(Q34125558)

31 July 2017

title

Estrogen receptor beta decreases survival of p53-defective cancer cells after DNA damage by impairing G₂/M checkpoint signaling (English)

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31 July 2017

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Christoforos G Thomas

1

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31 July 2017

Anders Strom

2

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31 July 2017

Karolina Lindberg

3

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31 July 2017

Jan-Ake Gustafsson

4

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31 July 2017

language of work or name

English

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publication date

10 July 2010

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Breast Cancer Research and Treatment

31 July 2017

published in

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31 July 2017

volume

127

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31 July 2017

issue

2

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31 July 2017

page(s)

417-427

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Checkpoints: controls that ensure the order of cell cycle events

31 July 2017

cites work

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p53 mediates repression of the BRCA2 promoter and down-regulation of BRCA2 mRNA and protein levels in response to DNA damage

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Tumor suppressor p53 is required to modulate BRCA1 expression

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Recent advances in cancer therapy targeting proteins involved in DNA double-strand break repair.

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p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage

21 January 2018

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10.1007/S10549-010-1011-Z

21 January 2018

Identifiers

DOI

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Dimensions Publication ID

31 July 2017

1018679130

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