linked hydrocephalus.

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12 December 2020

Presenilin: running with scissors in the membrane

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12 December 2020

Ethanol inhibits neural cell-cell adhesion

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12 December 2020

Cytoplasmic domain mutations of the L1 cell adhesion molecule reduce L1-ankyrin interactions.

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12 December 2020

DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome.

1 reference

12 December 2020

Complex pathogenesis of Hirschsprung's disease in a patient with hydrocephalus, vesico-ureteral reflux and a balanced translocation t(3;17)(p12;q11).

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12 December 2020

DNA hypomethylation at the CpG island is involved in aberrant expression of the L1 cell adhesion molecule gene in colorectal cancer.

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12 December 2020

Hydrocephalus and intestinal aganglionosis: is L1CAM a modifier gene in Hirschsprung disease?

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12 December 2020

Alphav beta3 integrin limits the contribution of neuropilin-1 to vascular endothelial growth factor-induced angiogenesis

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12 December 2020

Hydrocephalus and Hirschsprung's disease in a patient with a mutation of L1CAM.

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12 December 2020

RE-1-silencing transcription factor shows tumor-suppressor functions and negatively regulates the oncogenic TAC1 in breast cancer cells

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12 December 2020

L1 and NCAM adhesion molecules as signaling coreceptors in neuronal migration and process outgrowth

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12 December 2020

The neural cell adhesion molecule L1 potentiates integrin-dependent cell migration to extracellular matrix proteins.

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12 December 2020

Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins

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12 December 2020

Biochemical characterization of different molecular forms of the neural cell adhesion molecule L1.

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12 December 2020

Extracellular signal-regulated kinase (ERK)-dependent gene expression contributes to L1 cell adhesion molecule-dependent motility and invasion

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12 December 2020

CRASH syndrome: mutations in L1CAM correlate with severity of the disease

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12 December 2020

The proprotein convertase PC5A and a metalloprotease are involved in the proteolytic processing of the neural adhesion molecule L1.

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12 December 2020

Copper-67 radioimmunotherapy and growth inhibition by anti-L1-cell adhesion molecule monoclonal antibodies in a therapy model of ovarian cancer metastasis

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12 December 2020

The RGD integrin binding site in human L1-CAM is important for nuclear signaling

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12 December 2020

Matrix-bound sixth Ig-like domain of cell adhesion molecule L1 acts as an angiogenic factor by ligating alphavbeta3-integrin and activating VEGF-R2.

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12 December 2020

Role of Src kinases in the ADAM-mediated release of L1 adhesion molecule from human tumor cells

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12 December 2020

Biochemical characterization of polypeptide components involved in neurite fasciculation and elongation.

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12 December 2020

Hirschsprung disease, associated syndromes and genetics: a review

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12 December 2020

An alcohol binding site on the neural cell adhesion molecule L1

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12 December 2020

Ethanol inhibits L1-mediated neurite outgrowth in postnatal rat cerebellar granule cells

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12 December 2020

L1 mediated homophilic binding and neurite outgrowth are modulated by alternative splicing of exon 2.

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12 December 2020

Tissue-specific expression of the L1 cell adhesion molecule is modulated by the neural restrictive silencer element

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12 December 2020

L1 adhesion molecule on mouse leukocytes: regulation and involvement in endothelial cell binding

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12 December 2020

Enhanced L1CAM expression on pancreatic tumor endothelium mediates selective tumor cell transmigration

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12 December 2020

Ischemic insults derepress the gene silencer REST in neurons destined to die

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12 December 2020

Effects of ethanol on axon outgrowth and branching in developing rat cortical neurons

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12 December 2020

Efficient inhibition of intra-peritoneal tumor growth and dissemination of human ovarian carcinoma cells in nude mice by anti-L1-cell adhesion molecule monoclonal antibody treatment

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12 December 2020

Pathogenic human L1-CAM mutations reduce the adhesion-dependent activation of EGFR.

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12 December 2020

L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth

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12 December 2020

10.1007/S00018-010-0339-1

Identifiers

DOI

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31 July 2017

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